Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Fernando Segade"'
Publikováno v:
EvoDevo, Vol 7, Iss 1, Pp 1-16 (2016)
Abstract Background Genomic analysis has upended chordate phylogeny, placing the tunicates as the sister group to the vertebrates. This taxonomic rearrangement raises questions about the emergence of a tunicate/vertebrate ancestor. Results Characteri
Externí odkaz:
https://doaj.org/article/1384d0eb41454eea8214cb7fab543229
Autor:
Michèle M Sale, Wei-Min Chen, Daniel E Weeks, Josyf C Mychaleckyj, Xuanlin Hou, Miranda Marion, Fernando Segade, Margaretha L Casselbrant, Ellen M Mandel, Robert E Ferrell, Stephen S Rich, Kathleen A Daly
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22297 (2011)
DNA sequence variants in genes involved in the innate immune response and secondary response to infection may confer susceptibility to chronic otitis media with effusion and/or recurrent otitis media (COME/ROM). We evaluated single nucleotide polymor
Externí odkaz:
https://doaj.org/article/b9834362dc704b539b292203a408e67d
Autor:
Stephen S. Rich, Ellen M. Mandel, Fang Chen, Robert E. Ferrell, Jose L. Mattos, Margaretha L. Casselbrant, E. Kaitlynn Allen, Daniel E. Weeks, Josyf C. Mychaleckyj, Kathleen Daly, Michèle M. Sale, Xuanlin Hou, Fernando Segade, Wei-Min Chen
Publikováno v:
Journal of the Association for Research in Otolaryngology. 14:791-800
Chronic otitis media with effusion (COME) and recurrent otitis media (ROM) have been shown to be heritable, but candidate gene and linkage studies to date have been equivocal. Our aim was to identify genetic susceptibility factors using a genome-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3df00301c3a5c0330d73b39b2c99e45
https://doi.org/10.1007/s10162-013-0411-2
https://doi.org/10.1007/s10162-013-0411-2
Publikováno v:
EvoDevo
EvoDevo, Vol 7, Iss 1, Pp 1-16 (2016)
EvoDevo, Vol 7, Iss 1, Pp 1-16 (2016)
Background Genomic analysis has upended chordate phylogeny, placing the tunicates as the sister group to the vertebrates. This taxonomic rearrangement raises questions about the emergence of a tunicate/vertebrate ancestor. Results Characterization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05f0b05c65f06ce4a0b5db75418c545
https://doi.org/10.1186/s13227-016-0056-4
https://doi.org/10.1186/s13227-016-0056-4
Autor:
Fernando Segade
Publikováno v:
Gene. 439:43-54
The microfibril-associated glycoproteins (MAGPs) are cysteine-rich low molecular weight components of the fibrillin-based microfibrillar complex. MAGPs are evolutionarily conserved in vertebrates and have important roles in microfibril and elastic fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987ea9a2fd8346a7f71bbed75dfcdc05
https://doi.org/10.1016/j.gene.2009.03.013
https://doi.org/10.1016/j.gene.2009.03.013
Autor:
Clarissa S. Craft, Robert P. Mecham, Richard A. Pierce, Fernando Segade, Claudio C. Werneck, Thomas J. Broekelmann, Justin S. Weinbaum, Russell H. Knutsen
Publikováno v:
Journal of Biological Chemistry. 283:25533-25543
Microfibril-associated glycoprotein-1 (MAGP-1) is a small molecular weight component of the fibrillin-rich microfibril. Gene-targeted inactivation of MAGP-1 reveals a complex phenotype that includes increased body weight and size due to excess body f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b38e060f54e6135621cf6e8bfec501
https://doi.org/10.1074/jbc.m709962200
https://doi.org/10.1074/jbc.m709962200
Publikováno v:
BJU International. 99:1143-1149
OBJECTIVE To investigate the differences in the pattern of glucose transporter (GLUT) gene expression between normal and tumour tissues and among histological subtypes of renal cell carcinomas (RCCs), as malignant cells are characterized by increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcebe77e6e4a39a1f7352bd36c00767
https://doi.org/10.1111/j.1464-410x.2007.06765.x
https://doi.org/10.1111/j.1464-410x.2007.06765.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1730:147-158
The human SLC2A10 gene encodes the high-affinity glucose transporter 10 (GLUT10) and is widely expressed in adult tissues, including organs which play major roles in glucose homeostasis. Its function and genomic location in a region linked to Type 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a6e4203ee5f27c5816f89e3908a5fc
https://doi.org/10.1016/j.bbaexp.2005.06.012
https://doi.org/10.1016/j.bbaexp.2005.06.012
Autor:
Robert P. Mecham, Richard A. Pierce, Thomas J. Broekelmann, Barbara Crippes Trask, Fernando Segade
Publikováno v:
Journal of Biological Chemistry. 277:11050-11057
MAGP1 is a small molecular mass protein associated with microfibrils in the extracellular matrix (ECM). To identify the molecular basis of its interaction with other microfibrillar proteins, deletion constructs of MAGP1 were expressed in a mammalian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a7191ad379f11c6bfdec8514ab0d2d
https://doi.org/10.1074/jbc.m110347200
https://doi.org/10.1074/jbc.m110347200
Publikováno v:
Matrix Biology. 19:671-682
The human MAGP1 (or MFAP2) and mouse Magp1 genes code for the microfibril-associated glycoprotein-1 (MAGP-1), an extracellular matrix protein of microfibrillar structures. We report a revised 5' genomic structure including the use of a single transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a34f05c8e0a882dba0a7e60eef7dbb8
https://doi.org/10.1016/s0945-053x(00)00115-3
https://doi.org/10.1016/s0945-053x(00)00115-3