Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Fernando Sanz-García"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17355 (2023)
The identification of targets whose inactivation increases the activity of antibiotics helps to fight antibiotic resistance. Previous work showed that a transposon-insertion mutant in the gene PA14_27940 increases Pseudomonas aeruginosa susceptibilit
Externí odkaz:
https://doaj.org/article/bae8bfaab05246bf871f0fe94d3cf6c3
Autor:
Sara Hernando-Amado, Carla López-Causapé, Pablo Laborda, Fernando Sanz-García, Antonio Oliver, José Luis Martínez
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Collateral sensitivity (CS) is an evolutionary trade-off by which acquisition of resistance to an antibiotic leads to increased susceptibility to another. This Achilles’ heel of antibiotic resistance could be exploited to design evolution-
Externí odkaz:
https://doaj.org/article/ec2b2bc4c4c04ff49b473849d3a5dfda
Autor:
Fernando Sanz-García, Sara Hernando-Amado, Carla López-Causapé, Antonio Oliver, José Luis Martínez
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Low antibiotic concentrations present in natural environments are a severe and often neglected threat to public health. Even if they are present below their MICs, they may select for antibiotic-resistant pathogens. Notably, the minimal subin
Externí odkaz:
https://doaj.org/article/7af90d757ae54b478a91ef887aa92ef5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 6892 (2023)
Understanding the consequences in bacterial physiology of the acquisition of drug resistance is needed to identify and exploit the weaknesses derived from it. One of them is collateral sensitivity, a potentially exploitable phenotype that, unfortunat
Externí odkaz:
https://doaj.org/article/e18db0a25c994cd6aab6daa7f680da80
Autor:
Pablo Laborda, Fernando Sanz-García, Luz Edith Ochoa-Sánchez, Teresa Gil-Gil, Sara Hernando-Amado, José Luis Martínez
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Antibiotic resistance is a major human health problem. While health care facilities are main contributors to the emergence, evolution and spread of antibiotic resistance, other ecosystems are involved in such dissemination. Wastewater, farm animals a
Externí odkaz:
https://doaj.org/article/e3c757d49f8146c6920cc3c590dc9da0
Autor:
Fernando Sanz-García, Teresa Gil-Gil, Pablo Laborda, Luz E. Ochoa-Sánchez, José L. Martínez, Sara Hernando-Amado
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8080 (2021)
The use and misuse of antibiotics have made antibiotic-resistant bacteria widespread nowadays, constituting one of the most relevant challenges for human health at present. Among these bacteria, opportunistic pathogens with an environmental, non-clin
Externí odkaz:
https://doaj.org/article/46547acabf5642669b246073f7571179
Autor:
Teresa Gil‐Gil, Pablo Laborda, Fernando Sanz‐García, Sara Hernando‐Amado, Paula Blanco, José Luis Martínez
Publikováno v:
MicrobiologyOpen, Vol 8, Iss 11, Pp n/a-n/a (2019)
Abstract Infectious diseases still stand as a major cause of morbidity and mortality, and this problem can be worsened with the current antimicrobial resistance crisis. To tackle this crisis more studies analyzing the causes, routes, and reservoirs w
Externí odkaz:
https://doaj.org/article/77ae1e80956e48bc8002ee648d9d56e0
Autor:
Fernando Sanz-García, Ernesto Anoz-Carbonell, Esther Pérez-Herrán, Carlos Martín, Ainhoa Lucía, Liliana Rodrigues, José A. Aínsa
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Aminoglycoside acetyltransferases are important determinants of resistance to aminoglycoside antibiotics in most bacterial genera. In mycobacteria, however, aminoglycoside acetyltransferases contribute only partially to aminoglycoside susceptibility
Externí odkaz:
https://doaj.org/article/84950555c822450289135d3f1a2a2ed5
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
The present work examines the evolutionary trajectories of replicate Pseudomonas aeruginosa cultures in presence of the ribosome-targeting antibiotics tobramycin and tigecycline. It is known that large number of mutations across different genes – a
Externí odkaz:
https://doaj.org/article/0065bf4cf96241329960da98c0399ffc
Autor:
Fernando Sanz-García, Teresa Gil-Gil, Pablo Laborda, Paula Blanco, Luz-Edith Ochoa-Sánchez, Fernando Baquero, José Luis Martínez, Sara Hernando-Amado
Publikováno v:
Nature Reviews Microbiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b53a5447601d0adeac864408d1ec1af3
https://doi.org/10.1038/s41579-023-00902-5
https://doi.org/10.1038/s41579-023-00902-5