Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fernando Sánchez-Cantalejo"'
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Gold‐catalysed oxidative cyclisation reactions of ynamides offer great promise in γ‐lactam synthesis but are limited by preferential over‐oxidation to form α‐keto imides. Evaluating the factors that might limit N‐cyclisation pathways led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ccf830a7eb55ca0fc2c4d3fe3ae86fc
https://pubmed.ncbi.nlm.nih.gov/30248205
https://pubmed.ncbi.nlm.nih.gov/30248205
Publikováno v:
European Journal of Organic Chemistry. 2011:7182-7188
The synthesis of two pentahydroxylated pyrrolizidines, hyacinthacine C5 (1) and 6,7-di-epi-hyacinthacine C5 (12), from an orthogonally protected pyrrolidine of 2,5-dideoxy-2,5-imino-D-mannitol configuration (i.e., 7) is described. The analytical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6ead5ee4920573127473fc2013ac7d
https://doi.org/10.1002/ejoc.201101126
https://doi.org/10.1002/ejoc.201101126
Publikováno v:
Tetrahedron. 66:7262-7267
Stereocontrolled synthesis of 5- epi - and 5,7a-di- epi -hyacinthacine C 1 ( 7 and 8 ), two potential glycosidase inhibitors are described using α,β-unsaturated ketone 9 as homochiral starting material. The key step in the synthesis is the highly d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1217e84dfed9f48cd4e17b9b097c1861
https://doi.org/10.1016/j.tet.2010.07.019
https://doi.org/10.1016/j.tet.2010.07.019
Autor:
Fernando Sánchez-Cantalejo, Isidoro Izquierdo, Francisco Franco, María T. Plaza, Juan A. Tamayo
Publikováno v:
Tetrahedron. 66:3788-3794
Naturally occurring (1 S ,2 R ,3 R ,5 R ,7a R )-1,2-dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine [(+)-hyacinthacine A 6 , 2 ] together with unnatural (1 S ,2 R ,3 R ,7a S )-1,2-dihydroxy-3-hydroxymethylpyrrolizidine [(+)-7a- epi -hyacinthacine A 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2680651028e7630497f93b2b996c458
https://doi.org/10.1016/j.tet.2010.03.049
https://doi.org/10.1016/j.tet.2010.03.049
Publikováno v:
The Journal of Organic Chemistry. 74:5679-5682
1,3-Dipolar cycloaddition reaction of nitrone 7 and chemo-enzymatically obtained alkenediols 12 and 13 has been used in the synthesis of pentahydroxylated pyrrolizidines (8 and 10) and indolizidines (9 and 11). The pyrrolizidinic and indolizidinic sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c2eb9bf58ae85ec5c195088f676c82
https://doi.org/10.1021/jo900801c
https://doi.org/10.1021/jo900801c
Publikováno v:
Synthesis. 2008:1373-1378
A series of naturally occurring pyrrolidine alkaloids and analogues, with the general structure of trideoxy-2,5-iminohexitols (imino- or azasugars), have been enantiosynthesized using triorthogonally protected pyrrolidines, previously prepared from c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda156da6ba77c0eb41e8df771689620
https://doi.org/10.1055/s-2008-1072566
https://doi.org/10.1055/s-2008-1072566
Autor:
Isidoro Izquierdo, Fernando Sánchez-Cantalejo, Juan A. Tamayo, María T. Plaza, Francisco Franco
Publikováno v:
Tetrahedron. 64:4993-4998
Syntheses of 2,5,6-trideoxy-2,5-imino- d -alditol ( 2 , 6-deoxy-DADP) and its enantiomer ( 3 ) from tri-orthogonally protected derivatives of DADP have been developed employing lipase-mediated kinetic desymmetrization and protecting group manipulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ca4e0d0ed83d73516396334505c8bc
https://doi.org/10.1016/j.tet.2008.03.089
https://doi.org/10.1016/j.tet.2008.03.089
Autor:
Fernando Sánchez-Cantalejo, María T. Plaza, Juan A. Tamayo, Isidoro Izquierdo, Víctor Yáñez, Daniele Lo Re
Publikováno v:
Tetrahedron. 64:4613-4618
A convergent synthesis of the naturally occurring alkaloid (−)-hyacinthacine A 7 , a glycosidase inhibitor of the pyrrolizidine class, is described. The homochiral starting material was tri-orthogonally protected DMDP 10 , derived from d -fructose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7a796aeed1a138cf5f92cda004b1378
https://doi.org/10.1016/j.tet.2008.03.009
https://doi.org/10.1016/j.tet.2008.03.009
Publikováno v:
Tetrahedron: Asymmetry. 18:2211-2217
(1 R ,2 S ,3 R ,5 S ,7a R )-1,2-Dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine 10 [(+)-5- epi hyacinthacine A 5 ] and (1 R ,2 S ,3 R ,5 S ,7a S )-1,2-dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine 17 [ ent -5- epi hyacinthacine A 4 ] have been synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d911e340c4163482f239a8fb1804fb2
https://doi.org/10.1016/j.tetasy.2007.09.014
https://doi.org/10.1016/j.tetasy.2007.09.014
Publikováno v:
Tetrahedron Letters. 50:3145-3147
The thermolysis of several imidofuranyl carbamates delivers products derived from an intramolecular [4+2]-cycloaddition reaction. In the case of the ortho-azido aryl carbamate 13, the preferred path proceeds by an electrocyclization of a nitrene inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::818ed911c3b52ca114f7278472f9c526
https://doi.org/10.1016/j.tetlet.2008.12.088
https://doi.org/10.1016/j.tetlet.2008.12.088