Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fernando P. Varotti"'
Autor:
Fernanda A. Oliveira, Ana Claudia S. Pinto, Caique L. Duarte, Alex G. Taranto, Eder Lorenzato Junior, Cleydson Finotti Cordeiro, Diogo T. Carvalho, Fernando P. Varotti, Amanda L. Fonseca
Publikováno v:
BMC Chemistry, Vol 16, Iss 1, Pp 1-13 (2022)
Abstract N-acylhydrazones are considered privileged structures in medicinal chemistry, being part of antimicrobial compounds (for example). In this study we show the activity of N-acylhydrazone compounds, namely AH1, AH2, AH4, AH5 in in vitro tests a
Externí odkaz:
https://doaj.org/article/f3b3899391b14600960590dfc72d872a
Autor:
José A. F. P. Villar, Gustavo H. R. Viana, Leandro A. Barbosa, Fernando P. Varotti, Sarah C. Simões, Andersson Barison, Estrela M. P. V. E. Souza, Marina G. da Silva, Graziele D. da Silva
Publikováno v:
Molecules, Vol 17, Iss 9, Pp 10331-10343 (2012)
A series of new chalcones substituted with azide/triazole groups were designed and synthesized, and their cytotoxic activity was evaluated in vitro against the HeLa cell line. O-Alkylation, Claisen-Schmidt condensation and Cu(I)-catalyzed cycloadditi
Externí odkaz:
https://doaj.org/article/712b200d3ff84d7a9597cda58f3e5de1
Autor:
Alaíde B. Oliveira, Maria Fâni Dolabela, Fernão C. Braga, Rose L.R.P. Jácome, Fernando P. Varotti, Marinete M. Póvoa
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 81, Iss 4, Pp 715-740 (2009)
Malaria remains one of the most serious world health problem and the major cause of mortality and morbidity in the endemic regions. Brazil is among the 30 high-burden countries and most of the cases occur in the Legal Amazonian Region. New chemothera
Externí odkaz:
https://doaj.org/article/d9e0fe555b714c4c95965a9ef70c75fe
Autor:
Isabella Ferreira Silva, Letícia Fagundes Papa, Pedro Gontijo Carneiro, Mariane Cristina Schnitzler, Silmara Nunes Andrade, Rosy Iara Maciel Azambuja Ribeiro, Fernando Pilla Varotti, Ralph Gruppi Thomé, Hélio Batista Santos
Publikováno v:
Acta Scientiarum: Biological Sciences, Vol 43, Iss 1 (2021)
Multiwalled carbon nanotube (MWCNT) has been broadly used in several sectors of society. This material when exposed to the environment might reach the aquatic animals and cause toxic effects. Here, it was evaluated the MWCNTs toxicity in melanomacrop
Externí odkaz:
https://doaj.org/article/dd2a5ba7e2cf4c99a03c96f28aeff8b7
Autor:
Sayonarah C Rocha, Marco T C Pessoa, Luiza D R Neves, Silmara L G Alves, Luciana M Silva, Herica L Santos, Soraya M F Oliveira, Alex G Taranto, Moacyr Comar, Isabella V Gomes, Fabio V Santos, Natasha Paixão, Luis E M Quintas, François Noël, Antonio F Pereira, Ana C S C Tessis, Natalia L S Gomes, Otacilio C Moreira, Ruth Rincon-Heredia, Fernando P Varotti, Gustavo Blanco, Jose A F P Villar, Rubén G Contreras, Leandro A Barbosa
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108776 (2014)
Cardiotonic steroids are used to treat heart failure and arrhythmia and have promising anticancer effects. The prototypic cardiotonic steroid ouabain may also be a hormone that modulates epithelial cell adhesion. Cardiotonic steroids consist of a ste
Externí odkaz:
https://doaj.org/article/be6b9f94d29e4b688e9429a2fc67ac6a