Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Fernando O. Martinez"'
Autor:
Federica Orsenigo, Alexander Stewart, Clare P. Hammer, Emma Clarke, Daniel Simpkin, Hossameldin Attia, Timothy Rockall, Siamon Gordon, Fernando O. Martinez
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114352- (2024)
Summary: Addressing the mononuclear phagocyte system (MPS) and macrophage M1/M2 activation is important in diagnosing hematological disorders and inflammatory pathologies and designing therapeutic tools. CSF1R is a reliable marker to identify all cir
Externí odkaz:
https://doaj.org/article/c0e9483bd0c045cb90c8fa0245a1e38f
Autor:
Beatriz Burger, Roberta Nicolli Sagiorato, Jéssica Rondoni Silva, Thamiris Candreva, Mariana R. Pacheco, Daniel White, Bianca G. Castelucci, Laís P. Pral, Helena L. Fisk, Izadora L. A. Rabelo, Jefferson Elias-Oliveira, Wislei Riuper Osório, Silvio Roberto Consonni, Alessandro dos Santos Farias, Marco Aurélio Ramirez Vinolo, Claudiana Lameu, Daniela Carlos, Barbara A. Fielding, Martin Brunel Whyte, Fernando O. Martinez, Philip C. Calder, Hosana Gomes Rodrigues
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Delayed wound healing is a devastating complication of diabetes and supplementation with fish oil, a source of anti-inflammatory omega-3 (ω-3) fatty acids including eicosapentaenoic acid (EPA), seems an appealing treatment strategy. However, some st
Externí odkaz:
https://doaj.org/article/79239e2c0d6540828c0b6a3e610e21bd
Autor:
Antoni Olona, Subhankar Mukhopadhyay, Charlotte Hateley, Fernando O. Martinez, Siamon Gordon, Jacques Behmoaras
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Cell membrane fusion and multinucleation in macrophages are associated with physiologic homeostasis as well as disease. Osteoclasts are multinucleated macrophages that resorb bone through increased metabolic activity resulting from cell fusi
Externí odkaz:
https://doaj.org/article/2fd5b548491e4a29a5558064d1059ef3
Autor:
Manman Guo, Cemsel Bafligil, Thomas Tapmeier, Carol Hubbard, Sanjiv Manek, Catherine Shang, Fernando O. Martinez, Nicole Schmidt, Maik Obendorf, Holger Hess-Stumpp, Thomas M. Zollner, Stephen Kennedy, Christian M. Becker, Krina T. Zondervan, Adam P. Cribbs, Udo Oppermann
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Endometriosis is a gynaecological condition characterised by immune cell infiltration and distinct inflammatory signatures found in the peritoneal cavity. In this study, we aim to characterise the immune microenvironment in sample
Externí odkaz:
https://doaj.org/article/15f988e46be6442287146db61267c609
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mycobacterium tuberculosis infects primarily macrophages in the lungs. Infected macrophages are surrounded by other immune cells in well organised structures called granulomata. As part of the response to TB, a type of macrophage loaded with lipid dr
Externí odkaz:
https://doaj.org/article/e3055dfc8401479abfc4d9c14e76ef53
Autor:
Pooja Agarwal, Theo W. Combes, Fariba Shojaee-Moradie, Barbara Fielding, Siamon Gordon, Valerie Mizrahi, Fernando O. Martinez
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/97cad39e7dae470b8a8b24f38b9d553c
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102964- (2020)
ABSTRACT: Mononuclear phagocytes are a widely distributed family of cells contributing to innate and adaptive immunity. Circulating monocytes and tissue macrophages participate in all stages of SARS COVID-19. They contribute to comorbidities predispo
Externí odkaz:
https://doaj.org/article/ba3690d48f814a53a2cd7b5d639c8b00
Autor:
Pooja Agarwal, Theo W. Combes, Fariba Shojaee-Moradie, Barbara Fielding, Siamon Gordon, Valerie Mizrahi, Fernando O. Martinez
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Mycobacterium tuberculosis (Mtb) infects macrophages and macrophage-derived foam cells, a hallmark of granulomata in tuberculous lesions. We analyzed the effects of lipid accumulation in human primary macrophages and quantified strong triglyceride an
Externí odkaz:
https://doaj.org/article/ced6114d1fd24689862eb13322bf89f0
Autor:
Maria Bravo, Theo Combes, Fernando O Martinez, Rosario Cerrato, Joaquín Rey, Waldo Garcia-Jimenez, Pedro Fernandez-Llario, David Risco, Jorge Gutierrez-Merino
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Background: Wildlife poses a significant burden for the complete eradication of bovine tuberculosis (bTB). In particular, wild boar (Sus scrofa) is one of the most important reservoirs of Mycobacterium bovis, the causal agent of bTB. Wild boar can di
Externí odkaz:
https://doaj.org/article/feb801e8a22c4287bc78939315e89c9a
Autor:
Ronny Milde, Julia Ritter, Glenys A. Tennent, Andrzej Loesch, Fernando O. Martinez, Siamon Gordon, Mark B. Pepys, Admar Verschoor, Laura Helming
Publikováno v:
Cell Reports, Vol 13, Iss 9, Pp 1937-1948 (2015)
Multinucleated giant cells (MGCs) form by fusion of macrophages and are presumed to contribute to the removal of debris from tissues. In a systematic in vitro analysis, we show that IL-4-induced MGCs phagocytosed large and complement-opsonized materi
Externí odkaz:
https://doaj.org/article/83113f800f1b4f9b954b593c1e057032