Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fernando O, Carreño"'
Autor:
Jacqueline G. Gerhart, Fernando O. Carreño, Jennifer L. Ford, Andrea N. Edginton, Eliana M. Perrin, Kevin M. Watt, William J. Muller, Andrew M. Atz, Amira Al‐Uzri, Paula Delmore, Daniel Gonzalez, Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 6, Pp 778-791 (2022)
Abstract Obesity is an increasingly alarming public health threat, with nearly 20% of children classified as obese in the United States today. Children with obesity are commonly prescribed the opioids fentanyl and methadone, and accurate dosing is cr
Externí odkaz:
https://doaj.org/article/dd4ab2e51fa44b86a239b72f4ea91718
Autor:
Jacqueline G, Gerhart, Fernando O, Carreño, Matthew Shane, Loop, Craig R, Lee, Andrea N, Edginton, Jaydeep, Sinha, Karan R, Kumar, Carl M, Kirkpatrick, Christoph P, Hornik, Daniel, Gonzalez, Don, Stone
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:391-403
Dosing guidance for children with obesity is often unknown despite the fact that nearly 20% of US children are classified as obese. Enoxaparin, a commonly prescribed low-molecular-weight heparin, is dosed based on body weight irrespective of obesity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d7c22c6fcc68a82b4651b610843390
https://doi.org/10.1002/cpt.2618
https://doi.org/10.1002/cpt.2618
Autor:
Daniel Gonzalez, Michael Cohen-Wolkowiez, Karan R. Kumar, Fernando O. Carreño, Andrea N. Edginton, Vincent Harris, Jaydeep Sinha, Christoph P. Hornik, Aruna Rikhi, Eliana M. Perrin, Samit Ganguly, Jacqueline G Gerhart
Publikováno v:
Clinical Pharmacokinetics. 61:307-320
While one in five children in the USA are now obese, and more than three-quarters receive at least one drug during childhood, there is limited dosing guidance for this vulnerable patient population. Physiologically based pharmacokinetic modeling can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e2e7ccb3bcc9934e863ff2d0a1a42c
https://doi.org/10.1007/s40262-021-01072-4
https://doi.org/10.1007/s40262-021-01072-4
Autor:
Andrea N. Edginton, Sara Salerno, Michael Cohen-Wolkowiez, Fernando O. Carreño, Daniel Gonzalez
Publikováno v:
Drug Metabolism and Disposition. 49:844-855
Solithromycin is a novel fluoroketolide antibiotic that is both a substrate and time-dependent inhibitor of CYP3A. Solithromycin has demonstrated efficacy in adults with community-acquired bacterial pneumonia and has also been investigated in pediatr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47285f7407084a9398e66c3a0f389710
https://doi.org/10.1124/dmd.120.000318
https://doi.org/10.1124/dmd.120.000318