Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Fernando Martín-Belmonte"'
Autor:
Marta Iborra-Pernichi, Jonathan Ruiz García, María Velasco de la Esperanza, Belén S. Estrada, Elena R. Bovolenta, Claudia Cifuentes, Cristina Prieto Carro, Tamara González Martínez, José García-Consuegra, María Fernanda Rey-Stolle, Francisco Javier Rupérez, Milagros Guerra Rodriguez, Rafael J. Argüello, Sara Cogliati, Fernando Martín-Belmonte, Nuria Martínez-Martín
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The B cell response in the germinal centre (GC) reaction requires a unique bioenergetic supply. Although mitochondria are remodelled upon antigen-mediated B cell receptor stimulation, mitochondrial function in B cells is still poorly underst
Externí odkaz:
https://doaj.org/article/d47fc4e2cc244f8d8109bd4b0197ce3c
Autor:
Jesús A. Andrés-San Román, Carmen Gordillo-Vázquez, Daniel Franco-Barranco, Laura Morato, Cecilia H. Fernández-Espartero, Gabriel Baonza, Antonio Tagua, Pablo Vicente-Munuera, Ana M. Palacios, María P. Gavilán, Fernando Martín-Belmonte, Valentina Annese, Pedro Gómez-Gálvez, Ignacio Arganda-Carreras, Luis M. Escudero
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 10, Pp 100597- (2023)
Summary: Decades of research have not yet fully explained the mechanisms of epithelial self-organization and 3D packing. Single-cell analysis of large 3D epithelial libraries is crucial for understanding the assembly and function of whole tissues. Co
Externí odkaz:
https://doaj.org/article/ec2af9bd96934499a42ff5a2dff1b23c
Autor:
Ilenia Bernascone, Tamara González, Maria D. Barea, Claudia Carabaña, Mariam Hachimi, Minerva Bosch-Fortea, Silvia Santamaria, Raquel Martin, Julia Tarnick, Jose A. Garcia-Sanz, Fernando Martín-Belmonte
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The signalling pathways regulating how the mammary gland stroma interacts with the epithelia to then regulate gland development are unclear. Here, the authors identify Sfrp3 as regulating stroma communication via Wnts, on deletion, this increases duc
Externí odkaz:
https://doaj.org/article/c4d0a69819984d5cb45e409bbfe44df3
Publikováno v:
Seminars in Cell & Developmental Biology. 131:160-172
The Metazoan complexity arises from a primary building block, the epithelium, which comprises a layer of polarized cells that divide the organism into compartments. Most of these body compartments are organs formed by epithelial tubes that enclose an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3f09a8b6c8cb81184c7b6faa7adcf9
https://doi.org/10.1016/j.semcdb.2022.05.015
https://doi.org/10.1016/j.semcdb.2022.05.015
Publikováno v:
The Journal of cell biology. 221(5)
Epithelial cell morphology is essential for cellular homeostasis, but the mechanisms by which cell shape is established remain unclear. In this study, Marivin et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202111002) identify DAPLE as a linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c36653d786e439cad1da1c0cf0a9355
https://pubmed.ncbi.nlm.nih.gov/35389423
https://pubmed.ncbi.nlm.nih.gov/35389423
Autor:
Johannes Naß, Sophia N. Koerdt, Anja Biesemann, Tarek Chehab, Takao Yasuda, Mitsunori Fukuda, Fernando Martín-Belmonte, Volker Gerke
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(6)
Weibel–Palade bodies (WPB) are elongated, rod-like secretory organelles unique to endothelial cells that store the pro-coagulant von-Willebrand factor (VWF) and undergo regulated exocytosis upon stimulation with Ca2+- or cAMP-raising agonists. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e0d11d8971395197210acdd170e225
https://pubmed.ncbi.nlm.nih.gov/35660980
https://pubmed.ncbi.nlm.nih.gov/35660980
Publikováno v:
Dev Cell
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Force generation in epithelial tissues is often pulsatile, with actomyosin networks generating contractile forces before cyclically disassembling. This pulsed nature of cytoskeletal forces implies there must be ratcheting mechanisms that drive proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57153e80eae4ee864de052dafdd8f7b9
http://hdl.handle.net/10261/266253
http://hdl.handle.net/10261/266253
Autor:
Maria D. Barea, Minerva Bosch-Fortea, Mariam Hachimi, Claudia Carabaña, Raquel Martín, Jose A. Garcia-Sanz, Julia Tarnick, Tamara González, Fernando Martín-Belmonte, Ilenia Bernascone, Silvia Santamaría
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Mammary stroma is essential for epithelial morphogenesis and development. Indeed, postnatal mammary gland (MG) development is controlled locally by the repetitive and bi-directional cross-talk between the epithelial and the stromal compartment. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f6f121405193be3c302d999b52c723
http://link.springer.com/article/10.1038/s41467-019-10509-1
http://link.springer.com/article/10.1038/s41467-019-10509-1
Autor:
Maria D. Barea, Michel Bagnat, Gonzalo Herranz, Alejo E. Rodriguez-Fraticelli, Darren Gilmour, Catalina Grabowski, Gabriel Baonza, Silvia Campanario, Fernando Martín-Belmonte, Mariam Hachimi, Juan M. Serrador, Sergio Gomez-Lopez, Minerva Bosch-Fortea
Publikováno v:
Curr Biol
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The actin cortex is involved in many biological processes and needs to be significantly remodeled during cell differentiation. Developing epithelial cells construct a dense apical actin cortex to carry out their barrier and exchange functions. The ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7721c26b9b2f36c778e665d94ff17b8d
http://hdl.handle.net/10261/269000
http://hdl.handle.net/10261/269000
Publikováno v:
Methods in Molecular Biology ISBN: 9781071607787
Cells live in a highly curved and folded 3D microenvironment within the human body. Since epithelial cells in internal organs usually adopt a tubular shape, there is a need to engineer simple in vitro devices to promote this cellular configuration. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da37282b0308d9bdb33a1b22f0c10e6f
https://doi.org/10.1007/978-1-0716-0779-4_18
https://doi.org/10.1007/978-1-0716-0779-4_18