Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fernando M. Jabato"'
Autor:
Rafael Nuñez, Maria Jose Rodriguez, Francisca Palomares, Francisca Gomez, Fernando M. Jabato, Jose Cordoba-Caballero, Pedro Seoane, Jorge Losada, Javier Rojo, Maria Jose Torres, James Richard Perkins, Cristobalina Mayorga
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract To investigate food allergy-tolerance mechanisms induced through allergen-specific immunotherapy we used RNA-Sequencing to measure gene expression in lymph-node-derived dendritic cells from Pru p 3-anaphylactic mice after immunotherapy with
Externí odkaz:
https://doaj.org/article/080f354af3574613b987b4c16369fd74
Autor:
Elena Rojano, Fernando M. Jabato, James R. Perkins, José Córdoba-Caballero, Federico García-Criado, Ian Sillitoe, Christine Orengo, Juan A. G. Ranea, Pedro Seoane-Zonjic
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background Protein function prediction remains a key challenge. Domain composition affects protein function. Here we present DomFun, a Ruby gem that uses associations between protein domains and functions, calculated using multiple indices b
Externí odkaz:
https://doaj.org/article/04cbfecf2a7e4f32bcde7c8858ce38c0
Autor:
Fernando M. Jabato, José Córdoba-Caballero, Elena Rojano, Carlos Romá-Mateo, Pascual Sanz, Belén Pérez, Diana Gallego, Pedro Seoane, Juan A. G. Ranea, James R. Perkins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract High-throughput gene expression analysis is widely used. However, analysis is not straightforward. Multiple approaches should be applied and methods to combine their results implemented and investigated. We present methodology for the compre
Externí odkaz:
https://doaj.org/article/35510445a6824f5eb37caeaab2b029f1
Autor:
Elena Díaz-Santiago, Fernando M Jabato, Elena Rojano, Pedro Seoane, Florencio Pazos, James R Perkins, Juan A G Ranea
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009054 (2020)
Genetic and molecular analysis of rare disease is made difficult by the small numbers of affected patients. Phenotypic comorbidity analysis can help rectify this by combining information from individuals with similar phenotypes and looking for overla
Externí odkaz:
https://doaj.org/article/6dd3ee164edf4928a8b351983cede7ae
Autor:
Fernando M. Jabato, Florencio Pazos, Elena Rojano, Juan A. G. Ranea, James R. Perkins, Pedro Seoane, Adrián García Moreno, Monica Chagoyen
Publikováno v:
Human Genetics. 140:457-475
Copy number variation (CNV) related disorders tend to show complex phenotypic profiles that do not match known diseases. This makes it difficult to ascertain their underlying molecular basis. A potential solution is to compare the affected genomic re
Autor:
Carlos Romá-Mateo, James R. Perkins, Pedro Seoane, Belén Pérez, Juan A. G. Ranea, Elena Rojano, Diana Gallego, José Córdoba-Caballero, Fernando M. Jabato, Pascual Sanz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
instname
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
12 páginas, 7 figuras, 2 tablas. Te online version contains supplementary material available at https://doi.org/ 10.1038/s41598-021-94343-w . Code is available at the bioconductor landing page https://bioconductor.org/packages/ExpHunterSuite. Te lat
Autor:
James R. Perkins, Pedro Seoane, José Córdoba-Caballero, Manuel Manchado, M. Gonzalo Claros, Fernando M. Jabato
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Senegalese sole is an economically important flatfish species in aquaculture and an attractive model to decipher the molecular mechanisms governing the severe transformations occurring during metamorphosis, where retinoic acid seems to play a key rol
Autor:
Elena Rojano, Fernando M. Jabato, James R. Perkins, José Córdoba-Caballero, Federico García-Criado, Ian Sillitoe, Christine Orengo, Juan A. G. Ranea, Pedro Seoane-Zonjic
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-19 (2022)
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-19 (2022)
Background Protein function prediction remains a key challenge. Domain composition affects protein function. Here we present DomFun, a Ruby gem that uses associations between protein domains and functions, calculated using multiple indices based on t
Autor:
Florencio Pazos, Elena Rojano, Fernando M. Jabato, Elena Díaz-Santiago, James R. Perkins, Pedro Seoane, Juan A. G. Ranea
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009054 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Genetics
© 2020 Díaz-Santiago et al.
Genetic and molecular analysis of rare disease is made difficult by the small numbers of affected patients. Phenotypic comorbidity analysis can help rectify this by combining information from individuals with simila
Genetic and molecular analysis of rare disease is made difficult by the small numbers of affected patients. Phenotypic comorbidity analysis can help rectify this by combining information from individuals with simila
Publikováno v:
Bioinformatics and Biomedical Engineering ISBN: 9783030453848
IWBBIO
IWBBIO
Systemic approaches based on network analysis have been successful in associating pathological phenotypes observed in patients with their affected genomic regions. Previously we have used phenotype-genotype associations to determine the genetic cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1948bf87e56894a427f0aa4cd1fd74b
https://doi.org/10.1007/978-3-030-45385-5_69
https://doi.org/10.1007/978-3-030-45385-5_69