Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Fernando M Simabuco"'
Autor:
Annelize Z B Aragão, Marília Belloni, Fernando M Simabuco, Mariana R Zanetti, Sami Yokoo, Romênia R Domingues, Rebeca Kawahara, Bianca A Pauletti, Anderson Gonçalves, Michelle Agostini, Edgard Graner, Ricardo D Coletta, Jay W Fox, Adriana F Paes Leme
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43521 (2012)
The extracellular milieu is comprised in part by products of cellular secretion and cell surface shedding. The presence of such molecules of the sheddome and secretome in the context of the extracellular milieu may have important clinical implication
Externí odkaz:
https://doaj.org/article/29370448a80f4c2fb0209ca49354c931
Autor:
Luis G Morello, Patricia P Coltri, Alexandre J C Quaresma, Fernando M Simabuco, Tereza C L Silva, Guramrit Singh, Jeffrey A Nickerson, Carla C Oliveira, Melissa J Moore, Nilson I T Zanchin
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29174 (2011)
NIP7 is one of the many trans-acting factors required for eukaryotic ribosome biogenesis, which interacts with nascent pre-ribosomal particles and dissociates as they complete maturation and are exported to the cytoplasm. By using conditional knockdo
Externí odkaz:
https://doaj.org/article/0c8b645bff624901b06ad034d2eed274
Autor:
Luiz F Zerbini, Rodrigo E Tamura, Ricardo G Correa, Akos Czibere, Jason Cordeiro, Manoj Bhasin, Fernando M Simabuco, Yihong Wang, Xuesong Gu, Linglin Li, Devanand Sarkar, Jin-Rong Zhou, Paul B Fisher, Towia A Libermann
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24285 (2011)
Several epidemiological studies have correlated the use of non-steroidal anti-inflammatory drugs (NSAID) with reduced risk of ovarian cancer, the most lethal gynecological cancer, diagnosed usually in late stages of the disease. We have previously es
Externí odkaz:
https://doaj.org/article/7d842496b2984c239baf731100c80249
Autor:
Alisson L. da Rocha, Ana P. Pinto, Bruno L. S. Bedo, Gustavo P. Morais, Luciana C. Oliveira, Ruither O. G. Carolino, Jose R. Pauli, Fernando M. Simabuco, Leandro P. de Moura, Eduardo R. Ropelle, Dennys E. Cintra, Donato A. Rivas, Adelino S. R. da Silva
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The transcriptional repressor REV-ERB-α, encoded by Nuclear Receptor Subfamily 1 Group D Member 1 (Nr1d1), has been considered to play an essential role in the skeletal muscle oxidative capacity adaptation and muscle mass control. Also, thi
Externí odkaz:
https://doaj.org/article/44812d9e488248b9ad3a9c0506877951
Autor:
Ana P. Pinto, Vitor R. Muñoz, Alisson L. da Rocha, Rafael L. Rovina, Gustavo D. Ferrari, Luciane C. Alberici, Fernando M. Simabuco, Giovana R. Teixeira, José R. Pauli, Leandro P. de Moura, Dennys E. Cintra, Eduardo R. Ropelle, Ellen C. Freitas, Donato A. Rivas, Adelino S. R. da Silva
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interleukin 6 (IL-6) acts as a pro and anti-inflammatory cytokine, has an intense correlation with exercise intensity, and activates various pathways such as autophagy and mitochondrial unfolded protein response. Also, IL-6 is interconnected to circa
Externí odkaz:
https://doaj.org/article/c7e31ad4f3744cd9b15f46520e235d68
Autor:
Vitor R. Muñoz, Rafael C. Gaspar, Matheus B. Severino, Ana P. A. Macêdo, Fernando M. Simabuco, Eduardo R. Ropelle, Dennys E. Cintra, Adelino S. R. da Silva, Young-Bum Kim, José Rodrigo Pauli
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Physical exercise is considered a fundamental strategy in improving insulin sensitivity and glucose uptake in skeletal muscle. However, the molecular mechanisms underlying this regulation, primarily on skeletal muscle glucose uptake, are not fully un
Externí odkaz:
https://doaj.org/article/e425139095d144638760cc70c4c41a0e
Autor:
José R. Pauli, Vitor R. Muñoz, Renan Fudoli Lins Vieira, Susana C. B. R. Nakandakari, Ana Paula Azevêdo Macêdo, Robson Damasceno de Lima, Gabriel Calheiros Antunes, Fernando M. Simabuco, Adelino Sanchez Ramos da Silva, Leandro P. de Moura, Eduardo R. Ropelle, Dennys E. Cintra, Rania A. Mekary, Iman Zaghloul
Publikováno v:
Journal of Cellular Biochemistry. 124:520-532
Autor:
Rafael S. Brícola, André V. Cordeiro, Barbara M. Crisol, Renata R. Braga, Diego G. de Melo, Matheus B. Rocha, Rafael C. Gaspar, Susana C. B. R. Nakandakari, Vagner R. R. Silva, Chadi P. Anaruma, Carlos K. Katashima, Raphael D. S. Canciglieri, Vitor R. Munõz, Isadora C. B. Pavan, Ana P. Pinto, Fernando M. Simabuco, Adelino S. R. da Silva, Leandro P. Moura, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle
Publikováno v:
Cell Biochemistry and Function. 41:128-137
Dysfunction of the adipose tissue metabolism is considered as a significant hallmark of aging. It has been proposed that α-β hydrolase domain containing 5 (ABHD5) plays a critical role in the control of lipolysis. However, the role of ABHD5 in the
Autor:
Mariana C. S. Mancini, Ana P. Morelli, Matheus B. Severino, Isadora C. B. Pavan, Érika P. Zambalde, Mariana M. Góis, Luiz G. S. da Silva, Nathalia Quintero‐Ruiz, Caio F. Romeiro, Daniel F. G. dos Santos, Rosângela M. N. Bezerra, Fernando M. Simabuco
Publikováno v:
Journal of Cellular Biochemistry. 123:2079-2092
Prostate cancer (PCa) represents the second most common cancer in men and affects millions worldwide. Chemotherapy is a common treatment for PCa but the development of resistance is often a problem during therapy. NRF2 (nuclear factor erythroid 2-rel
Autor:
Bruno B. Marafon, Ana P. Pinto, Larissa G. de Vicente, Alisson L. da Rocha, Fernando M. Simabuco, Eduardo R. Ropelle, Leandro P. de Moura, Dennys E. Cintra, José R. Pauli, Adelino S. R. da Silva
Publikováno v:
Cell biochemistry and functionREFERENCES.
Many conditions, such as inflammation and physical exercise, can induce endoplasmic reticulum (ER) stress. Toll-like Receptor 4 (TLR4) can trigger inflammation and ER stress events. However, there are still no data in the literature regarding the rol