Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Fernando M Botelho"'
Autor:
Fernando M Botelho, Carla M T Bauer, Donna Finch, Jake K Nikota, Caleb C J Zavitz, Ashling Kelly, Kristen N Lambert, Sian Piper, Martyn L Foster, James J P Goldring, Jadwiga A Wedzicha, Jennifer Bassett, Jonathan Bramson, Yoichiro Iwakura, Matthew Sleeman, Roland Kolbeck, Anthony J Coyle, Alison A Humbles, Martin R Stämpfli
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28457 (2011)
Cigarette smoking is the main risk factor for the development of chronic obstructive pulmonary disease (COPD), a major cause of morbidity and mortality worldwide. Despite this, the cellular and molecular mechanisms that contribute to COPD pathogenesi
Externí odkaz:
https://doaj.org/article/a66704c4920d4a94bf3ed0aae0e515f7
Autor:
Carla M T Bauer, Caleb C J Zavitz, Fernando M Botelho, Kristen N Lambert, Earl G Brown, Karen L Mossman, John D Taylor, Martin R Stämpfli
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13251 (2010)
Chronic obstructive pulmonary disease is a progressive lung disease that is punctuated by periods of exacerbations (worsening of symptoms) that are attributable to viral infections. While rhinoviruses are most commonly isolated viruses during episode
Externí odkaz:
https://doaj.org/article/d3bda14c1f164ba0992658946530838d
Autor:
André L. D. Goneli, Paulo C. Corrêa, Acácio Figueiredo Neto, Michele R. H. Kirsch, Fernando M. Botelho
Publikováno v:
Engenharia Agrícola, Vol 40, Iss 2, Pp 184-191 (2020)
ABSTRACT Knowledge regarding the static pressure drop in granular layers is of fundamental importance in the development of efficient drying and aeration projects of agricultural products. Thus, the objective of this study was to evaluate the effects
Externí odkaz:
https://doaj.org/article/b2fa8e3ed071424c8d9de1c0fc37319f
Autor:
Steven P. Cass, Olivia Mekhael, Danya Thayaparan, Joshua J. C. McGrath, Spencer D. Revill, Matthew F. Fantauzzi, Peiyao Wang, Amir Reihani, Aaron I. Hayat, Christopher S. Stevenson, Anna Dvorkin-Gheva, Fernando M. Botelho, Martin R. Stämpfli, Kjetil Ask
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
RationaleThe accumulation of macrophages in the airways and the pulmonary interstitium is a hallmark of cigarette smoke-associated inflammation. Notably, pulmonary macrophages are not a homogenous population but consist of several subpopulations. To
Externí odkaz:
https://doaj.org/article/42863354dc984044af4890b5d31645bc
Autor:
Michele R. Hauth, Fernando M. Botelho, Renata H. Hoscher, Sílvia de C. C. Botelho, Gabriel H. H. de Oliveira
Publikováno v:
Engenharia Agrícola, Vol 38, Iss 4, Pp 590-598 (2018)
ABSTRACT The knowledge of physical properties of grains is important for the optimization of postharvest operations. Thus, this study aimed to evaluate the effect of moisture content over physical properties of different cultivars of soybean. Soybean
Externí odkaz:
https://doaj.org/article/2aedaa2148804e3384dfdd2947a2e28c
Autor:
Rex Park, Ashley Yip, Fernando M. Botelho, Anisha Dubey, Roland Kolbeck, Carl D. Richards, Allison Humbles, Ehab A. Ayaub
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2020 (2020)
Mediators of Inflammation, Vol 2020 (2020)
The interleukin-1 family member IL-33 participates in both innate and adaptive T helper-2 immune cell responses in models of lung disease. The IL-6-type cytokine Oncostatin M (OSM) elevates lung inflammation, Th2-skewed cytokines, alternatively activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9dc542df2068ac054cfbb696128681b
Autor:
Fernando M. Botelho, Carl D. Richards
Publikováno v:
Biomedicines
Oncostatin M (OSM), as one of the gp130/IL-6 family of cytokines, interacts with receptor complexes that include the gp130 signaling molecule and OSM receptor β OSMRβ chain subunits. OSMRβ chains are expressed relatively highly across a broad arra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfcaa14342af4b515315c100a5a8ab8
https://pubmed.ncbi.nlm.nih.gov/31817403
https://pubmed.ncbi.nlm.nih.gov/31817403
Autor:
Fernando M. Botelho, Dominik K. Fritz, Jessica Guerette, Steven Wong, Rebecca Rodrigues, Carl D. Richards
Publikováno v:
Cells
Volume 8
Issue 2
Cells, Vol 8, Iss 2, p 126 (2019)
Volume 8
Issue 2
Cells, Vol 8, Iss 2, p 126 (2019)
The accumulation of extracellular matrix in lung diseases involves numerous factors, including cytokines and chemokines that participate in cell activation in lung tissues and the circulation of fibrocytes that contribute to local fibrotic responses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699c707fd84d3c3acdf7d06176e6defb
Autor:
Mehrnoush Malek, Philip J. Devereaux, Jennie Johnstone, Jonathan L. Bramson, Melissa K. Andrew, Stephen D. Walter, Jamie Millar, Janet E. McElhaney, Mark Loeb, Shelly A. McNeil, Robin Parsons, Fernando M. Botelho, Ryan R. Brinkman, Tamas Fulop
Publikováno v:
Journal of the American Geriatrics Society. 65:153-159
Objectives To determine whether immune phenotypes associated with immunosenescence are predictive of frailty and mortality within 1-year in elderly nursing home residents. Design Cross sectional study of frailty; prospective cohort study of mortality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca7fd2c572c2cc161346f354363fa58
https://doi.org/10.1111/jgs.14507
https://doi.org/10.1111/jgs.14507
Publikováno v:
Cells
Volume 9
Issue 6
Cells, Vol 9, Iss 1338, p 1338 (2020)
Volume 9
Issue 6
Cells, Vol 9, Iss 1338, p 1338 (2020)
Resistin-like molecule alpha (RELM&alpha
) and YM-1 are secreted proteins implicated in murine models of alternatively activated macrophage (AA/M2) accumulation and Th2-skewed inflammation. Since the gp130 cytokine Oncostatin M (OSM) induces a T
) and YM-1 are secreted proteins implicated in murine models of alternatively activated macrophage (AA/M2) accumulation and Th2-skewed inflammation. Since the gp130 cytokine Oncostatin M (OSM) induces a T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7dac3721e7178db6064a6d312bced9
https://doi.org/10.3390/cells9061338
https://doi.org/10.3390/cells9061338