Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Fernando Laso-García"'
Autor:
Laura Casado-Fernández, Fernando Laso-García, Dolores Piniella, Mari Carmen Gómez-de Frutos, Laura Otero-Ortega, Susana-Belén Bravo, Blanca Fuentes-Gimeno, Félix Docando, Elisa Alonso-López, Gerardo Ruiz-Ares, Jorge Rodríguez-Pardo, Ricardo Rigual, Elena de Celis-Ruiz, Carlos Hervás, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, María Alonso de Leciñana
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106665- (2024)
Circulating extracellular vesicles (EVs) can participate in innate repair processes triggered after intracerebral hemorrhage (ICH). We aimed to describe changes in the proteomic profile of circulating EVs between the acute and subacute phases of ICH
Externí odkaz:
https://doaj.org/article/929b7e96181943e093d13df5522902db
Autor:
Mari Carmen Gómez-de Frutos, Fernando Laso-García, Iván García-Suárez, Dolores Piniella, Laura Otero-Ortega, Elisa Alonso-López, Javier Pozo-Novoa, Rebeca Gallego-Ruiz, Nerea Díaz-Gamero, Blanca Fuentes, María Alonso de Leciñana, Exuperio Díez-Tejedor, Gerardo Ruiz-Ares, María Gutiérrez-Fernández
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116834- (2024)
Although diabetes mellitus negatively affects post-ischaemic stroke injury and recovery, its impact on intracerebral haemorrhage (ICH) remains uncertain. This study aimed to investigate the effect of experimental diabetes (ED) on ICH-induced injury a
Externí odkaz:
https://doaj.org/article/45d086373bd449ffaefe9fd5fd305989
Autor:
Gabriel Torres Iglesias, MariPaz López-Molina, Lucía Botella, Fernando Laso-García, Beatriz Chamorro, Mireya Fernández-Fournier, Inmaculada Puertas, Susana B. Bravo, Elisa Alonso-López, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, Laura Otero-Ortega
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10761 (2024)
Multiple sclerosis (MS) remains the leading cause of neurological disability among young adults worldwide, underscoring the urgent need to define the best therapeutic strategy. Recent advances in proteomics have deepened our understanding of treatmen
Externí odkaz:
https://doaj.org/article/a0017b952dc7464eba9624b0166b620e
Autor:
Fernando Laso-García, Laura Casado-Fernández, Dolores Piniella, Mari Carmen Gómez-de Frutos, Jone Karmele Arizaga-Echebarria, María Pérez-Mato, Elisa Alonso-López, Laura Otero-Ortega, Susana Belén Bravo, María del Pilar Chantada-Vázquez, José Avendaño-Ortiz, Eduardo López-Collazo, María Isabel Lumbreras-Herrera, Angelo Gámez-Pozo, Blanca Fuentes, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, María Alonso de Leciñana
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 247-262 (2023)
Circulating extracellular vesicles (EVs) are proposed to participate in enhancing pathways of recovery after stroke through paracrine signaling. To verify this hypothesis in a proof-of-concept study, blood-derived allogenic EVs from rats and xenogeni
Externí odkaz:
https://doaj.org/article/0dea44d340794a8792650a0bea72d88a
Autor:
Gabriel Torres Iglesias, Mireya Fernández-Fournier, MariPaz López-Molina, Dolores Piniella, Fernando Laso-García, Mari Carmen Gómez-de Frutos, Elisa Alonso-López, Lucía Botella, Beatriz Chamorro, Sara Sánchez-Velasco, Inmaculada Puertas, Antonio Tallón Barranco, Pilar Nozal, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, Laura Otero-Ortega
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMultiple sclerosis is an inflammatory and demyelinating disease caused by a pathogenic immune response against the myelin sheath surfaces of oligodendrocytes. The demyelination has been classically associated with pathogenic B cells resid
Externí odkaz:
https://doaj.org/article/f1f70c3ff4ab4f559b60de1af29695b0
Autor:
Mireya Fernández-Fournier, MariPaz López-Molina, Gabriel Torres Iglesias, Lucía Botella, Beatriz Chamorro, Fernando Laso-García, Inmaculada Puertas, Antonio Tallón Barranco, Laura Otero-Ortega, Ana Frank-García, Exuperio Díez-Tejedor
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14192 (2023)
We aimed to analyze whether EVs carry antibodies against EBV antigens and the possibility that they could serve as diagnostic and disease activity blood biomarkers in RRMS. This was a prospective and observational study including patients with RRMS w
Externí odkaz:
https://doaj.org/article/31f2b72c20a5466cbb4cc5c36449996f
Autor:
Fernando Laso-García, Dolores Piniella, Mari Carmen Gómez-de Frutos, Laura Casado-Fernández, María Pérez-Mato, Elisa Alonso-López, Laura Otero-Ortega, Susana Belén Bravo, María Del Pilar Chantada-Vázquez, Lucía Trilla-Fuertes, Juan Ángel Fresno-Vara, Blanca Fuentes, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, María Alonso De Leciñana
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2023)
Introduction: Extracellular vesicles (EVs) participate in cell-to-cell paracrine signaling and can be biomarkers of the pathophysiological processes underlying disease. In intracerebral hemorrhage, the study of the number and molecular content of cir
Externí odkaz:
https://doaj.org/article/cfe4cf9972bb431eb60fc1e257a39c30
Autor:
Blanca Fuentes, Silvia Pastor-Yborra, Raquel Gutiérrez-Zúñiga, Noemí González-Pérez de Villar, Elena de Celis, Jorge Rodríguez-Pardo, Mari Carmen Gómez-de Frutos, Fernando Laso-García, María Gutiérrez-Fernández, MÁngeles Ortega-Casarrubios, Alfonso Soto, María López-Fernández, María Santamaría, Noemí Díez-González, Mar M. Freijo, Beatriz Zandio, Raquel Delgado-Mederos, Ana Calleja, Juan Carlos Portilla-Cuenca, Arturo Lisbona, Laura Otero-Ortega, Exuperio Díez-Tejedor
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-8 (2020)
Abstract Introduction Glycemic variability (GV) represents the amplitude of oscillations in glucose levels over time and is associated with higher mortality in critically ill patients. Our aim is to evaluate the impact of GV on acute ischemic stroke
Externí odkaz:
https://doaj.org/article/f9424f30335e4eeebc08ea1277d95d7f
Autor:
Elena de Celis-Ruiz, Blanca Fuentes, María Alonso de Leciñana, María Gutiérrez-Fernández, Alberto M. Borobia, Raquel Gutiérrez-Zúñiga, Gerardo Ruiz-Ares, Laura Otero-Ortega, Fernando Laso-García, Mari Carmen Gómez-de Frutos, Exuperio Díez-Tejedor
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Acute ischemic stroke is currently a major cause of disability despite improvement in recanalization therapies. Stem cells represent a promising innovative strategy focused on reduction of neurologic sequelae by enhancement of brain plasticity. We pe
Externí odkaz:
https://doaj.org/article/5332e02bcf39474a98482b9ebd625c94
Autor:
Laura Otero-Ortega, Fernando Laso-García, Mari Carmen Gómez-de Frutos, Luke Diekhorst, Arturo Martínez-Arroyo, Elisa Alonso-López, María Laura García-Bermejo, Macarena Rodríguez-Serrano, Mercedes Arrúe-Gonzalo, Exuperio Díez-Tejedor, Blanca Fuentes, María Gutiérrez-Fernández
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Mesenchymal stem cell-derived extracellular vesicles (EVs) are one of the most promising therapeutics in protective and/or regenerative therapy in animal models of stroke using a dose of 100 μg. However, whether EVs dose is relat
Externí odkaz:
https://doaj.org/article/3fe897b11bcf4a0fac4bf1ae968c9f3f