Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fernando Josa-Prado"'
Autor:
Inés Ripa, Sabina Andreu, Fernando Josa-Prado, Beatriz Fernández Gómez, Fernando de Castro, María Arribas, Raquel Bello-Morales, José Antonio López-Guerrero
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Herpes Simplex Virus type 1 (HSV-1) 1 is a neurotropic virus that has been associated with neurodegenerative disorders. The dysregulation of autophagy by HSV-1 has been proposed as a potential cause of neurodegeneration. While studies have extensivel
Externí odkaz:
https://doaj.org/article/91b99802dbc049d0872e1e4f2ca445a8
Autor:
Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz
Publikováno v:
eLife, Vol 12 (2023)
Paclitaxel (Taxol) is a taxane and a chemotherapeutic drug that stabilizes microtubules. While the interaction of paclitaxel with microtubules is well described, the lack of high-resolution structural information on a tubulin-taxane complex precludes
Externí odkaz:
https://doaj.org/article/ae0411d1a2f8477a839b678a56356407
Autor:
Juan Estévez-Gallego, Fernando Josa-Prado, Siou Ku, Ruben M Buey, Francisco A Balaguer, Andrea E Prota, Daniel Lucena-Agell, Christina Kamma-Lorger, Toshiki Yagi, Hiroyuki Iwamoto, Laurence Duchesne, Isabel Barasoain, Michel O Steinmetz, Denis Chrétien, Shinji Kamimura, J Fernando Díaz, Maria A Oliva
Publikováno v:
eLife, Vol 9 (2020)
Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for anti-tumor drugs. In MTs, GTP hydrolysis triggers structural changes in the lattice, which
Externí odkaz:
https://doaj.org/article/eb49d1e2fe6445b783e2a3c85b0c7bbb
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212857 (2019)
Protein SUMOylation regulates multiple processes involved in the differentiation and maturation of cells and tissues during development. Despite this, relatively little is known about the spatial and temporal regulation of proteins that mediate SUMOy
Externí odkaz:
https://doaj.org/article/dd9b6dd1317f4effab42febc6d7132ce
Autor:
Andrea E Prota, Daniel Lucena-Agell, Yuntao Ma, Juan Estevez-Gallego, Shuo Li, Katja Bargsten, Fernando Josa-Prado, Karl-Heinz Altmann, Natacha Gaillard, Shinji Kamimura, Tobias Mühlethaler, Federico Gago, Maria A Oliva, Michel O Steinmetz, Wei-Shuo Fang, J Fernando Díaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6031650b263dc281c6bcce2894cf2134
https://doi.org/10.7554/elife.84791.sa2
https://doi.org/10.7554/elife.84791.sa2
Autor:
Wei-Shuo Fang, Shinji Kamimura, Juan F. Giménez-Abián, María A. Oliva, Yun-Tao Ma, Juan Estévez-Gallego, J. Fernando Díaz, Andrea E. Prota, Daniel Lucena-Agell, Katja Bargsten, Kenneth Goossens, Shuo Li, José Manuel Andreu, Natacha Olieric, Carlos Roca, Michel O. Steinmetz, Tobias Mühlethaler, Ángeles Canales, Fernando Josa-Prado, Karl-Heinz Altmann
Paclitaxel (Taxol®) is a taxane and a first-line chemotherapeutic drug that stabilizes microtubules. While the interaction of paclitaxel with microtubules is well described, the current lack of high-resolution structural information on a tubulin-tax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bc20ec6d6b1ba8992558ceb43d8dba4
https://doi.org/10.1101/2021.07.20.453061
https://doi.org/10.1101/2021.07.20.453061
Autor:
Sabine Kienesberger, Maksym Kitsera, Ronald A. Glabonjat, Jakob Pletz, Stefan Schild, José Fernando Díaz, Isabel Barasoain, Daniel Lucena, Joanna I. Loizou, Georg Schneditz, Rolf Breinbauer, Ellen L. Zechner, Lisa Pöltl, Katrin Unterhauser, Christian Lembacher-Fadum, Fernando Josa-Prado, Elisabeth Dornisch, Marc Wiedner, Wolfgang Kroutil, Gregor Gorkiewicz, Sandro Roier, Christoph Högenauer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
10 p.-6 fig.
Establishing causal links between bacterial metabolites and human intestinal disease is a significant challenge. This study reveals the molecular basis of antibiotic-associated hemorrhagic colitis (AAHC) caused by intestinal residen
Establishing causal links between bacterial metabolites and human intestinal disease is a significant challenge. This study reveals the molecular basis of antibiotic-associated hemorrhagic colitis (AAHC) caused by intestinal residen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3208ade831a4ea76067a72009476607
https://doi.org/10.1073/pnas.1819154116
https://doi.org/10.1073/pnas.1819154116
Autor:
J. Alberto Marco, Eva Falomir, Alberto Pla, J. Fernando Díaz, Celia Martín-Beltrán, Fernando Josa-Prado, Juan Murga, Raül Agut, Raquel Gil-Edo, Miguel Carda
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
11 p.-9 fig.-4 tab.
Background: Six N-acyl derivatives of aminocombretastatin A-4 have been synthesized and evaluated according to their interaction with tubulin and as c-Myc downregulators.
Aims: In search of new promising anti-cancer agen
Background: Six N-acyl derivatives of aminocombretastatin A-4 have been synthesized and evaluated according to their interaction with tubulin and as c-Myc downregulators.
Aims: In search of new promising anti-cancer agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e589f42d518cfa688d0f8c7dd8cbf0f
https://pubmed.ncbi.nlm.nih.gov/33222678
https://pubmed.ncbi.nlm.nih.gov/33222678
Autor:
Isabel García-Álvarez, E. M. Medina-Rodríguez, Leoncio Garrido, Jesús Pastor, Ana Bribián, Verónica Murcia-Belmonte, Pedro F. Esteban, Lorena Vega-Zelaya, Fernando Josa-Prado, Isabel Machín-Díaz, Fernando de Castro
Publikováno v:
Journal of Clinical Medicine
DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
Universidad Francisco de Vitoria
Journal of Clinical Medicine, Vol 9, Iss 1681, p 1681 (2020)
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
Digital.CSIC. Repositorio Institucional del CSIC
Volume 9
Issue 6
DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
Universidad Francisco de Vitoria
Journal of Clinical Medicine, Vol 9, Iss 1681, p 1681 (2020)
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname
Digital.CSIC. Repositorio Institucional del CSIC
Volume 9
Issue 6
This article belongs to the Special Issue Glial Cells in Central Nervous System (CNS) Pathology and Repair.
Besides giving rise to oligodendrocytes (the only myelin-forming cell in the Central Nervous System (CNS) in physiological conditions), O
Besides giving rise to oligodendrocytes (the only myelin-forming cell in the Central Nervous System (CNS) in physiological conditions), O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a512779d52c7cbb73624640afa6ad6f
http://europepmc.org/articles/PMC7355819
http://europepmc.org/articles/PMC7355819
Autor:
Isabel Barasoain, Andrea E. Prota, J. Fernando Díaz, Francisco de Asís Balaguer, Christina Kamma-Lorger, Siou Ku, María A. Oliva, Rubén M. Buey, Toshiki Yagi, Laurence Duchesne, Denis Chrétien, Daniel Lucena-Agell, Shinji Kamimura, Juan Estévez-Gallego, Michel O. Steinmetz, Hiroyuki Iwamoto, Fernando Josa-Prado
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2020, 9, pp.e50155. ⟨10.7554/eLife.50155⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
'eLife ', vol: 9, pages: e50155-1-e50155-26 (2020)
eLife, Vol 9 (2020)
eLife, 2020, 9, pp.e50155. ⟨10.7554/eLife.50155⟩
eLife, eLife Sciences Publication, 2020, 9, pp.e50155. ⟨10.7554/eLife.50155⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
'eLife ', vol: 9, pages: e50155-1-e50155-26 (2020)
eLife, Vol 9 (2020)
eLife, 2020, 9, pp.e50155. ⟨10.7554/eLife.50155⟩
26 p.-5 fig.-5 tab.
Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for anti-tumor drugs. In MTs, GTP hydrolysis triggers structural chan
Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for anti-tumor drugs. In MTs, GTP hydrolysis triggers structural chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f00c01fd31baf004ef430cbc4a55d6
https://hal.archives-ouvertes.fr/hal-02552246/file/hal-02552246.pdf
https://hal.archives-ouvertes.fr/hal-02552246/file/hal-02552246.pdf