Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fernando Hernández-Borja"'
Autor:
Samuel Estrada-Soto, Soledad Alemán-Pantitlán, Emmanuel Gaona-Tovar, Fernando Hernández-Borja, Yolanda Alcaraz, Rafael Villalobos-Molina, Miguel A. Vázquez
Publikováno v:
Drugs and Drug Candidates, Vol 3, Iss 2, Pp 342-352 (2024)
Derivatives of 4H-pyrans and 1,6-dihydropyridines have generated considerable attention due to their interesting biological and therapeutic values. Their pharmacological activities include vasorelaxant, anticarcinogenic, antimicrobial, and antioxidan
Externí odkaz:
https://doaj.org/article/2bd157d9221e410c8337dec8f05bf936
Autor:
MiguelA. Vázquez, Rafael Villalobos-Molina, Samuel Estrada-Soto, Priscila Rendón-Vallejo, Emanuel Hernández-Núñez, Fernando Hernández-Borja, César Millán-Pacheco
Publikováno v:
Drug research. 72(1)
Several 4H-pyran derivatives were designed and synthesized previously as vasorelaxant agents for potential antihypertensive drugs. In this context, the objective of the present investigation was to determine the functional mechanism of vasorelaxant a
Autor:
Itzel Mercado-Sánchez, David Ordaz-Rosado, Clarisa Villegas Gómez, Miguel A. Vázquez, Fernando Hernández-Borja, Marco A. García-Revilla, Yolanda Alcaraz, Rocío García-Becerra, Nancy Santos-Martínez
Publikováno v:
Daru
PURPOSE: Histone deacetylases (HDACs) play a vital role in the epigenetic regulation of gene expression due to their overexpression in several cancer forms. Therefore, these enzymes are considered as a potential anticancer drug target. Different synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a644db3de9ca3051237a52685d42a433
https://europepmc.org/articles/PMC8602590/
https://europepmc.org/articles/PMC8602590/
Autor:
Fernando Hernández-Borja, Leticia Contreras, Julio López, David Cruz Cruz, Samuel Estrada-Soto, Francisco Delgado, Miguel A. Vázquez, Yolanda Alcaraz
Publikováno v:
Synthesis. 50:1020-1026
In this study, a molecular hybridization strategy was used to design and synthesize two novel series of hybrid compounds: 4H-pyran-lipoic and 4H-pyran-azetidine, employing ammonium hydroxide and involving the participation of aldehydes, malononitrile