Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Fernando Gómez‐Pinilla"'
Autor:
Russell Littman, Zachary Hemminger, Robert Foreman, Douglas Arneson, Guanglin Zhang, Fernando Gómez‐Pinilla, Xia Yang, Roy Wollman
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 6, Pp 1-15 (2021)
Abstract RNA hybridization‐based spatial transcriptomics provides unparalleled detection sensitivity. However, inaccuracies in segmentation of image volumes into cells cause misassignment of mRNAs which is a major source of errors. Here, we develop
Externí odkaz:
https://doaj.org/article/f5d90bb73be44dc190803938684da5fa
Autor:
Pavan Thapak, Fernando Gomez-Pinilla
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107389- (2024)
Mitochondria provide the energy to keep cells alive and functioning and they have the capacity to influence highly complex molecular events. Mitochondria are essential to maintain cellular energy homeostasis that determines the course of neurological
Externí odkaz:
https://doaj.org/article/5b6e647e4b974e208b8a87dbdcb2b98f
Autor:
Yingxi Wu, Haijian Wu, Jianxiong Zeng, Brock Pluimer, Shirley Dong, Xiaochun Xie, Xinying Guo, Tenghuan Ge, Xinyan Liang, Sudi Feng, Youzhen Yan, Jian‑Fu Chen, Naomi Sta Maria, Qingyi Ma, Fernando Gomez‑Pinilla, Zhen Zhao
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/76420be6b19747b58a2a2edbb3cdf4be
Autor:
Fernando Gómez-Pinilla
Publikováno v:
Traumatic Brain Injury ISBN: 9781315371351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7d3dc5502b046fb5c2b8078e86ae7c6
https://doi.org/10.1201/9781315371351-8
https://doi.org/10.1201/9781315371351-8
Publikováno v:
Sports Medicine and Health Science, Vol 4, Iss 3, Pp 147-151 (2022)
Physical rehabilitation is an effective therapy to normalize weaknesses encountered with neurological disorders such as traumatic brain injury (TBI). However, the efficacy of exercise is limited during the acute period of TBI because of metabolic dys
Externí odkaz:
https://doaj.org/article/c63155972aa24fd0bf75b457b256612f
Autor:
Yingxi Wu, Haijian Wu, Jianxiong Zeng, Brock Pluimer, Shirley Dong, Xiaochun Xie, Xinying Guo, Tenghuan Ge, Xinyan Liang, Sudi Feng, Youzhen Yan, Jian-Fu Chen, Naomi Sta Maria, Qingyi Ma, Fernando Gomez-Pinilla, Zhen Zhao
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Introduction Traumatic brain injury (TBI) is considered as the most robust environmental risk factor for Alzheimer’s disease (AD). Besides direct neuronal injury and neuroinflammation, vascular impairment is also a hallmark event of the pa
Externí odkaz:
https://doaj.org/article/04442ec56532420296d3f765e114271d
Publikováno v:
Journal of neuroscience research. 76(3)
To assess the relationship between brain-derived neurotrophic factor (BDNF) and synapsin I in the hippocampus during exercise, we employed a novel microsphere injection method to block the action of BDNF through its tyrosine kinase (Trk) receptor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23d39b6177dfedb9c355022afd25016b
https://pubmed.ncbi.nlm.nih.gov/15079864
https://pubmed.ncbi.nlm.nih.gov/15079864
Publikováno v:
The European journal of neuroscience. 16(6)
Studies were performed to determine the effects of acute and chronic voluntary periods of exercise on the expression of hippocampal genes. RNAs from rodents exposed to a running wheel for 3, 7 and 28 days were examined using a microarray with 1176 cD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ea8695d9cb045330e061c27b5b6664d
https://pubmed.ncbi.nlm.nih.gov/12383240
https://pubmed.ncbi.nlm.nih.gov/12383240
Publikováno v:
Journal of neuroscience research. 69(1)
Sanfilippo syndrome type B (MPS III B) is a neurodegenerative disorder characterized by profound mental retardation and early death. It is caused by deficiency of a lysosomal enzyme involved in heparan sulfate (HS) degradation. Because HS accumulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ad0636af629750812ff542b751d1388
https://pubmed.ncbi.nlm.nih.gov/12111813
https://pubmed.ncbi.nlm.nih.gov/12111813
Autor:
Richard J. Johnson, Fernando Gomez-Pinilla, Maria Nagel, Takahiko Nakagawa, Bernardo Rodriguez-Iturbe, Laura G. Sanchez-Lozada, Dean R. Tolan, Miguel A. Lanaspa
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
The loss of cognitive function in Alzheimer’s disease is pathologically linked with neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral insulin resistance and mitochondrial dysfunction have emerged as important
Externí odkaz:
https://doaj.org/article/86a7205a3dfa48758dcc21f7e9d434e1