Zobrazeno 1 - 10
of 674
pro vyhledávání: '"Fernando Ferreira, Costa"'
Autor:
Ana Carolina Mourão Toreli, Isabella Toni, Dulcinéia Martins de Albuquerque, Carolina Lanaro, Jersey Heitor Maues, Kleber Yotsumoto Fertrin, Paula de Melo Campos, Fernando Ferreira Costa
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S197-S200 (2024)
Background: Iron overload (IO) is a complex condition in which clinical, behavioral and genetic factors contribute to the phenotype. In multiethnic and non-Caucasian populations, mutations in HFE gene alone cannot explain IO in most of the cases, and
Externí odkaz:
https://doaj.org/article/5632ab1b001842aba25183d991e420a3
Autor:
Pedro Junqueira Fleury Silva, Caroline Martins Silva, Brunno Machado de Campos, Paula deMelo Campos, Samuel deSouza Medina, Andreza Lamonica, José Vitor Coimbra Trindade, Fernando Cendes, Fernando Ferreira Costa, Sara Teresinha Olalla Saad, Bruno Deltreggia Benites
Publikováno v:
eJHaem, Vol 5, Iss 2, Pp 308-315 (2024)
Abstract Sickle cell disease (SCD) patients are at higher risk of developing silent cerebral infarcts and overt stroke, which may reflect cognitive impairment, functional limitations, and worse quality of life. The cognitive function of Brazilian adu
Externí odkaz:
https://doaj.org/article/4341f61b1fb6415ca9c81a399b79785e
Autor:
Sueli Matilde da Silva Costa, Mirta Tomie Ito, Pedro Rodrigues Sousa da Cruz, Bruno Batista De Souza, Vinicius Mandolesi Rios, Victor de Haidar e Bertozzo, Ana Carolina Lima Camargo, Marina Gonçalves Monteiro Viturino, Carolina Lanaro, Dulcinéia Martins de Albuquerque, Amanda Morato do Canto, Sara Teresinha Olalla Saad, Stephanie Ospina-Prieto, Margareth Castro Ozelo, Fernando Ferreira Costa, Mônica Barbosa de Melo
Publikováno v:
Experimental Biology and Medicine, Vol 249 (2024)
HbSC disease, a less severe form of sickle cell disease, affects the retina more frequently and patients have higher rates of proliferative retinopathy that can progress to vision loss. This study aimed to identify differences in the expression of en
Externí odkaz:
https://doaj.org/article/fa1706a357894d4bbcbdf5ba1859ce6d
Autor:
Tammyris Helena Rebecchi e Silveira, Dalila Andrade Pereira, Danillo Andrade Pereira, Fabiano Beraldi Calmasini, Arthur L. Burnett, Fernando Ferreira Costa, Fábio Henrique Silva
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Patients with sickle cell disease (SCD) display an overactive bladder (OAB). Intravascular hemolysis in SCD is associated with various severe SCD complications. However, no experimental studies have evaluated the effect of intravascular hemolysis on
Externí odkaz:
https://doaj.org/article/377ef508940f48bcb8b9bf76a2177311
Autor:
Tammyris Helena Rebecchi Silveira, Fabiano Beraldi Calmasini, Mariana Gonçalves de Oliveira, Fernando Ferreira Costa, Fábio Henrique Silva
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Men with sickle cell disease (SCD) frequently experience priapism, defined as prolonged, painful erections occurring without sexual arousal or desire. This urological emergency can lead to penile fibrosis and permanent erectile dysfunction if not tre
Externí odkaz:
https://doaj.org/article/dd42fadff5be445ca88bea96451aa706
Autor:
Adekunle Emmanuel Alagbe, Gisele Audrei Pedroso, Beatriz Benedetti de Oliveira, Edivilson da Costa, Gisélia Aparecida Freire Maia, Bruna Facanali Piellusch, Susan Elisabeth Domingues Costa Jorge, Fernando Ferreira Costa, José Luiz Proença Modena, Angelica Zaninelli Schreiber, Maria de Fátima Sonati, Magnun Nueldo Nunes Santos
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss 1, Pp 14-21 (2024)
Introduction: The hemogram and hemogram-derivative ratios (HDRs) are becoming markers of the severity and mortality of COVID-19. We evaluated the hemograms and serial weekly HDRs [neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), pl
Externí odkaz:
https://doaj.org/article/5ae5a371a1b94ac59205079d3c6eada3
Autor:
Dalila Andrade Pereira, Danillo Andrade Pereira, Pamela da Silva Pereira, Tammyris Helena Rebecchi Silveira, Fabiano Beraldi Calmasini, Leonardo Oliveira Reis, Fernando Ferreira Costa, Fábio Henrique Silva
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292706 (2023)
Sickle cell disease (SCD) is a genetic disorder that has been associated with priapism. The role of hydroxyurea, a common SCD therapy, in influencing the nitric oxide (NO)-cGMP pathway and its effect on priapism is unclear. To investigate the effect
Externí odkaz:
https://doaj.org/article/a8d282b6d2cc47c49fd214eb15197b33
Autor:
Rodolfo D. Cançado, Aderson da Silva Araújo, Alex Freire Sandes, Celso Arrais, Clarisse Lopes de Castro Lobo, Maria Stella Figueiredo, Sandra Fátima Menosi Gualandro, Sara Teresinha Olalla Saad, Fernando Ferreira Costa
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 43, Iss 3, Pp 341-348 (2021)
Paroxysmal nocturnal hemoglobinuria is a chronic, multi-systemic, progressive and life-threatening disease characterized by intravascular hemolysis, thrombotic events, serious infections and bone marrow failure. Paroxysmal nocturnal hemoglobinuria re
Externí odkaz:
https://doaj.org/article/d0c651cc3b40439ba8584c9d32114b52
Autor:
Pamela da Silva Pereira, Dalila Andrade Pereira, Fabiano Beraldi Calmasini, Leonardo O. Reis, Nathan Brinkman, Arthur L. Burnett, Fernando Ferreira Costa, Fábio Henrique Silva
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: In sickle cell disease (SCD), reduced bioavailability of endothelial NO and cGMP results in reduced expression of phosphodiesterase type 5 (PDE5), thus impairing the penile erection control mechanism and resulting in prolonged penile erec
Externí odkaz:
https://doaj.org/article/97a1aed1fb2640a7a30ac134e1540622
Autor:
Bidossessi Wilfried Hounkpe, Francine Chenou, Igor de Farias Domingos, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson S. Araujo, Antonio Roberto Lucena‐Araújo, Pedro Vieira da Silva Neto, Adriana Malheiro, Nelson Abrahim Fraiji, Fernando Ferreira Costa, Marcos André C. Bezerra, Magnun Nueldo Nunes Santos, Erich Vinicius De Paula
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 204-210 (2021)
Abstract Background Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD). NET
Externí odkaz:
https://doaj.org/article/7a2ac59c8d2740c2896aa4fa58dc8a97