Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Fernando E, Figueroa"'
Autor:
Angela C. Court, Eliseo Parra-Crisóstomo, Pablo Castro-Córdova, Luiza Abdo, Emmanuel Arthur Albuquerque Aragão, Rocío Lorca, Fernando E. Figueroa, Martín Hernán Bonamino, Maroun Khoury
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Apoptosis, a form of programmed cell death, is critical for the development and homeostasis of the immune system. Chimeric antigen receptor T (CAR-T) cell therapy, approved for hematologic cancers, retains several limitations and
Externí odkaz:
https://doaj.org/article/d0d64939ef1b4ab188402484e84e7de2
Autor:
Sandra Villanueva, Fernando González, Eduardo Lorca, Andrés Tapia, Valentina G López, Rocío Strodthoff, Francisca Fajre, Juan E. Carreño, Ricardo Valjalo, César Vergara, Manuel Lecanda, Jorge Bartolucci, Fernando E. Figueroa, Maroun Khoury
Publikováno v:
Kidney Research and Clinical Practice, Vol 38, Iss 2, Pp 176-185 (2019)
Background : Chronic kidney disease (CKD) is a growing public health concern, and available treatments are insufficient in limiting disease progression. New strategies, including regenerative cell-based therapies, have emerged as therapeutic alternat
Externí odkaz:
https://doaj.org/article/72e580c5667344079f1c5812ca1c88bd
Autor:
Mónica Kurte, Patricia Luz-Crawford, Ana María Vega-Letter, Rafael A. Contreras, Gautier Tejedor, Roberto Elizondo-Vega, Luna Martinez-Viola, Catalina Fernández-O’Ryan, Fernando E. Figueroa, Christian Jorgensen, Farida Djouad, Flavio Carrión
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The therapeutic effect of mesenchymal stem cells (MSCs) in multiple sclerosis (MS) and the experimental autoimmune encephalomyelitis (EAE) model has been well described. This effect is, in part, mediated through the inhibition of IL17-producing cells
Externí odkaz:
https://doaj.org/article/7631002176d64128a6e81663cbd569b2
Autor:
Ana María Ávalos, Felipe A Apablaza, Mariana Quiroz, Viviana Toledo, Juan Pedro Peña, Luis Michea, Carlos E Irarrazabal, Flavio A Carrión, Fernando E Figueroa
Publikováno v:
Biological Research, Vol 45, Iss 2, Pp 193-200 (2012)
Th17 cells, a recently described subtype of CD4+ effector lymphocytes, have been linked to cell-mediated autoimmune and inflammatory diseases as well as to cardiovascular diseases. However, the participation of IL-17A in myocardial ischemic injury ha
Externí odkaz:
https://doaj.org/article/69ef782e85674ea2ab896db3cc0bca3d
Publikováno v:
Biological Research, Vol 45, Iss 3, Pp 269-277 (2012)
Mesenchymal stem cells (MSCs) are now known to display not only stem cell multipotency, but also robust antiinflammatory and regenerative properties. After widespread in-vitro and in-vivo preclinical testing, autologous and allogeneic MSCs have been
Externí odkaz:
https://doaj.org/article/ee19ab4cba744d9980e4a8270fa58dcc
Autor:
Mónica Kurte, Javiera Bravo-Alegría, Alexander Torres, Vania Carrasco, Cristina Ibáñez, Ana María Vega-Letter, Catalina Fernández-O’Ryan, Carlos E. Irarrázabal, Fernando E. Figueroa, Rodrigo A. Fuentealba, Claudia Riedel, Flavio Carrión
Publikováno v:
Stem Cells International, Vol 2015 (2015)
Potent immunosuppressive and regenerative properties of mesenchymal stem cells (MSCs) position them as a novel therapy for autoimmune diseases. This research examines the therapeutic effect of MSCs administration at different disease stages in experi
Externí odkaz:
https://doaj.org/article/fe5da1fb37a24073bcfaaec3d0839bad
Autor:
Ricardo Valjalo, Eduardo Lorca, Fernando E Figueroa, Juan Carreno, Jorge Bartolucci, Andrés Tapia, Maroun Khoury, Sandra Villanueva, Rocío Strodthoff, Francisca Fajre, Manuel Lecanda, César Vergara, Valentina G López, Fernando González
Publikováno v:
Kidney Research and Clinical Practice, Vol 38, Iss 2, Pp 176-185 (2019)
Kidney Research and Clinical Practice
Kidney Research and Clinical Practice
Background : Chronic kidney disease (CKD) is a growing public health concern, and available treatments are insufficient in limiting disease progression. New strategies, including regenerative cell-based therapies, have emerged as therapeutic alternat
Autor:
Maroun Khoury, Fernando E Figueroa
Publikováno v:
Gene Therapy. 27:2-5
Rigorous testing of cell therapies in South America struggles with emerging opportunities and regulatory deficiencies. As in other continents, these tend to be permissive with commercial opportunism but stifling for research. We describe a successful
Autor:
Patricia Luz-Crawford, Luis Federico Bátiz, E. Parra, Maroun Khoury, Fernando E Figueroa, Mónica Kurte, Rafael Contreras, Vinicius Maracaja-Coutinho, Alice Le-Gatt, Angela C Court, Roberto Elizondo-Vega, María Ignacia Ortúzar, Victor Aliaga-Tobar, Karina Pino-Lagos
Publikováno v:
Publons
EMBO Rep
EMBO Rep
Mesenchymal stem cells (MSCs) have fueled ample translation for the treatment of immune‐mediated diseases. They exert immunoregulatory and tissue‐restoring effects. MSC‐mediated transfer of mitochondria (MitoT) has been demonstrated to rescue t
Autor:
Pablo Pedreros, Rubén Lamich, Ema Abarzua, Francisca Alcayaga-Miranda, Paz Gonzalez, Fernando J. Verdugo, Jorge Bartolucci, Amit N. Patel, Maroun Khoury, Iván Palma, Gloria Valdivia, Carolina Nazzal, Matthew Brobeck, Jimena Cuenca, Ricardo Larrea, Valentina M. Lopez, Fernando E Figueroa, Carlos Goset, Pamela Rojo
Publikováno v:
Circulation Research
Supplemental Digital Content is available in the text.
Rationale: Umbilical cord–derived mesenchymal stem cells (UC-MSC) are easily accessible and expanded in vitro, possess distinct properties, and improve myocardial remodeling and function i
Rationale: Umbilical cord–derived mesenchymal stem cells (UC-MSC) are easily accessible and expanded in vitro, possess distinct properties, and improve myocardial remodeling and function i