Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Fernando Durães"'
Autor:
Diana I. S. P. Resende, Fernando Durães, Sidika Zubarioglu, Joana Freitas-Silva, Nikoletta Szemerédi, Madalena Pinto, Eugénia Pinto, Paulo Martins da Costa, Gabriella Spengler, Emília Sousa
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 209 (2024)
Global health faces a significant issue with the rise of infectious diseases caused by bacteria, fungi, viruses, and parasites. The increasing number of multi-drug resistant microbial pathogens severely threatens public health worldwide. Antibiotic-r
Externí odkaz:
https://doaj.org/article/2c95e70dd07d42b88d028f4c8d9b3104
Autor:
Francisca Carvalhal, Ana Cristina Magalhães, Rita Rebelo, Andreia Palmeira, Diana I. S. P. Resende, Fernando Durães, Miguel Maia, Cristina P. R. Xavier, Luísa Pereira, Emília Sousa, Marta Correia-da-Silva, M. Helena Vasconcelos
Publikováno v:
Molecules, Vol 28, Iss 20, p 7204 (2023)
The spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relies on host cell surface glycans to facilitate interaction with the angiotensin-converting enzyme 2 (ACE-2) receptor. This interaction between ACE2 and the spike
Externí odkaz:
https://doaj.org/article/6bef8e98d0454966af5953e202ac2770
Autor:
Mariana C. Almeida, Nikoletta Szemerédi, Fernando Durães, Solida Long, Diana I. S. P. Resende, Paulo Martins da Costa, Madalena Pinto, Gabriella Spengler, Emília Sousa
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 922 (2023)
Drug resistance is rising to alarming levels, constituting one of the major threats to global health. The overexpression of efflux pumps and the formation of biofilms constitute two of the most common resistance mechanisms, favoring the virulence of
Externí odkaz:
https://doaj.org/article/887c16dec5c64af9894bd3da2b4296c3
Autor:
Mariana C. Almeida, Nikoletta Szemerédi, Fernando Durães, Diana I. S. P. Resende, Paulo Martins da Costa, Madalena Pinto, Gabriella Spengler, Emília Sousa
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 43 (2022)
With antimicrobial resistance reaching critical levels worldwide, the development of new compounds that are effective against resistant bacterial pathogens or that can potentiate the effect of known antibiotics is an urgent need. The formation of bio
Externí odkaz:
https://doaj.org/article/ec5c025f1f5d425aaeb55f1339e20a27
Autor:
Joana Cardoso, Joana Freitas-Silva, Fernando Durães, Madalena Pinto, Emília Sousa, Eugénia Pinto
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 46 (2022)
Systemic fungal infections caused by filamentous fungi, particularly in the immunocompromised population, represent a serious threat to public health. The increase in resistant strains to classic antifungal drugs, especially azoles, is a global healt
Externí odkaz:
https://doaj.org/article/962acf9e557846f98245c959008e6d3c
Autor:
Ana Jesus, Fernando Durães, Nikoletta Szemerédi, Joana Freitas-Silva, Paulo Martins Costa, Eugénia Pinto, Madalena Pinto, Gabriella Spengler, Emília Sousa, Honorina Cidade
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 68 (2022)
The effective response of antibiotics is threatened by the proliferation of micro-organisms that manifest resistance mechanisms, leading to an increase of progressively untreatable infectious diseases around the world. One solution to this problem co
Externí odkaz:
https://doaj.org/article/c38fd0246cff49ce9111f0278e2027a8
Autor:
Daniela Pereira, Fernando Durães, Nikoletta Szemerédi, Joana Freitas-da-Silva, Eugénia Pinto, Paulo Martins-da-Costa, Madalena Pinto, Marta Correia-da-Silva, Gabriella Spengler, Emília Sousa, Honorina Cidade
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14291 (2022)
Resistance to antibiotics is an emerging problem worldwide, which leads to an increase in morbidity and mortality rates. Several mechanisms are attributed to bacterial resistance, overexpression of efflux pumps being one of the most prominent. As an
Externí odkaz:
https://doaj.org/article/1c35a56d73024d3589d3a904f31377f6
Autor:
Ana Rita Neves, Fernando Durães, Joana Freitas-Silva, Nikoletta Szemerédi, Paulo Martins-da-Costa, Eugénia Pinto, Marta Correia-da-Silva, Gabriella Spengler, Emília Sousa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14468 (2022)
The overexpression of efflux pumps is one of the strategies used by bacteria to resist antibiotics and could be targeted to circumvent the antibiotic crisis. In this work, a series of trimethoxybenzoic acid derivatives previously described as antifou
Externí odkaz:
https://doaj.org/article/a07751b8ba6b4554be3822b0d6c29718
Autor:
Joana Cardoso, Joana Freitas-Silva, Fernando Durães, Diogo Teixeira Carvalho, Luís Gales, Madalena Pinto, Emília Sousa, Eugénia Pinto
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1488 (2022)
Fungal infections are one of the main causes of mortality and morbidity worldwide and taking into account the increasing incidence of strains resistant to classical antifungal drugs, the development of new agents has become an urgent clinical need. C
Externí odkaz:
https://doaj.org/article/d40f753d48ef4ff7bdae45a45c72545b
Autor:
Ana Jesus, Fernando Durães, Nikoletta Szemerédi, Joana Freitas-Silva, Paulo Martins da Costa, Eugénia Pinto, Madalena Pinto, Gabriella Spengler, Emília Sousa, Honorina Cidade
Publikováno v:
Marine Drugs, Vol 20, Iss 5, p 315 (2022)
The growing number of infectious diseases around the world threatens the effective response of antibiotics, contributing to the increase in antibiotic resistance seen as a global health problem. Currently, one of the main challenges in antimicrobial
Externí odkaz:
https://doaj.org/article/0809e97d96c5425baabaeaf2136bcd34