Výsledky vyhledávání - "Fernando Carvajal-Borda"

Abstract 6593: PRGN-3005 UltraCAR-T™: multigenic CAR-T cells generated using non-viral gene delivery and rapid manufacturing process for the treatment of ovarian cancer

Autor: Padma Kamineny, Simon Metenou, Adeline Govekung, Marion Chakiath, Jose Velez, Shah Rutul R, Tim Chan, Jacques Plummer, Fernando Carvajal-Borda, Helen Sabzevari, Carol Poortman, Xiaohong Ma, Mary L. Disis, Lindsey Shepard

Publikováno v: Cancer Research. 80:6593-6593

Ovarian cancer is the most lethal of gynecologic cancers. Chimeric antigen receptor (CAR)-T cells have improved clinical outcomes in hematological malignancies; however similar responses have not yet been achieved for solid tumors. Furthermore, tradi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c198ed4e1656db78e606d35925e469d
https://doi.org/10.1158/1538-7445.am2020-6593

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Preclinical Characterization of Prgn-3006 Ultracar-T™ for the Treatment of AML and MDS: Non-Viral, Multigenic Autologous CAR-T Cells Administered One Day after Gene Transfer

Autor: Jose Velez, Fernando Carvajal-Borda, Shah Rutul R, Helen Sabzevari, Xiaohong Ma, Lindsey Shepard, David A. Sallman, Tim Chan, Jacques Plummer

Publikováno v: Blood. 134:2660-2660

Relapsed/refractory (r/r) acute myeloid leukemia (AML) is an aggressive malignancy with poor prognosis and limited treatment options underscoring the need for new therapies. Traditional methods for generating CAR-T cells require extensive ex vivo exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcf2eb37f30ff3bd97c3377ac0c88090
https://doi.org/10.1182/blood-2019-130617

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