Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Fernando Cardozo-Pelaez"'
Autor:
Leslie S Itsara, Scott R Kennedy, Edward J Fox, Selina Yu, Joshua J Hewitt, Monica Sanchez-Contreras, Fernando Cardozo-Pelaez, Leo J Pallanck
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1003974 (2014)
The accumulation of somatic mitochondrial DNA (mtDNA) mutations is implicated in aging and common diseases of the elderly, including cancer and neurodegenerative disease. However, the mechanisms that influence the frequency of somatic mtDNA mutations
Externí odkaz:
https://doaj.org/article/81090a2719dd446a93d158b50a33ec35
Publikováno v:
Neurotoxicology. 57
Pb exposure is associated with cognitive deficits including Attention Deficit Hyperactivity Disorder (ADHD) in children and alters auditory temporal processing in humans and animals. Serotonin has been implicated in auditory temporal processing and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab5a584dddea0ae706f61932ca10898
https://pubmed.ncbi.nlm.nih.gov/27771255
https://pubmed.ncbi.nlm.nih.gov/27771255
Publikováno v:
Neurochemistry International. 61:721-730
Cumulative damage to cellular macromolecules via oxidative stress is a hallmark of aging and neurodegenerative disease. Whether such damage is a cause or a subsequent effect of neurodegeneration is still unknown. This paper describes the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5929bcd687162635cd9c5f4d33200207
https://doi.org/10.1016/j.neuint.2012.06.013
https://doi.org/10.1016/j.neuint.2012.06.013
Publikováno v:
Experimental Neurology. 235:508-512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e82b26b807c884a1bab8a7526e38598e
https://doi.org/10.1016/j.expneurol.2012.03.006
https://doi.org/10.1016/j.expneurol.2012.03.006
Publikováno v:
Free Radical Biology and Medicine. 46:1241-1249
article i nfo Alzheimer disease (AD) is a progressive neurodegenerative disorder whose clinical manifestations appear in old age. The sporadic nature of 90% of AD cases, the differential susceptibility to and course of the illness, as well as the lat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63003afa7cbb3514d0ccf198302216b3
https://doi.org/10.1016/j.freeradbiomed.2009.02.006
https://doi.org/10.1016/j.freeradbiomed.2009.02.006
Autor:
Celeste Bolin, Fernando Cardozo-Pelaez
Publikováno v:
Journal of Chromatography B. 856:121-130
Oxidation of the guanosine moiety in DNA has become a hallmark biomarker in assessing oxidative stress. The oxidation of guanosine in the nucleotide triphosphate pool has been overlooked due to the lack of a reliable methodology. This method describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe6424313f4f0e6efb9536e9db928f4
https://doi.org/10.1016/j.jchromb.2007.05.034
https://doi.org/10.1016/j.jchromb.2007.05.034
Publikováno v:
Journal of sports sciences. 33(16)
The purpose of this study was to determine the effects of repeated bouts of long-duration endurance exercise on both muscle and urinary levels of oxidative DNA damage in moderately trained individuals. Seven moderately trained male cyclists participa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8487a317d67d3a43384b426a104cea2c
https://pubmed.ncbi.nlm.nih.gov/25620316
https://pubmed.ncbi.nlm.nih.gov/25620316
Publikováno v:
Gene Expression. 12:315-323
Onset of Parkinson’s disease (PD) and Parkinson-like syndromes has been associated with exposure to diverse environmental stimuli. Epidemiological studies have demonstrated that exposure to elevated levels of manganese produces neuropathological ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6f62d38e89bcee8cd4efdba8814344
https://doi.org/10.3727/000000005783992007
https://doi.org/10.3727/000000005783992007
Publikováno v:
Scopus-Elsevier
The expression and activity of 8-oxoguanosine DNA-glycosylase (Ogg1), a key enzyme responsible for the clearance of the oxidized DNA base 8-hydroxy-2′-deoxyguanosine (oxo8dG), was determined in the cerebellum (CB) and the caudate and the putamen (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbaaa61f368d5f81f12deebcdec1a1f
https://doi.org/10.3727/000000003783992333
https://doi.org/10.3727/000000003783992333
Autor:
Scott R. Kennedy, Monica Sanchez-Contreras, Joshua J. Hewitt, Fernando Cardozo-Pelaez, Edward J. Fox, Leslie S. Itsara, Selina Yu, Leo J. Pallanck
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 10, Iss 2, p e1003974 (2014)
PLoS Genetics, Vol 10, Iss 2, p e1003974 (2014)
The accumulation of somatic mitochondrial DNA (mtDNA) mutations is implicated in aging and common diseases of the elderly, including cancer and neurodegenerative disease. However, the mechanisms that influence the frequency of somatic mtDNA mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec38b52680ff70755fad22e3648c3591
http://europepmc.org/articles/PMC3916223
http://europepmc.org/articles/PMC3916223