Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Fernando Arias-Mendoza"'
Autor:
Kavindra Nath, Pradeep K. Gupta, Johnvesly Basappa, Shengchun Wang, Neil Sen, Cosimo Lobello, Jyoti S. Tomar, Alexander A. Shestov, Stepan Orlovskiy, Fernando Arias-Mendoza, Hilka Rauert-Wunderlich, David S. Nelson, Jerry D. Glickson, Mariusz A. Wasik
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Inhibition of kinases is the ever-expanding therapeutic approach to various types of cancer. Typically, assessment of the treatment response is accomplished by standard, volumetric imaging procedures, performed weeks to months aft
Externí odkaz:
https://doaj.org/article/0e7806c50fd74e3da89b30454ab92a58
Autor:
Pradeep Kumar Gupta, Stepan Orlovskiy, Fernando Arias-Mendoza, David S. Nelson, Kavindra Nath
Publikováno v:
Cells, Vol 13, Iss 14, p 1220 (2024)
The MAPK signaling pathway with BRAF mutations has been shown to drive the pathogenesis of 40–60% of melanomas. Inhibitors of this pathway’s BRAF and MEK components are currently used to treat these malignancies. However, responses to these treat
Externí odkaz:
https://doaj.org/article/a659ad883c1c4462bc1a2a5317e66921
Autor:
Stepan Orlovskiy, Pradeep Kumar Gupta, Jeffrey Roman, Fernando Arias-Mendoza, David S. Nelson, Cameron J. Koch, Vivek Narayan, Mary E. Putt, Kavindra Nath
Publikováno v:
Cancers, Vol 16, Iss 7, p 1384 (2024)
Prostate cancer is a multi-focal disease that can be treated using surgery, radiation, androgen deprivation, and chemotherapy, depending on its presentation. Standard dose-escalated radiation therapy (RT) in the range of 70–80 Gray (GY) is a standa
Externí odkaz:
https://doaj.org/article/6ec6c4c54f124352ab893d2011e890f3
Autor:
Pradeep Kumar Gupta, Stepan Orlovskiy, Fernando Arias-Mendoza, David S. Nelson, Aria Osborne, Stephen Pickup, Jerry D. Glickson, Kavindra Nath
Publikováno v:
Cancers, Vol 16, Iss 2, p 365 (2024)
Dabrafenib therapy for metastatic melanoma focuses on blocking growth-promoting signals produced by a hyperactive BRAF protein. We report the metabolic differences of four human melanoma cell lines with diverse responses to dabrafenib therapy (30 mg/
Externí odkaz:
https://doaj.org/article/bd053a736bc146e48e781f2d1ddfa4a8
Publikováno v:
Advances in experimental medicine and biology. 1395
As a phosphorus-containing molecule, nicotinamide adenine dinucleotide is visible by phosphorus magnetic resonance spectroscopy (
Publikováno v:
Advances in experimental medicine and biology. 1395
Importance of the redox status of nicotinamide adenine dinucleotide (NAD), including its oxidized (NAD
Publikováno v:
Magn Reson Imaging
(1)H magnetic resonance spectroscopy (MRS) with the multiple quantum coherence (MQC) technique allows for the detection of lactate, an end product of glycolysis, in the environment of lipids. The method can also be used to detect alanine, a byproduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb3b925aa7f756d9d292e326988562e
https://europepmc.org/articles/PMC10278950/
https://europepmc.org/articles/PMC10278950/
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031141898
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac733c5490ce9b0f08fd3eaacd041cac
https://doi.org/10.1007/978-3-031-14190-4_39
https://doi.org/10.1007/978-3-031-14190-4_39
Autor:
Seung-Cheol Lee, Hari Hariharan, Fernando Arias-Mendoza, Gabor Mizsei, Kavindra Nath, Sanjeev Chawla, Mark A Elliott, Ravinder Reddy, Jerry D Glickson
Publikováno v:
Biomedical Physics & Engineering Express. 8:035004
Objective. The selective multiple quantum coherence (Sel-MQC) sequence is a magnetic resonance spectroscopy (MRS) technique used to detect lactate and suppress co-resonant lipid signals in vivo. The coherence pathways of J-coupled lipids upon the seq
Autor:
Zhezhen Jin, Pamela U. Freda, Wei Shen, Serge Cremers, Adi Cohen, Hamed Mojahed, Elizabeth Shane, Fernando Arias-Mendoza, Adriana P. Kuker
Publikováno v:
Journal of the Endocrine Society
Adipose tissue (AT) mass, especially visceral (VAT), is reduced in active acromegaly and rises with treatment. Although the effect of acromegaly and its therapy on marrow AT(MAT) is unknown, data in other populations and in vitro, suggest a reciproca