Zobrazeno 1 - 10
of 1 259
pro vyhledávání: '"Fernando Albericio"'
Autor:
Omar F. Luna, Yomkippur V. Perez, Daniele P. Ferrari, Sana S. Sayedipour, Miriam Royo, Gerardo A. Acosta, Luis J. Cruz, Frauke Alves, Erik Agner, Magne O. Sydnes, Fernando Albericio
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 34544-34554 (2024)
Externí odkaz:
https://doaj.org/article/a9c3cf5149c04adc9dd0a7f27bf09808
Autor:
Hlobisile Nzama, Srinivas Rao Manne, Oleg Marder, Gyorgy Orosz, Beatriz G. de la Torre, Fernando Albericio
Publikováno v:
Green Chemistry Letters and Reviews, Vol 17, Iss 1 (2024)
Although N-ethyl-N’-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC.HCl) is a common reagent in peptide synthesis, it presents two drawbacks. First of all, it is in a tautomerism equilibrium with cyclic form that it is not productive. Secon
Externí odkaz:
https://doaj.org/article/adbd819b867e4545bd2fff0c77dbc9ea
Publikováno v:
Green Chemistry Letters and Reviews, Vol 17, Iss 1 (2024)
ABSTRACTTriethyl phosphate (TEP) is a new member of the Green Solid-Phase Peptide Synthesis (GSPPS) toolbox. TEP shows almost no toxicity and no carcinogenic or mutagenic properties. It degrades, giving the rather innocuous phosphoric acid and ethano
Externí odkaz:
https://doaj.org/article/5c02bbf184374f19944c77f13cec1911
Autor:
Ndumiso Mthethwa, K. P. Nandhini, Ashish Kumar, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio
Publikováno v:
Green Chemistry Letters and Reviews, Vol 17, Iss 1 (2024)
ABSTRACTSolid-phase peptide synthesis (SPPS) is the method of choice for the synthesis of peptides for research and production purposes. Despite having several positive features, it remains a challenge to reduce the amount of solvent waste generated
Externí odkaz:
https://doaj.org/article/0889af9756644aeda8f9f661ccbc1e20
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1992 (2024)
An increase in total drug (small molecules and biologics) approvals by the Food and Drug Administration (FDA) was seen in 2023 compared with the previous year. Cancer remained the disease most targeted by monoclonal antibodies (mAbs), followed by aut
Externí odkaz:
https://doaj.org/article/902e380c36ce4c5db7917634e9859827
Autor:
Fanny Guzmán, Mónica Aróstica, Tanya Román, Dina Beltrán, Adriana Gauna, Fernando Albericio, Constanza Cárdenas
Publikováno v:
Electronic Journal of Biotechnology, Vol 64, Iss , Pp 27-33 (2023)
Background: Solid-Phase Peptide Synthesis (SPPS) is a mature technique widely used in research and in production. There are different approaches that fulfill the diverse requirements, regarding the number, quantity and quality of peptides. We have im
Externí odkaz:
https://doaj.org/article/9d3574fc92b84afab19ecde260d2eaf5
Publikováno v:
Molecules, Vol 29, Iss 7, p 1429 (2024)
Solid-phase peptide synthesis (SPPS) is the preferred strategy for synthesizing most peptides for research purposes and on a multi-kilogram scale. One key to the success of SPPS is the continual evolution and improvement of the original method propos
Externí odkaz:
https://doaj.org/article/a2dba798e30b466fb2a67f9f6f1344eb
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract Antimicrobial peptides (AMPs) are essential elements of thehost defense system. Characterized by heterogenous structures and broad‐spectrumaction, they are promising candidates for combating multidrug resistance. Thecombined use of AMPs wi
Externí odkaz:
https://doaj.org/article/15b6379146354c88bbeeca7d004f3ba2
Autor:
Roberto Rojas, Mónica Aróstica, Patricio Carvajal-Rondanelli, Fernando Albericio, Fanny Guzmán, Constanza Cárdenas
Publikováno v:
Electronic Journal of Biotechnology, Vol 59, Iss , Pp 62-73 (2022)
Background: Antifreezing activity is a phenomenon of great significance in food industry that affects the quality of frozen foods. As a solution, ice-binding proteins, more specifically antifreeze proteins, have been used to mitigate recrystallizatio
Externí odkaz:
https://doaj.org/article/46c6b932f9ef422d976e911bae555fc3
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 243 (2024)
A total of nine TIDES (pepTIDES and oligonucleoTIDES) were approved by the FDA during 2023. The four approved oligonucleotides are indicated for various types of disorders, including amyotrophic lateral sclerosis, geographic atrophy, primary hyperoxa
Externí odkaz:
https://doaj.org/article/4dae35486161477388f8e34c1bc7a62d