Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fernando A. Alvarez‐Núñez"'
Publikováno v:
International Journal of Pharmaceutics. 185:45-49
The main objective of this investigation is to develop a phenytoin (DPH) intravenous formulation that does not precipitate upon dilution. The effect of the buffer capacity at pH 12 of several DPH formulations on the extent and lag-time of DPH precipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba9d398e61658b5d169813fe3f1e1b1
https://doi.org/10.1016/s0378-5173(99)00129-5
https://doi.org/10.1016/s0378-5173(99)00129-5
Publikováno v:
Journal of pharmaceutical sciences. 103(7)
The purpose of this study is to investigate if Johanson's rolling theory can correctly predict the maximum roll surface pressure during the roll compaction. Three model pharmaceutical formulations were roller compacted using the Gerteis Mini Pactor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67be866eb17c30e11d297df64aaeafbc
https://pubmed.ncbi.nlm.nih.gov/24840775
https://pubmed.ncbi.nlm.nih.gov/24840775
Publikováno v:
Journal of Pharmaceutical Sciences. 88:1041-1043
A novel method for quantifying hemolysis is described. This method uses a spin filter to separate the free hemoglobin from the red blood cells suspended in the test solution. This procedure enables the use of a closed loop system that continuously me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ffd986c2f8c51f4832e90e41d04ce6
https://doi.org/10.1021/js980484l
https://doi.org/10.1021/js980484l
Publikováno v:
Journal of Pharmaceutical Sciences. 88:535-537
A spectrophotometric technique was used to determine the acidity constants of 4-dedimethylamino sancycline (Col-3), a new antitumor drug. The apparent pKa values of Col-3 in 0.5% methanol aqueous media at approximately 25 degrees C with a constant io
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642944d47cd63914b9f734e3c4cc22d9
https://doi.org/10.1021/js980398l
https://doi.org/10.1021/js980398l
Publikováno v:
Journal of Pharmaceutical Sciences. 86:1187-1189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0298d34c593446b989f634155183e3
https://doi.org/10.1021/js970050a
https://doi.org/10.1021/js970050a
Publikováno v:
International journal of pharmaceutics. 181(1)
The kinetics of degradation of the new anti-tumor drug, 4-dedimethylamino sancycline (col-3) in aqueous solution at 25 o C were investigated by high-pressure liquid chromatography (HPLC) over the pH-range of 2–10. The influences of pH, buffer conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1f97920647680cf940c0711b3c398b
https://pubmed.ncbi.nlm.nih.gov/10370200
https://pubmed.ncbi.nlm.nih.gov/10370200
Publikováno v:
Journal of pharmaceutical sciences. 86(11)
The dynamic in vitro method developed by the authors and other available in vitro methods were used to determine the degree of hemolysis induced by several cosolvent vehicles that have previously been evaluated in vivo. The in vitro data generated fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ca07655d920ef3a1fac6cec56dcbc3
https://pubmed.ncbi.nlm.nih.gov/9383728
https://pubmed.ncbi.nlm.nih.gov/9383728