Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Fernando, Villalta"'
Autor:
Amita R. Banga, Konjeti R. Sekhar, Kayla J. Rayford, Ashutosh Arun, Peace Odiase, Amar P. Garg, Maria F. Lima, Pius N. Nde, Fernando Villalta, Girish Rachakonda
Publikováno v:
Microbiology Research, Vol 13, Iss 4, Pp 721-739 (2022)
Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, has infected 6 million people, putting 70 million people at risk worldwide. Presently, very limited drugs are available, and these have severe side effects. Hence, there is an urgen
Externí odkaz:
https://doaj.org/article/c7ef648b155a4e2099e56b079b3b2c22
Autor:
Bobby Jones, Muthukumar Balasubramaniam, Joseph J. Lebowitz, Anne Taylor, Fernando Villalta, Habibeh Khoshbouei, Carrie Grueter, Brad Grueter, Chandravanu Dash, Jui Pandhare
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Methamphetamine (METH) is a highly addictive psychostimulant that causes long-lasting effects in the brain and increases the risk of developing neurodegenerative diseases. The cellular and molecular effects of METH in the brain are functiona
Externí odkaz:
https://doaj.org/article/c14ac558b3974efd995809baf00a9f90
Autor:
Ashutosh Arun, Kayla J. Rayford, Ayorinde Cooley, Tanu Rana, Girish Rachakonda, Fernando Villalta, Siddharth Pratap, Maria F. Lima, Nader Sheibani, Pius N. Nde
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 1 (2022)
The protozoan parasite, Trypanosoma cruzi, causes severe morbidity and mortality in afflicted individuals. Approximately 30% of T. cruzi infected individuals present with cardiac pathology. The invasive forms of the parasite are carried in the vascul
Externí odkaz:
https://doaj.org/article/4ab06a4d3efe4b5cb0eeaa8e98b6b6fd
Publikováno v:
Microorganisms, Vol 9, Iss 9, p 1965 (2021)
Acute and chronic upper respiratory illnesses such as asthma, and allergic rhinitis (AR) have been linked to the presence of microorganisms in the nose. Microorganisms can exist in symbiotic or commensal relationships with the human body. However, in
Externí odkaz:
https://doaj.org/article/0d6ddbb1e6c34339b9db322ebc2200a2
Autor:
Xiangxu Jia, Qiujia Shao, Ahsen R. Chaudhry, Ballington L. Kinlock, Michael G. Izban, Hong-Ying Zhang, Fernando Villalta, James E. K. Hildreth, Bindong Liu
Publikováno v:
Pathogens, Vol 10, Iss 9, p 1192 (2021)
Medroxyprogesterone acetate (MPA) is one of the most widely used contraceptives in the world. Epidemiologic studies have uncovered a possible link between the use of MPA and an increased risk of HIV-1 transmission. However, the understanding of the m
Externí odkaz:
https://doaj.org/article/7749a4a22dd742c5b465f5c348a07b77
Autor:
Kayla J. Rayford, Ayorinde Cooley, Jelonia T. Rumph, Ashutosh Arun, Girish Rachakonda, Fernando Villalta, Maria F. Lima, Siddharth Pratap, Smita Misra, Pius N. Nde
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2373 (2021)
Advances in understanding disease pathogenesis correlates to modifications in gene expression within different tissues and organ systems. In depth knowledge about the dysregulation of gene expression profiles is fundamental to fully uncover mechanism
Externí odkaz:
https://doaj.org/article/25c397826b29483cad567009179d2f00
Autor:
Kayla J. Rayford, Ayorinde Cooley, Ashutosh Arun, Girish Rachakonda, Yulia Kleschenko, Fernando Villalta, Siddharth Pratap, Maria F. Lima, Pius N. Nde
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9439 (2020)
Trypanosoma cruzi dysregulates the gene expression profile of primary human cardiomyocytes (PHCM) during the early phase of infection through a mechanism which remains to be elucidated. The role that small non-coding RNAs (sncRNA) including PIWI-inte
Externí odkaz:
https://doaj.org/article/ec66d19599fe4b74baecb57db23bc584
Autor:
Qiana L. Matthews, Anitra L. Farrow, Girish Rachakonda, Linlin Gu, Pius Nde, Alexandre Krendelchtchikov, Siddarth Pratap, Shruti S. Sakhare, Steffanie Sabbaj, Maria F. Lima, Fernando Villalta
Publikováno v:
Pathogens and Immunity, Vol 1, Iss 2, Pp 214-233 (2016)
Background: Previously we reported that a hexon-modified adenovirus (Ad) vector containing the invasive neutralizing epitope of Trypanosoma cruzi (T. cruzi) trypomastigote gp83 (Ad5-gp83) provided immunoprotection against T. cruzi infection. The purp
Externí odkaz:
https://doaj.org/article/bd0d3cb000fb4d4c80ce6a4ba23b0968
Autor:
Tatiana Y, Hargrove, Zdzislaw, Wawrzak, Girish, Rachakonda, W David, Nes, Fernando, Villalta, F Peter, Guengerich, Galina I, Lepesheva
Publikováno v:
J Med Chem
Naegleria fowleri is the protozoan pathogen that causes primary amoebic meningoencephalitis (PAM), with the death rate exceeding 97%. The amoeba makes sterols and can be targeted by sterol biosynthesis inhibitors. Here, we characterized N. fowleri st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c8ec3bc279ee3a431fadf9f6d3ff415
https://pubmed.ncbi.nlm.nih.gov/34842434
https://pubmed.ncbi.nlm.nih.gov/34842434
Autor:
Ashutosh Arun, Kayla J. Rayford, Ayorinde Cooley, Girish Rachakonda, Fernando Villalta, Siddharth Pratap, Maria F. Lima, Nader Sheibani, Pius N. Nde
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 4912 (2020)
The protozoan parasite Trypanosoma cruzi is the causative agent of Chagas disease. This neglected tropical disease causes severe morbidity and mortality in endemic regions. About 30% of T. cruzi infected individuals will present with cardiac complica
Externí odkaz:
https://doaj.org/article/695033404085467f9ed788142d3b3710