Výsledky vyhledávání - "Fernando, López Ortiz"

Akademický článek

Heteroleptic (S^C)-cyclometallated gold(III) complexes as novel antiviral agents

Autor: María Balsera-Manzanero, Raquel G. Soengas, Marta Carretero-Ledesma, Carlos Ratia, M. José Iglesias, Jerónimo Pachón, Fernando López-Ortiz, Elisa Cordero, Sara M. Soto, Javier Sánchez-Céspedes

Publikováno v: Heliyon, Vol 10, Iss 6, Pp e27601- (2024)

Despite the increasingly widespread clinical impact of adenovirus (HAdV) infections in healthy individuals and the associated high morbidity in immunosuppressed patients, particularly among the paediatric population, a specific treatment for this vir

Externí odkaz: https://doaj.org/article/601a9d107f2a4db9928fc98164eaeea2

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Akademický článek

Novel gold(III)-dithiocarbamate complex targeting bacterial thioredoxin reductase: antimicrobial activity, synergy, toxicity, and mechanistic insights

Autor: Carlos Ratia, Victoria Ballén, Yaiza Gabasa, Raquel G. Soengas, María Velasco-de Andrés, María José Iglesias, Qing Cheng, Francisco Lozano, Elias S. J. Arnér, Fernando López-Ortiz, Sara M. Soto

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

IntroductionAntimicrobial resistance is a pressing global concern that has led to the search for new antibacterial agents with novel targets or non-traditional approaches. Recently, organogold compounds have emerged as a promising class of antibacter

Externí odkaz: https://doaj.org/article/ab1334a2c52047a197d36e50253333a8

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Akademický článek

Synthesis of the cyanobacterial halometabolite Chlorosphaerolactylate B and demonstration of its antimicrobial effect in vitro and in vivo

Autor: Nikoline Jensen, Henrik Elvang Jensen, Bent Aalbaek, Sophie Amalie Blirup-Plum, Sara M. Soto, Virginio Cepas, Yuly López, Yaiza Gabasa, Ignacio Gutiérrez-del-Río, Claudio J. Villar, Felipe Lombó, María José Iglesias, Raquel Soengas, Fernando López Ortiz, Louise Kruse Jensen

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

Chlorosphaerolactylate B, a newly discovered antimicrobial halometabolite from the cyanobacterium Sphaerospermopsis sp. LEGE 00249 has been synthesized in three steps by using 12-bromododecanoic acid as starting material. A total of 0.5 g was produce

Externí odkaz: https://doaj.org/article/b16966e3ee034b1986c2264d1a65b441

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Akademický článek

A C∧S-Cyclometallated Gold(III) Complex as a Novel Antibacterial Candidate Against Drug-Resistant Bacteria

Autor: Carlos Ratia, Virginio Cepas, Raquel Soengas, Yolanda Navarro, María Velasco-de Andrés, María José Iglesias, Francisco Lozano, Fernando López-Ortiz, Sara M. Soto

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

The worldwide emergence and spread of infections caused by multidrug-resistant bacteria endangers the efficacy of current antibiotics in the clinical setting. The lack of new antibiotics in the pipeline points to the need of developing new strategies

Externí odkaz: https://doaj.org/article/69512af151854bfbac74475eaf108af1

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Akademický článek

Gold(III) Complexes Activity against Multidrug-Resistant Bacteria of Veterinary Significance

Autor: Carlos Ratia, Sara Sueiro, Raquel G. Soengas, María José Iglesias, Fernando López-Ortiz, Sara María Soto

Publikováno v: Antibiotics, Vol 11, Iss 12, p 1728 (2022)

The emergence and spread of multidrug-resistant bacteria are a global concern. The lack of new antibiotics in the pipeline points to the need for developing new strategies. In this sense, gold(III) complexes (G3Cs) could be a promising alternative du

Externí odkaz: https://doaj.org/article/fea6ea8eb9a44dc8942ee5b3b0811ff8

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Akademický článek

Microalgae and Cyanobacteria Strains as Producers of Lipids with Antibacterial and Antibiofilm Activity

Publikováno v: Marine Drugs, Vol 19, Iss 12, p 675 (2021)

Lipids are one of the primary metabolites of microalgae and cyanobacteria, which enrich their utility in the pharmaceutical, feed, cosmetic, and chemistry sectors. This work describes the isolation, structural elucidation, and the antibiotic and anti

Externí odkaz: https://doaj.org/article/37bd843ada6145ac90241f4700aa9eaf

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Synthesis of Pentacoordinated Spiro[4.4]phosphoranes by Reaction of Cyclic Phosphazenyl Anions with Epoxides: Study of their P-Remote Functionalization and Hydrolysis

Autor: María José Iglesias, Jesús García López, Fernando López Ortiz, Pablo M. Sansores Peraza, Yolanda Navarro

Publikováno v: Synthesis. 54:600-616

The synthesis of a new family of pentacoordinated spiro[4.4]phosphoranes stabilized by the ortho-benzamide bidentate ligand (oBA, -C6H4-2-C(O)NH-) through reaction of Cα,C ortho -dilithiated phosphazenes with oxiranes is reported. Mixtures of epimer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b40149010b8ea0ba98b284c0924e814
https://doi.org/10.1055/a-1644-2806

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Synthesis of Diethoxy Arylphosphoryl Functionalized, Fully Substituted 5-Triazenyl-1,2,3-triazoles via Chelation-Assisted Interrupted Domino Reaction of ortho-Azidophosphonates with Copper(I) Alkynes

Autor: Fernando López Ortiz, Yolanda Navarro, María José Iglesias, Ismael Heras-Jiménez

Publikováno v: Synthesis. 54:199-209

We describe the synthesis of 1,4-disubstituted 5-triazenyl-1,2,3-triazoles bearing diethoxy arylphosphoryl moieties via a domino reaction between ortho-azidophosphonates and premade copper(I) alkynides involving chelation-assisted [3+2] cycloaddition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9808dc21f822e25b927171e2a512380
https://doi.org/10.1055/a-1577-5999

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