Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa.

Autor: Janivara R; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Chen WC; Strengthening Oncology Services Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Cancer Registry, National Institute for Communicable Diseases a Division of the National Health Laboratory Service, Johannesburg, South Africa., Hazra U; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Baichoo S; University of Mauritius, Réduit, Mauritius., Agalliu I; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Kachambwa P; Centre for Proteomic and Genomic Research, Cape Town, South Africa.; Mediclinic Precise Southern Africa, Cape Town, South Africa., Simonti CN; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Brown LM; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Tambe SP; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Kim MS; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Harlemon M; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Jalloh M; Université Cheikh Anta Diop de Dakar, Dakar, Senegal.; Université Iba Der Thiam de Thiès, Thiès, Senegal., Muzondiwa D; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Naidoo D; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Ajayi OO; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Snyper NY; 37 Military Hospital, Accra, Ghana., Niang L; Université Cheikh Anta Diop de Dakar, Dakar, Senegal., Diop H; Université Cheikh Anta Diop de Dakar, Dakar, Senegal., Ndoye M; Université Cheikh Anta Diop de Dakar, Dakar, Senegal., Mensah JE; Korle-Bu Teaching Hospital and University of Ghana Medical School, Accra, Ghana., Abrahams AOD; Korle-Bu Teaching Hospital and University of Ghana Medical School, Accra, Ghana., Biritwum R; Korle-Bu Teaching Hospital and University of Ghana Medical School, Accra, Ghana., Adjei AA; Department of Pathology, University of Ghana Medical School, Accra, Ghana., Adebiyi AO; College of Medicine, University of Ibadan, Ibadan, Nigeria., Shittu O; College of Medicine, University of Ibadan, Ibadan, Nigeria., Ogunbiyi O; College of Medicine, University of Ibadan, Ibadan, Nigeria., Adebayo S; College of Medicine, University of Ibadan, Ibadan, Nigeria., Nwegbu MM; College of Health Sciences, University of Abuja, University of Abuja Teaching Hospital and Cancer Science Centre, Abuja, Nigeria., Ajibola HO; College of Health Sciences, University of Abuja, University of Abuja Teaching Hospital and Cancer Science Centre, Abuja, Nigeria., Oluwole OP; College of Health Sciences, University of Abuja, University of Abuja Teaching Hospital and Cancer Science Centre, Abuja, Nigeria., Jamda MA; College of Health Sciences, University of Abuja, University of Abuja Teaching Hospital and Cancer Science Centre, Abuja, Nigeria., Pentz A; Strengthening Oncology Services Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Haiman CA; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Spies PV; Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., van der Merwe A; Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Cook MB; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA., Watya S; Uro Care, Kampala, Uganda., Lubwama A; Uro Care, Kampala, Uganda., Muchengeti M; National Cancer Registry, National Institute for Communicable Diseases a Division of the National Health Laboratory Service, Johannesburg, South Africa., Doherty S; Division of Urology, Department of Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Smyth N; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Lounsbury D; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Fortier B; Dana-Farber Cancer Institute, Boston, MA, USA., Rohan TE; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Jacobson JS; Herbert Irving Comprehensive Cancer Center, Columbia University, New York City, NY, USA., Neugut AI; Herbert Irving Comprehensive Cancer Center, Columbia University, New York City, NY, USA., Hsing AW; Stanford Cancer Institute, Stanford University, Stanford, CA, USA., Gusev A; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Aisuodionoe-Shadrach OI; College of Health Sciences, University of Abuja, University of Abuja Teaching Hospital and Cancer Science Centre, Abuja, Nigeria., Joffe M; Strengthening Oncology Services Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Adusei B; 37 Military Hospital, Accra, Ghana., Gueye SM; Université Cheikh Anta Diop de Dakar, Dakar, Senegal., Fernandez PW; Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., McBride J; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Andrews C; Dana-Farber Cancer Institute, Boston, MA, USA., Petersen LN; Centre for Proteomic and Genomic Research, Cape Town, South Africa.; Mediclinic Precise Southern Africa, Cape Town, South Africa., Lachance J; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA. joseph.lachance@biology.gatech.edu., Rebbeck TR; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA. timothy_rebbeck@dfci.harvard.edu.; Harvard T.H. Chan School of Public Health, Boston, MA, USA. timothy_rebbeck@dfci.harvard.edu.

Publikováno v: Nature genetics [Nat Genet] 2024 Oct; Vol. 56 (10), pp. 2093-2103. Date of Electronic Publication: 2024 Oct 02.

Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men.

Autor: Janivara R; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Hazra U; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Pfennig A; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Harlemon M; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.; Department of Biology, Morgan State University, Baltimore, Maryland, USA., Kim MS; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.; Department of Human Genetics University of Michigan, Ann Arbor, Michigan, USA., Eaaswarkhanth M; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA., Chen WC; Strengthening Oncology Services Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Cancer Registry, National Institute for Communicable Diseases a Division of the National Health Laboratory Service, Johannesburg, South Africa., Ogunbiyi A; College of Medicine, University of Ibadan, Ibadan, Nigeria., Kachambwa P; Centre for Proteomic and Genomic Research, Cape Town, South Africa.; Mediclinic Precise Southern Africa, Cape Town, South Africa., Petersen LN; Centre for Proteomic and Genomic Research, Cape Town, South Africa.; Mediclinic Precise Southern Africa, Cape Town, South Africa., Jalloh M; Université Cheikh Anta Diop de Dakar, Dakar, Senegal.; Université Iba Der Thiam de Thiès, Thiès, Senegal., Mensah JE; Korle-Bu Teaching Hospital and University of Ghana Medical School, Accra, Ghana., Adjei AA; Department of Pathology, University of Ghana Medical School, Accra, Ghana., Adusei B; 37 Military Hospital, Accra, Ghana., Joffe M; Strengthening Oncology Services Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Gueye SM; Université Cheikh Anta Diop de Dakar, Dakar, Senegal., Aisuodionoe-Shadrach OI; College of Health Sciences, University of Abuja, University of Abuja Teaching Hospital and Cancer Science Centre, Abuja, Nigeria., Fernandez PW; Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Rohan TE; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA., Andrews C; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Rebbeck TR; Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Adebiyi AO; College of Medicine, University of Ibadan, Ibadan, Nigeria., Agalliu I; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA., Lachance J; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 15. Date of Electronic Publication: 2024 Jan 15.

Decisional Conflict is Associated with Treatment Modality and not Disease Knowledge in South African Men with Prostate Cancer: Baseline Results from a Longitudinal Prospective Observational Study.

Autor: Irusen H; Department of Urology, Faculty of Medicine and Health Sciences, 26697Stellenbosch University, Cape Town, South Africa., Burger H; Division of Radiation Oncology, Department of Medical Imaging and Clinical Oncology, Tygerberg Academic Hospital and Faculty of Medicine and Health Sciences, 26697Stellenbosch University, Cape Town, South Africa., Fernandez PW; Department of Urology, Faculty of Medicine and Health Sciences, 26697Stellenbosch University, Cape Town, South Africa., Van der Merwe A; Department of Urology, Faculty of Medicine and Health Sciences, 26697Stellenbosch University, Cape Town, South Africa., Esterhuizen T; Biostatistics Unit, Faculty of Medicine and Health Sciences, 26697Stellenbosch University, Cape Town, South Africa., du Plessis DE; Department of Urology, Faculty of Medicine and Health Sciences, 26697Stellenbosch University, Cape Town, South Africa., Seedat S; Department of Psychiatry, Faculty of Medicine and Health Sciences, 26697Stellenbosch University, Cape Town, South Africa.

Publikováno v: Cancer control : journal of the Moffitt Cancer Center [Cancer Control] 2022 Jan-Dec; Vol. 29, pp. 10732748221082791.

A Custom Genotyping Array Reveals Population-Level Heterogeneity for the Genetic Risks of Prostate Cancer and Other Cancers in Africa.

Autor: Harlemon M; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia.; Clark Atlanta University, Atlanta, Georgia., Ajayi O; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Kachambwa P; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Kim MS; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia., Simonti CN; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia., Quiver MH; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia., Petersen DC; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Mittal A; Thermo Fisher Scientific, Santa Clara, California., Fernandez PW; Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Hsing AW; Stanford Cancer Institute, Stanford University, Stanford, California., Baichoo S; University of Mauritius, Réduit, Mauritius., Agalliu I; Albert Einstein College of Medicine, Bronx, New York., Jalloh M; Hôpital Général de Grand Yoff, Institut de Formation et de Recherche en Urologie et Santé Familiale, Dakar, Senegal., Gueye SM; Hôpital Général de Grand Yoff, Institut de Formation et de Recherche en Urologie et Santé Familiale, Dakar, Senegal., Snyper NYF; 37 Military Hospital, Accra, Ghana., Adusei B; 37 Military Hospital, Accra, Ghana., Mensah JE; Korle-Bu Teaching Hospital and University of Ghana, Accra, Ghana., Abrahams AOD; Korle-Bu Teaching Hospital and University of Ghana, Accra, Ghana., Adebiyi AO; College of Medicine, University of Ibadan, Ibadan, Nigeria., Orunmuyi AT; College of Medicine, University of Ibadan, Ibadan, Nigeria., Aisuodionoe-Shadrach OI; College of Health Sciences, University of Abuja and University of Abuja Teaching Hospital, Abuja, Nigeria., Nwegbu MM; College of Health Sciences, University of Abuja and University of Abuja Teaching Hospital, Abuja, Nigeria., Joffe M; Non-Communicable Diseases Research Division, Wits Health Consortium (PTY) Ltd, Johannesburg, South Africa.; MRC Developmental Pathways to Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa., Chen WC; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Cancer Registry, National Health Laboratory Service, Johannesburg, South Africa., Irusen H; Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Neugut AI; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York., Quintana Y; Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Seutloali M; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Fadipe MB; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Warren C; Thermo Fisher Scientific, Santa Clara, California., Woehrmann MH; Thermo Fisher Scientific, Santa Clara, California., Zhang P; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Maryland., Ongaco CM; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Maryland., Mawhinney M; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Maryland., McBride J; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Andrews CV; Dana-Farber Cancer Institute, Boston, Massachusetts., Adams M; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Maryland., Pugh E; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Maryland., Rebbeck TR; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Petersen LN; Centre for Proteomic and Genomic Research, Cape Town, South Africa., Lachance J; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia. joseph.lachance@biology.gatech.edu.

Publikováno v: Cancer research [Cancer Res] 2020 Jul 01; Vol. 80 (13), pp. 2956-2966. Date of Electronic Publication: 2020 May 11.