Silencing of microRNA-106b-5p prevents doxorubicin-mediated cardiotoxicity through modulation of the PR55α/YY1/sST2 signaling axis.

Autor: Lax A; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Soler F; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Fernandez Del Palacio MJ; Veterinary Hospital, University of Murcia 30100 Murcia, Spain., Pascual-Oliver S; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Ballester MR; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, 30120 Murcia, Spain., Fuster JJ; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain., Pascual-Figal D; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.; Cardiology Department, Hospital Virgen de la Arrixaca, IMIB-Arrixaca and University of Murcia, 30120 Murcia, Spain.; Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain., Asensio-Lopez MDC; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2023 May 03; Vol. 32, pp. 704-720. Date of Electronic Publication: 2023 May 03 (Print Publication: 2023).

Author Correction: Empagliflozin improves post-infarction cardiac remodeling through GTP enzyme cyclohydrolase 1 and irrespective of diabetes status.

Autor: Del Carmen Asensio Lopez M; Biomedical Research Institute Virgen de La Arrixaca (IMIB-Arrixaca), University of Murcia, Ctra. Madrid-Cartagena S/N, 30120, Murcia, Spain., Lax A; Biomedical Research Institute Virgen de La Arrixaca (IMIB-Arrixaca), University of Murcia, Ctra. Madrid-Cartagena S/N, 30120, Murcia, Spain. alax@um.es., Hernandez Vicente A; Cardiology Department, IMIB-Arrixaca, University of Murcia, Hospital Virgen de La Arrixaca, Murcia, Spain., Saura Guillen E; Endocrinology Department, Hospital Virgen de La Arrixaca, University of Murcia, Murcia, Spain., Hernandez-Martinez A; Endocrinology Department, Hospital Virgen de La Arrixaca, University of Murcia, Murcia, Spain., Fernandez Del Palacio MJ; Veterinary Medicine and Surgery Department, Veterinary Teaching Hospital, University of Murcia, Murcia, Spain., Bayes-Genis A; Heart Institute, Hospital Universitari German Trías I Puyol, CIBERCV, Badalona, Madrid, Spain., Pascual Figal DA; Cardiology Department, IMIB-Arrixaca, University of Murcia, Hospital Virgen de la ArrixacaLAIB room 2.52, Avda. Buenavista s/n, Murcia, 30120, Spain. dpascual@um.es.; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. dpascual@um.es.; CIBERCV, Madrid, Spain. dpascual@um.es.

Publikováno v: Scientific reports [Sci Rep] 2020 Oct 09; Vol. 10 (1), pp. 17266. Date of Electronic Publication: 2020 Oct 09.

Temporal changes in clinical and radiographic variables in dogs with preclinical myxomatous mitral valve disease: The EPIC study.

Autor: Boswood A; Department of Clinical Science and Services, The Royal Veterinary College, Hatfield, Hertfordshire, UK., Gordon SG; Department of Small Animal Clinical Sciences, Texas A&M University, College Station, Texas., Häggström J; Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden., Vanselow M; Biometrie and Statistik, Hannover, Germany., Wess G; Clinic of Small Animal Medicine, University of Munich, Munich, Germany., Stepien RL; School of Veterinary Medicine, Medical Sciences, University of Wisconsin Madison, Madison, Wisconsin., Oyama MA; Clinical Studies-Philadelphia, MJR-VHUP-Cardiology, University of Pennsylvania, Philadelphia, Pennsylvania., Keene BW; Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, North Carolina., Bonagura J; Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio., MacDonald KA; Animal Care Center, Rohnert Park, California., Patteson M; HeartVets @ Vale Referrals, The Animal Hospital, Stinchcombe, Dursley Glos, UK., Smith S; Sarah Smith Cardiology, Derby, UK., Fox PR; Department of Cardiology and Caspary Research Institute, Animal Medical Center, New York, New York., Sanderson K; Rocky Mountain Veterinary Cardiology, Boulder, Colorado., Woolley R; Cardio Respiratory Pet Referrals, Mordialloc, Melbourne, Victoria, Australia., Szatmári V; Faculty of Veterinary Medicine, Clinical Sciences of Companion Animals, Utrecht University, Utrecht, The Netherlands., Menaut P; Clinique Vétérinaire AQUIVET, Eysines, France., Church WM; Desert Veterinary Medical Specialists, Phoenix, Arizona., O'Sullivan ML; Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada., Jaudon JP; Clinique Veterinaire Des Etangs, Villars Les Dombes, France., Kresken JG; Clinic for Small Animals Kaiserberg, Duisburg, Germany., Rush J; School of Veterinary Medicine, Clinical Sciences, Tufts University Cummings, North Grafton, Massachusetts., Barrett KA; Cardiology, VCA West Los Angeles, Los Angeles, California., Rosenthal SL; CVCA Cardiac Care for Pets, Towson, Maryland., Saunders AB; Department of Small Animal Clinical Sciences, Texas A&M University, College Station, Texas., Ljungvall I; Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden., Deinert M; Fachtierarztpraxis Am Sandpfad, Wiesloch, Germany., Bomassi E; Centre Hospitalier Vétérinaire des Cordeliers, Cardiology, Meaux, Paris, France., Estrada AH; University of Florida College of Veterinary Medicine, Small Animal Clinical Sciences, Gainesville, Florida., Fernandez Del Palacio MJ; Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Spain., Moise NS; Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York., Abbott JA; Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia., Fujii Y; Azabu University, Surgery 1, Kanagawa, Japan., Spier A; Blue Pearl Veterinary Partners, Tampa, Florida., Luethy MW; Chicago Veterinary Emergency and Specialty Center, Chicago, Illinois., Santilli RA; Cardiology, Clinica Veterinaria Malpensa, Varese, Italy., Uechi M; Japan Animal Specialty Medical Institute Inc., JASMINE Veterinary Cardiovascular Medical Center, Yokohama, Japan., Tidholm A; Djursjukhuset Albano, Stockholm, Sweden., Schummer C; Boehringer Ingelheim, Animal Health, Ingelheim am Rhein, Germany., Watson P; Boehringer Ingelheim, Animal Health, Ingelheim am Rhein, Germany.

Publikováno v: Journal of veterinary internal medicine [J Vet Intern Med] 2020 May; Vol. 34 (3), pp. 1108-1118. Date of Electronic Publication: 2020 Mar 22.

Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKCα/Gal-3 pathway reduces left ventricular fibrosis following myocardial infarction.

Autor: Asensio-Lopez MDC; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, Murcia, Spain., Lax A; Biomedical Research Institute Virgen de la Arrixaca (IMIB-Arrixaca), University of Murcia, Murcia, Spain. Electronic address: alax@um.es., Fernandez Del Palacio MJ; Veterinary Teaching Hospital, Veterinary Medicine and Surgery Department, University of Murcia, Murcia, Spain., Sassi Y; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York., Hajjar RJ; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York., Pascual-Figal DA; Cardiology Department, Clinic and Universitary Hospital Virgen de la Arrixaca, Murcia, Spain; CIBER in Cardiovascular Diseases (CIBERCV), Madrid, Spain.

Publikováno v: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2018 Sep; Vol. 199, pp. 4-23. Date of Electronic Publication: 2018 Apr 23.

Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study.

Autor: Boswood A; department of Veterinary Clinical Sciences, The Royal Veterinary College, Hatfield, Hertfordshire, UK., Gordon SG; Small Animal Clinical Science, Texas A&M University, College Station, TX., Häggström J; Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden., Wess G; Clinic of Small Animal Medicine, University of Munich, Munich, Germany., Stepien RL; Medical Sciences, University of Wisconsin Madison School of Veterinary Medicine, Madison, WI., Oyama MA; Clinical Studies-Philadelphia, MJR-VHUP-Cardiology, University of Pennsylvania, Philadelphia, PA., Keene BW; Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC., Bonagura J; Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH., MacDonald KA; Animal Care Center, Rohnert Park, CA., Patteson M; HeartVets @ Vale Referrals, The Animal Hospital, Dursley, Gloucestershire, UK., Smith S; Sarah Smith Cardiology, Derby, UK., Fox PR; Animal Medical Center, New York, NY., Sanderson K; Rocky Mountain Veterinary Cardiology, Boulder, CO., Woolley R; Cardio Respiratory Pet Referrals Victoria, Mordialloc, Vic., Australia., Szatmári V; Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Menaut P; Internal Medicine and Cardiology, Clinique Vétérinaire Aquivet, Eysines, France., Church WM; Desert Veterinary Medical Specialists, Phoenix, AZ., O'Sullivan ML; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada., Jaudon JP; Clinique Veterinaire Des Etangs, Villars Les Dombes, France., Kresken JG; Clinic for Small Animals Kaiserberg, Duisburg, Germany., Rush J; Clinical Sciences, Tufts University Cummings School of Veterinary Medicine, North Grafton, MA., Barrett KA; Cardiology, VCA West Los Angeles, Los Angeles, CA., Rosenthal SL; CVCA Cardiac Care for Pets, Towson, MD., Saunders AB; Small Animal Clinical Science, Texas A&M University, College Station, TX., Ljungvall I; Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden., Deinert M; Tierklinik am Sandpfad, Wiesloch, Germany., Bomassi E; Cardiology, Centre Hospitalier Vétérinaire des Cordeliers, Meaux, France., Estrada AH; Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, FL., Fernandez Del Palacio MJ; Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Spain., Moise NS; Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY., Abbott JA; Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA., Fujii Y; Surgery 1, Azabu University, Sagamihara, Kanagawa, Japan., Spier A; Blue Pearl Veterinary Partners, Tampa, FL., Luethy MW; Chicago Veterinary Emergency and Specialty Center, Chicago, IL., Santilli RA; Cardiology, Clinica Veterinaria Malpensa, Gallarate, Varese, Italy., Uechi M; Japan Animal Specialty Medical Institute Inc., JASMINE Veterinary Cardiovascular Medical Center, Yokohama, Japan., Tidholm A; Djursjukhuset Albano, Danderyd, Sweden., Schummer C; Animal Health, Boehringer Ingelheim, Ingelheim am Rhein, Germany., Watson P; Animal Health, Boehringer Ingelheim, Ingelheim am Rhein, Germany.

Publikováno v: Journal of veterinary internal medicine [J Vet Intern Med] 2018 Jan; Vol. 32 (1), pp. 72-85. Date of Electronic Publication: 2017 Dec 06.