Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fernanda V S Castanheira"'
Autor:
Danielle P A Mascarenhas, Daiane M Cerqueira, Marcelo S F Pereira, Fernanda V S Castanheira, Talita D Fernandes, Graziele Z Manin, Larissa D Cunha, Dario S Zamboni
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006502 (2017)
Legionella pneumophila is a Gram-negative, flagellated bacterium that survives in phagocytes and causes Legionnaires' disease. Upon infection of mammalian macrophages, cytosolic flagellin triggers the activation of Naip/NLRC4 inflammasome, which culm
Externí odkaz:
https://doaj.org/article/fe345c0b68d746658de26232888e9bd3
Autor:
Fabiane Sônego, Fernanda V S Castanheira, Paula G Czaikoski, Alexandre Kanashiro, Fabricio O Souto, Rafael O França, Daniele C Nascimento, Andressa Freitas, Fernando Spiller, Larissa D Cunha, Dario S Zamboni, José C Alves-Filho, Fernando Q Cunha
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103734 (2014)
Pathogen recognition and triggering of the inflammatory response following infection in mammals depend mainly on Toll-like and Nod-like receptors. Here, we evaluated the role of Nod1, Nod2 and MyD88-dependent signaling in the chemokine production and
Externí odkaz:
https://doaj.org/article/1c9d1f7145d646db84114adbe28eac30
Autor:
David F. Colón, Carlos W. Wanderley, Marcelo Franchin, Camila M. Silva, Carlos H. Hiroki, Fernanda V. S. Castanheira, Paula B. Donate, Alexandre H. Lopes, Leila C. Volpon, Silvia K. Kavaguti, Vanessa F. Borges, Cesar A. Speck-Hernandez, Fernando Ramalho, Ana P. Carlotti, Fabio Carmona, Jose C. Alves-Filho, Foo Y. Liew, Fernando Q. Cunha
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-13 (2019)
Abstract Background Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown. Methods Infant (2 weeks old) and adul
Externí odkaz:
https://doaj.org/article/33d631cf37c24ba2a665ac19751e0ba4
Autor:
Fernanda V. S. Castanheira, Paul Kubes
Publikováno v:
Immunological Reviews. 314:399-412
Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has resulted in more than 6 million deaths worldwide. COVID-19 is a respiratory disease characterized by pulmonary dysfunction leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc2308364c5c62d6ce2b3e0efbc7288
https://doi.org/10.1111/imr.13175
https://doi.org/10.1111/imr.13175
Autor:
Cesar L. Moreno, Fernanda V. S. Castanheira, Alberto Ospina Stella, Felicity Chung, Anupriya Aggarwal, Alexander J. Cole, Lipin Loo, Alexander Dupuy, Yvonne Kong, Lejla Hagimola, Jemma Fenwick, Paul Coleman, Michelle Willson, Maxwell Bui-Marinos, Daniel Hesselson, Jennifer Gamble, Freda Passam, Stuart Turville, Paul Kubes, G. Gregory Neely
COVID-19 causes a clinical spectrum of acute and chronic illness and host / virus interactions are not completely understood1,2. To identify host factors that can influence SARS-CoV-2 infection, we screened the human genome for genes that, when upreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4a19e378c3caf6ea3a3ae1473226e35
https://doi.org/10.1101/2023.02.13.528235
https://doi.org/10.1101/2023.02.13.528235
Autor:
David F. Colon, Carlos W. Wanderley, Walter M. Turato, Vanessa F. Borges, Marcelo Franchin, Fernanda V. S. Castanheira, Daniele Nascimento, Douglas Prado, Mikhael Haruo Fernandes de Lima, Leila C Volpon, Silvia K. Kavaguti, Fernando Ramalho, Ana P. Carlotti, Fabio Carmona, Bernardo S Franklin, Jose C. Alves-Filho, Fernando Q. Cunha
Sepsis survival in adults is commonly followed by immunosuppression and increased susceptibility to secondary infections. However, the long-term immune consequences of pediatric sepsis are unknown. Here, we compared the frequency of Tregs, the activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd58d397bc4e977b4ab60493a858a69
https://doi.org/10.1101/2022.01.15.476447
https://doi.org/10.1101/2022.01.15.476447
Autor:
Walter Miguel Turato, José C. Alves-Filho, Maria Auxiliadora-Martins, Fernando Q. Cunha, Anibal Basile-Filho, Braulio H.F. Lima, Fabricio O. Souto, Silvia Cellone Trevelin, Guilherme Cesar Martelossi Cebinelli, Fernanda V. S. Castanheira
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background Liver X receptors (LXRs) are nuclear receptors activated by oxidized lipids and were previously implicated in several metabolic development and inflammatory disorders. Although neutrophils express both LXR-α and LXR-β, the consequences o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf7be0511d2a99a8d0b5e363a6f52d8
https://doi.org/10.1093/infdis/jiz635
https://doi.org/10.1093/infdis/jiz635
Autor:
Mikhael Haruo Fernandes de Lima, Fernanda V. S. Castanheira, Valter Vinicius Silva Monteiro, Kalil Alves de Lima, Carlos Hiroji Hiroki, Daniele C. Nascimento, Fernando Q. Cunha, Thiago M. Cunha, José Carlos Farias Alves Filho, Guilherme Cesar Martelossi Cebinelli
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Inflammatory monocytes are recruited to both the infection site and vital organs during sepsis; however, the mechanisms that orchestrate thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dafb2b2ea378e7dd90d1442e6e3ef88
Autor:
Kalil Alves de Lima, Foo Y. Liew, José C. Alves-Filho, Jose Mauricio Mota, David-Fernando Colon, Paula Giselle Czaikoski, Fabiane Sônego, Fernando Q. Cunha, Fernanda V. S. Castanheira, Guilherme Cesar Martelossi Cebinelli, Alexandre Kanashiro, Thiago M. Cunha, Vanessa Araujo Borges
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Neutrophils and inflammatory monocytes control sepsis by migration to the site of infection via their chemokine receptors. CCR5 is a chemokine receptor that is not expressed on neutrophils and inflammatory monocytes under homeostatic conditions. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b01c402c9b2812024026ef177e960b
https://pubmed.ncbi.nlm.nih.gov/30724784
https://pubmed.ncbi.nlm.nih.gov/30724784
Autor:
Fernanda V. S. Castanheira, Fabio Carmona, Leila Costa Volpon, Cesar A. Speck-Hernandez, Camila Magalhães Silva, Fernando Q. Cunha, Foo Y. Liew, David F. Colón, Ana Paula de Carvalho Panzeri Carlotti, Carlos Hiroji Hiroki, Fernando Silva Ramalho, Alexandre H. Lopes, Carlos W. S. Wanderley, Vanessa F. Borges, Silvia K. Kavaguti, Marcelo Franchin, José C. Alves-Filho, Paula B. Donate
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Critical Care
Critical Care, Vol 23, Iss 1, Pp 1-13 (2019)
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
Universidade de São Paulo (USP)
instacron:USP
Critical Care
Critical Care, Vol 23, Iss 1, Pp 1-13 (2019)
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
Background Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown. Methods Infant (2 weeks old) and adult (6 week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34adf937351661d1026e027dad2715b