Optimized filopodia formation requires myosin tail domain cooperation

Autor: Ashley L. Arthur, Fernanda Pires Borrega, Carlos Kikuti, Livia D. Songster, Anne Houdusse, Akash Bhattacharya, Margaret A. Titus, Helena Sirkia

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (44), pp.22196-22204. ⟨10.1073/pnas.1901527116⟩

Filopodia are actin-filled protrusions employed by cells to interact with their environment. Filopodia formation in Amoebozoa and Metazoa requires the phylogenetically diverse MyTH4-FERM (MF) myosins DdMyo7 and Myo10, respectively. While Myo10 is kno

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https://hal.archives-ouvertes.fr/hal-02349330