Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Fernanda O. Novais"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cutaneous leishmaniasis exhibits a wide spectrum of clinical presentations from self-resolving infections to severe chronic disease. Anti-parasitic drugs are often ineffective in the most severe forms of the disease, and in some cases the magnitude o
Externí odkaz:
https://doaj.org/article/fc582bdbc9d7475cbc1c603aff8f0e21
Autor:
Laís A Sacramento, Camila Farias Amorim, Taís M Campos, Maíra Saldanha, Sérgio Arruda, Lucas P Carvalho, Daniel P Beiting, Edgar M Carvalho, Fernanda O Novais, Phillip Scott
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 8, p e0011552 (2023)
Cutaneous leishmaniasis exhibits a spectrum of clinical presentations dependent upon the parasites' persistence and host immunopathologic responses. Although cytolytic CD8 T cells cannot control the parasites, they significantly contribute to patholo
Externí odkaz:
https://doaj.org/article/e0207c6016624022a4aa50a9a9f1c4c6
Autor:
Stephen M Christensen, Laura A L Dillon, Lucas P Carvalho, Sara Passos, Fernanda O Novais, V Keith Hughitt, Daniel P Beiting, Edgar M Carvalho, Phillip Scott, Najib M El-Sayed, David M Mosser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005588 (2017)
[This corrects the article DOI: 10.1371/journal.pntd.0004992.].
Externí odkaz:
https://doaj.org/article/262fd8a16d9c4656b73e29de65da7b1f
Autor:
Stephen M Christensen, Laura A L Dillon, Lucas P Carvalho, Sara Passos, Fernanda O Novais, V Keith Hughitt, Daniel P Beiting, Edgar M Carvalho, Phillip Scott, Najib M El-Sayed, David M Mosser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004992 (2016)
Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patient
Externí odkaz:
https://doaj.org/article/bb0256dc2d5a46f3b743829cc856a81b
Autor:
Daniel P. Beiting, Phillip Scott, Fernanda O. Novais, Camila Farias Amorim, Ba T. Nguyen, Maurício T. Nascimento, Lucas P. Carvalho, Jamile Lago, Alexsandro S. Lago
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009321 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed to IFN-γ which triggers their ability to kill the intracellula
Autor:
Camila Farias Amorim, Victoria Lovins, Fernanda O. Novais, Jordan Harris, Lucas Carvalho, Edgar M. Carvalho, Daniel P. Beiting, Elizabeth Grice, Phillip A Scott
Publikováno v:
The Journal of Immunology. 208:170.13-170.13
Cutaneous leishmaniasis (CL) is a protozoal infection in which the immune response plays a major role in lesion development. The activation of local responses such as cytolysis by CD8+ T cells and release of IL-1β by myeloid cells is associated with
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Cutaneous leishmaniasis exhibits a wide spectrum of clinical presentations from self-resolving infections to severe chronic disease. Anti-parasitic drugs are often ineffective in the most severe forms of the disease, and in some cases the magnitude o
Autor:
Jamile Lago, Camila Farias Amorim, Lucas P. Carvalho, Ba T. Nguyen, Fernanda O. Novais, Phillip Scott, Maurício T. Nascimento, Alexsandro S. Lago, Daniel P. Beiting
Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed to IFN-γ which triggers their ability to kill the intracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bceb48c631343d3e296c480148cc2c55
https://doi.org/10.1101/2020.12.03.20240978
https://doi.org/10.1101/2020.12.03.20240978
Publikováno v:
The Journal of investigative dermatology. 141(3)
In cutaneous leishmaniasis, the immune response is not only protective but also mediates immunopathology. We previously found that cytolytic CD8 T cells promote inflammatory responses that are difficult to treat with conventional therapies that targe
Autor:
Daniel P. Beiting, Ba T. Nguyen, Edgar M. Carvalho, Fernanda O. Novais, Phillip Scott, Camila Farias Amorim, Lucas P. Carvalho, Ana M. Misic
Publikováno v:
Sci Transl Med
Patients infected with Leishmania braziliensis develop chronic lesions that often fail to respond to treatment with antiparasite drugs. To determine whether genes whose expression is highly variable in lesions between patients might influence disease