Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Fernanda O. Lemos"'
Publikováno v:
Cells, Vol 12, Iss 21, p 2527 (2023)
Pyruvate kinase M (PKM) 2 was described to interact with the inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) and suppress its activity. To further investigate the physiological importance of the PKM2:IP3R interaction, we developed and characterize
Externí odkaz:
https://doaj.org/article/27ab4587af484dc7a6da653475295f8a
Autor:
Dalton Dittz, Cinthia Figueiredo, Fernanda O. Lemos, Celso T. R. Viana, Silvia P. Andrade, Elaine M. Souza-Fagundes, Ricardo T. Fujiwara, Carlos E. Salas, Miriam T. P. Lopes
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 7027-7044 (2015)
The proteolytic enzymes from V. cundinamarcensis latex, (P1G10), display healing activity in animal models following various types of lesions. P1G10 or the purified isoforms act as mitogens on fibroblast and epithelial cells by stimulating angiogenes
Externí odkaz:
https://doaj.org/article/5f212d92a3a2401f8a171ba8f9b04021
Autor:
Fernanda O. Lemos, Dalton Dittz, Verlane G. Santos, Simone F. Pires, Hélida M. de Andrade, Carlos E. Salas, Miriam T. P. Lopes
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2846 (2018)
Previous studies showed that P1G10, a proteolytic fraction from Vasconcellea cundinamarcensis latex, reduced the tumor mass in animals bearing melanoma, increased in vitro DNA fragmentation and decreased cell adhesion. Here, we present some molecular
Externí odkaz:
https://doaj.org/article/5d12c86ae64d405f8ae5f1ebaf285847
Publikováno v:
Cell calcium. 104
Anti-apoptotic BCL-2 targets and inhibits IP
Autor:
Dabny Goulart Missiaggia, Marcone Loiola dos Santos, Mauro M. Teixeira, Ingredy Passos, Antônio Carlos Melo Lima Filho, Andressa França, Matheus de Castro Fonseca, Vivian Vasconcelos Costa, Antonio Marcio De Faria Andrade, Michael H. Nathanson, Gisele Olinto Libanio Rodrigues, M. Fatima Leite, Rodrigo M. Florentino, Fernanda O. Lemos, Felipe F. Dias, Paula Vieira Teixeira Vidigal, Cristiano Xavier Lima
Publikováno v:
Hepatology Communications, Vol 4, Iss 5, Pp 657-669 (2020)
Hepatology Communications
Hepatology Communications
Yellow fever (YF) is a viral hemorrhagic fever that typically involves the liver. Brazil recently experienced its largest recorded YF outbreak, and the disease was fatal in more than a third of affected individuals, mostly because of acute liver fail
Autor:
Antônio Carlos Melo Lima Filho, Marcone Loiola dos Santos, Carlos Alberto Xavier Gonçalves, Rodrigo M. Florentino, Paula Vieira Teixeira Vidigal, Vitor Lima Coelho, Andressa França, M. Fatima Leite, Cristiano Xavier Lima, Paulo Henrique Costa Diniz, Giselle Foureaux, Michael H. Nathanson, Fernanda O. Lemos
Publikováno v:
Oncology Letters
The expression of the inositol 1,4,5-trisphosphate receptor type 3 (ITRP3) in hepatocytes is a common event in the pathogenesis of hepatocellular carcinoma (HCC), regardless of the type of underlying liver disease. However, it is not known whether IT
Autor:
Andrew R, Lavik, Karen S, McColl, Fernanda O, Lemos, Martijn, Kerkhofs, Fei, Zhong, Michael, Harr, Daniela, Schlatzer, Kozo, Hamada, Katsuhiko, Mikoshiba, Francesco, Crea, Geert, Bultynck, Martin D, Bootman, Jan B, Parys, Clark W, Distelhorst
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1869(4)
Pyruvate kinase isoform M2 (PKM2) is a rate-limiting glycolytic enzyme that is widely expressed in embryonic tissues. The expression of PKM2 declines in some tissues following embryogenesis, while other pyruvate kinase isozymes are upregulated. Howev
Autor:
Meenakshisundaram Ananthanarayanam, Fernanda O. Lemos, Fulan Guan, Basile Njei, Emma A. Kruglov, Albert Mennone, André G. Oliveira, Maria de Fátima Leite, Rodrigo M. Florentino, Jianlei Gu, Marcone Loiola dos Santos, Andressa França, Joanna Gibson, Paula T Vidigal, Mateus T. Guerra, Roberta Cristelli Fonseca, Matheus de Castro Fonseca, Antônio Carlos Melo Lima Filho, Jianping Jiang, Hongyu Zhao, Michael H. Nathanson, Cristiano Xavier Lima, Yung-Chi Cheng
Publikováno v:
Gut. 68:1676-1687
Background & objectivesHepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide. Several types of chronic liver disease predispose to HCC, and several different signalling pathways have been implicated in its pathogenesis,
Inside cells, the endoplasmic reticulum (ER) forms the largest Ca2+ store. Ca2+ is actively pumped by the SERCA pumps in the ER, where intraluminal Ca2+-binding proteins enable the accumulation of large amount of Ca2+. IP3 receptors and the ryanodine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c958f3e153734b91680b68229eafe757
https://lirias.kuleuven.be/handle/123456789/673792
https://lirias.kuleuven.be/handle/123456789/673792
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1868(7)
Inside cells, the endoplasmic reticulum (ER) forms the largest Ca