Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Fernanda O Novais"'
Autor:
Laís A Sacramento, Camila Farias Amorim, Taís M Campos, Maíra Saldanha, Sérgio Arruda, Lucas P Carvalho, Daniel P Beiting, Edgar M Carvalho, Fernanda O Novais, Phillip Scott
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 8, p e0011552 (2023)
Cutaneous leishmaniasis exhibits a spectrum of clinical presentations dependent upon the parasites' persistence and host immunopathologic responses. Although cytolytic CD8 T cells cannot control the parasites, they significantly contribute to patholo
Externí odkaz:
https://doaj.org/article/e0207c6016624022a4aa50a9a9f1c4c6
Autor:
Camila Farias Amorim, Fernanda O Novais, Ba T Nguyen, Mauricio T Nascimento, Jamile Lago, Alexsandro S Lago, Lucas P Carvalho, Daniel P Beiting, Phillip Scott
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009321 (2021)
Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed to IFN-γ which triggers their ability to kill the intracellula
Externí odkaz:
https://doaj.org/article/831669485c7f4f5a89de9e4a4de5a7b9
Autor:
Stephen M Christensen, Laura A L Dillon, Lucas P Carvalho, Sara Passos, Fernanda O Novais, V Keith Hughitt, Daniel P Beiting, Edgar M Carvalho, Phillip Scott, Najib M El-Sayed, David M Mosser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005588 (2017)
[This corrects the article DOI: 10.1371/journal.pntd.0004992.].
Externí odkaz:
https://doaj.org/article/262fd8a16d9c4656b73e29de65da7b1f
Autor:
Fernanda O Novais, Augusto M Carvalho, Megan L Clark, Lucas P Carvalho, Daniel P Beiting, Igor E Brodsky, Edgar M Carvalho, Phillip Scott
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006196 (2017)
Deregulated CD8+ T cell cytotoxicity plays a central role in enhancing disease severity in several conditions. However, we have little understanding of the mechanisms by which immunopathology develops as a consequence of cytotoxicity. Using murine mo
Externí odkaz:
https://doaj.org/article/bf659d3cfad341d093c22b1295c01163
Autor:
Stephen M Christensen, Laura A L Dillon, Lucas P Carvalho, Sara Passos, Fernanda O Novais, V Keith Hughitt, Daniel P Beiting, Edgar M Carvalho, Phillip Scott, Najib M El-Sayed, David M Mosser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004992 (2016)
Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patient
Externí odkaz:
https://doaj.org/article/bb0256dc2d5a46f3b743829cc856a81b
Autor:
Taís M Campos, Sara T Passos, Fernanda O Novais, Daniel P Beiting, Rúbia S Costa, Adriano Queiroz, David Mosser, Phillip Scott, Edgar M Carvalho, Lucas P Carvalho
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 11, p e3282 (2014)
INTRODUCTION:Cutaneous leishmaniasis (CL) due to L.braziliensis infection is characterized by a strong inflammatory response with high levels of TNF and ulcer development. Less attention has been given to the role of mononuclear phagocytes to this pr
Externí odkaz:
https://doaj.org/article/e28e135f1ca6435c8f114cd50d44771f
Autor:
Fernanda O Novais, Lucas P Carvalho, Joel W Graff, Daniel P Beiting, Gordon Ruthel, David S Roos, Michael R Betts, Michael H Goldschmidt, Mary E Wilson, Camila I de Oliveira, Phillip Scott
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003504 (2013)
Disease progression in response to infection can be strongly influenced by both pathogen burden and infection-induced immunopathology. While current therapeutics focus on augmenting protective immune responses, identifying therapeutics that reduce in
Externí odkaz:
https://doaj.org/article/4f7dec74ed9c4d0dbd09cd51d83320cd
Autor:
Tatiana R de Moura, Fabiano Oliveira, Gabriele C Rodrigues, Marcia W Carneiro, Kiyoshi F Fukutani, Fernanda O Novais, José Carlos Miranda, Manoel Barral-Netto, Claudia Brodskyn, Aldina Barral, Camila I de Oliveira
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 6, p e712 (2010)
BACKGROUND: During blood feeding, sand flies inject Leishmania parasites in the presence of saliva. The types and functions of cells present at the first host-parasite contact are critical to the outcome on infection and sand fly saliva has been show
Externí odkaz:
https://doaj.org/article/a42109795f864b318766d93e74084be5
Autor:
Tatiana R de Moura, Fabiano Oliveira, Fernanda O Novais, José Carlos Miranda, Jorge Clarêncio, Ivonise Follador, Edgar M Carvalho, Jesus G Valenzuela, Manoel Barral-Netto, Aldina Barral, Cláudia Brodskyn, Camila I de Oliveira
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 1, Iss 2, p e84 (2007)
BACKGROUND: Sand fly saliva has an array of pharmacological and immunomodulatory components, and immunity to saliva protects against Leishmania infection. In the present study, we have studied the immune response against Lutzomyia intermedia saliva,
Externí odkaz:
https://doaj.org/article/85d0b9479e124914ae00363ffd4a0db7
Autor:
Daniel P. Beiting, Phillip Scott, Fernanda O. Novais, Camila Farias Amorim, Ba T. Nguyen, Maurício T. Nascimento, Lucas P. Carvalho, Jamile Lago, Alexsandro S. Lago
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009321 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Cutaneous leishmaniasis is a localized infection controlled by CD4+ T cells that produce IFN-γ within lesions. Phagocytic cells recruited to lesions, such as monocytes, are then exposed to IFN-γ which triggers their ability to kill the intracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c65311d0ba19bdf56a326ace1ecc8c9
https://doaj.org/article/831669485c7f4f5a89de9e4a4de5a7b9
https://doaj.org/article/831669485c7f4f5a89de9e4a4de5a7b9