A functionally augmented carbohydrate utilization locus from herbivore gut microbiota fueled by dietary β-glucans

Autor: Fernanda Mandelli, Marcele Pandeló Martins, Mariana Chinaglia, Evandro Antonio de Lima, Mariana Abrahão Bueno Morais, Tatiani Brenelli Lima, Lucélia Cabral, Renan Augusto Siqueira Pirolla, Felipe Jun Fuzita, Douglas Antônio Alvaredo Paixão, Maxuel de Oliveira Andrade, Lucia Daniela Wolf, Plinio Salmazo Vieira, Gabriela Felix Persinoti, Mario Tyago Murakami

Publikováno v: npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-13 (2024)

Abstract Gut microbiota members from the Bacteroidota phylum play a pivotal role in mammalian health and metabolism. They thrive in this diverse ecosystem due to their notable ability to cope with distinct recalcitrant dietary glycans via polysacchar

Externí odkaz: https://doaj.org/article/ef085d745e2d4d4a8bc56a8331f56b7a

Oxidative cleavage of polysaccharides by a termite-derived superoxide dismutase boosts the degradation of biomass by glycoside hydrolases

Autor: João Paulo L. Franco Cairo, Fernanda Mandelli, Robson Tramontina, David Cannella, Alessandro Paradisi, Luisa Ciano, Marcel R. Ferreira, Marcelo V. Liberato, Lívia B. Brenelli, Thiago A. Gonçalves, Gisele N. Rodrigues, Thabata M. Alvarez, Luciana S. Mofatto, Marcelo F. Carazzolle, José G. C. Pradella, Adriana F. Paes Leme, Ana M. Costa-Leonardo, Mário Oliveira-Neto, André Damasio, Gideon J. Davies, Claus Felby, Paul H. Walton, Fabio M. Squina

Publikováno v: Franco Cairo, J P L, Mandelli, F, Tramontina, R, Cannella, D, Paradisi, A, Ciano, L, Ferreira, M R, Liberato, M V, Brenelli, L B, Goncalves, T A, Rodrigues, G N, Alvarez, T M, Mofatto, L S, Carazzolle, M F, Pradella, J G C, Leme, A F P, Costa-Leonardo, A M, Oliveira-Neto, M, Damasio, A, Davies, G J, Felby, C, Walton, P H & Squina, F M 2022, ' Oxidative cleavage of polysaccharides by a termite-derived superoxide dismutase boosts the degradation of biomass by glycoside hydrolases ', Green Chemistry, vol. 24, no. 12, pp. 4845-4858 . https://doi.org/10.1039/d1gc04519a

Wood-feeding termites effectively degrade plant biomass through enzymatic degradation. Despite their high efficiencies, however, individual glycoside hydrolases isolated from termites and their symbionts exhibit anomalously low effectiveness in ligno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6bec8f2b4a169d8b8859cf96836695d
https://doi.org/10.1039/d1gc04519a

Development of an economically competitive Trichoderma-based platform for enzyme production: Bioprocess optimization, pilot plant scale-up, techno-economic analysis and life cycle assessment

Autor: Evandro Antonio de Lima, Fernanda Mandelli, Daniel Kolling, Jaqueline Matsusato Souza, Carlos Alberto de Oliveira Filho, Mateus Ribeiro da Silva, Isabelle Lobo de Mesquita Sampaio, Tassia Lopes Junqueira, Mateus Ferreira Chagas, Juliana Conceição Teodoro, Edvaldo Rodrigo de Morais, Mario Tyago Murakami

Publikováno v: Bioresource technology. 364

Despite decades of research and industrial applications of Trichoderma reesei, the development of industrially relevant strains for enzyme production including a low-cost and scalable bioprocess remains elusive. Herein, bioprocess optimization, pilot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c93455a84a55bca25082d66b9cd36e
https://pubmed.ncbi.nlm.nih.gov/36162784

Oxidative cleavage of polysaccharides by a termite-derived

Autor: João Paulo L, Franco Cairo, Fernanda, Mandelli, Robson, Tramontina, David, Cannella, Alessandro, Paradisi, Luisa, Ciano, Marcel R, Ferreira, Marcelo V, Liberato, Lívia B, Brenelli, Thiago A, Gonçalves, Gisele N, Rodrigues, Thabata M, Alvarez, Luciana S, Mofatto, Marcelo F, Carazzolle, José G C, Pradella, Adriana F, Paes Leme, Ana M, Costa-Leonardo, Mário, Oliveira-Neto, André, Damasio, Gideon J, Davies, Claus, Felby, Paul H, Walton, Fabio M, Squina

Publikováno v: Green chemistry : an international journal and green chemistry resource : GC. 24(12)

Wood-feeding termites effectively degrade plant biomass through enzymatic degradation. Despite their high efficiencies, however, individual glycoside hydrolases isolated from termites and their symbionts exhibit anomalously low effectiveness in ligno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a947b2a36cb90298fc84880de67afafb
https://pubmed.ncbi.nlm.nih.gov/35813357

Spatially remote motifs cooperatively affect substrate preference of a ruminal GH26-type endo-β-1,4-mannanase

Autor: Leane Oliveira, Mariana Abrahão Bueno de Morais, Mário T. Murakami, Gabriela Felix Persinoti, Evandro Antônio de Lima, Fernanda Mandelli

Publikováno v: J Biol Chem

β-Mannanases from the glycoside hydrolase 26 (GH26) family are retaining hydrolases that are active on complex heteromannans and whose genes are abundant in rumen metagenomes and metatranscriptomes. These enzymes can exhibit distinct modes of substr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb24330c20695a2d18cc645b4217dc7b
https://europepmc.org/articles/PMC7152760/