Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Fernanda M.F. Roleira"'
Autor:
Ana R. Gomes, Carla L. Varela, Ana S. Pires, Elisiário J. Tavares-da-Silva, Fernanda M.F. Roleira
Publikováno v:
Bioorganic Chemistry. 138:106600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fea6b006893a74f1f730653a435d561
https://doi.org/10.1016/j.bioorg.2023.106600
https://doi.org/10.1016/j.bioorg.2023.106600
Autor:
Ana M. T. D. P. V. Cabral, Elisiário J. T. Silva, Carla L. Varela, Saul C. Costa, Fernanda M.F. Roleira, I.R. Barbosa
Publikováno v:
Journal of Chemical Education. 97:2366-2369
Amides are usually prepared using amines and acyl halides, which often implies a two-step procedure. Alternatively, coupling reagents can be used in a single-step reaction with good yields, which seems to be suitable for organic chemistry laboratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cad9ed45d85cc1e107442d14ce036e88
https://doi.org/10.1021/acs.jchemed.8b00604
https://doi.org/10.1021/acs.jchemed.8b00604
Autor:
Fernanda M.F. Roleira, Saul C. Costa, Ana R. Gomes, Carla L. Varela, Cristina Amaral, Tiago V. Augusto, Georgina Correia-da-Silva, Isabella Romeo, Giosuè Costa, Stefano Alcaro, Natércia Teixeira, Elisiário J. Tavares-da-Silva
Publikováno v:
Bioorganic Chemistry. 131:106286
In this work, new steroidal aromatase inhibitors (AIs) were designed, synthesized, and tested. In one approach, C-ring substituted steroids namely those functionalized at C-11 position with an α or β hydroxyl group or with a carbonyl group as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60df53c25cd7903cfe3ad1f7f066661
https://doi.org/10.1016/j.bioorg.2022.106286
https://doi.org/10.1016/j.bioorg.2022.106286
In this chapter, a literature review on the health components of spices and medicinal herbs published from 2010 until 2019 is presented. Emphasis is given to the phenolic components present in the extracts of spices and medicinal herbs as well as to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893531ecc00d949466a679faea314c82
https://doi.org/10.1016/b978-0-12-822716-9.00002-0
https://doi.org/10.1016/b978-0-12-822716-9.00002-0
Autor:
Tinde van Andel, Ana M. Ares, José Bernal, José L. Bernal, Esra Capanoglu, Chien Hwa Chong, Bee Lin Chua, Gizem O. Cilak, Saul C. Costa, Adam Figiel, Yaiza Flores, María Carmen Garrigós, Ana R. Gomes, Alfonso Jiménez, Slaven Jurić, Bulent Kabak, Senem Kamiloglu, Chun Hong Khek, Danijela Bursać Kovačević, Marijan Marijan, Luna Maslov Bandić, Anca Mihaela Micu, Gamze N. Mujdeci, María J. Nozal, Tatiana Onisei, Tugba Ozdal, Branimir Pavlić, Carlos Javier Pelegrín, Predrag Putnik, Marina Ramos, Manuela Rascol, Fernanda M.F. Roleira, Antoni Szummy, Sarana Rose Sommano, Branislav Šojić, Anastasia Stefanaki, Tibet Tangpao, Elisiário J. Tavares-da-Silva, Nemanja Teslić, Merve Tomas, Gamze Toydemir, Carla L. Varela, Marko Vinceković, Marko Viskić, Kristina Vlahoviček-Kahlina, Aneta Wojdyło, Ma Chee Yuan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e606798117dc4906e4a374673161c5ce
https://doi.org/10.1016/b978-0-12-822716-9.00015-9
https://doi.org/10.1016/b978-0-12-822716-9.00015-9
Autor:
Carla L. Varela, Fernanda M.F. Roleira, Angel Concheiro, Carmen Alvarez-Lorenzo, Cátia Domingues, Ana Figueiras, Marília Dourado, Rui de Albuquerque Carvalho, Elisiário Tavares, Francisco Veiga, Ivana Jarak
Publikováno v:
The 1st International Electronic Conference on Pharmaceutics.
Polyethyleneimine (PEI) is a synthetic cationic polymer recognized as a non-viral gene carrier with high transfection efficiency [1]. However, cytotoxicity issues limit its use. Pluronic block-copolymers conjugated with PEI have demonstrated promisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98572ae6aefc0744ecd9be4f5b28d9cb
https://doi.org/10.3390/iecp2020-08795
https://doi.org/10.3390/iecp2020-08795
Autor:
Ana M. Abrantes, E. Tavares-Da-Silva, Carla L. Varela, Cristina Goncalves, Ana Salomé Pires, Maria Filomena Botelho, Fernanda M.F. Roleira, Inês A. Marques, Tiago B. Rodrigues, Paulo Matafome
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 212:105950
A new promising steroid derivative of Exemestane (Exe), the drug used for the treatment of estrogen-dependent breast cancer, was synthesized and evaluated against a set of human cancer cell lines. The new compound (Oxymestane-D1, Oxy) was tested comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6d9957e2d2337625344f0b42d47b80
https://doi.org/10.1016/j.jsbmb.2021.105950
https://doi.org/10.1016/j.jsbmb.2021.105950
Autor:
Carla L. Varela, Francisco Veiga, António J. Ribeiro, Claudia L. Oliveira, Fernanda M.F. Roleira, Isabel Silveira, Elisiário Tavares
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 150:326-333
The nano-bio interaction has been of increased focus in the past years but very limited results have been obtained for polymeric nanoparticles (NP). Not only is needed to broaden the results obtained with model NP towards other nano-materials used fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25219735b99f1855c4b1756d23b254bd
https://doi.org/10.1016/j.colsurfb.2016.10.046
https://doi.org/10.1016/j.colsurfb.2016.10.046
Autor:
Fernanda M.F. Roleira, Natércia Teixeira, Stefano Alcaro, Giosuè Costa, Elisiário J. Tavares da Silva, Cristina Amaral, Federica Moraca, Saul C. Costa, Carla L. Varela, Georgina Correia-da-Silva
Publikováno v:
Journal of medicinal chemistry. 62(7)
C-6α and C-7α androstanes were studied to disclose which position among them is more convenient to functionalize to reach superior aromatase inhibition. In the first series, the study of C-6 versus C-7 methyl derivatives led to the very active comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f6b73c7c8c06ef53cb077ecf35f418
https://pubmed.ncbi.nlm.nih.gov/30852901
https://pubmed.ncbi.nlm.nih.gov/30852901
Publikováno v:
European Journal of Medicinal Chemistry. 201:112327
Functional group modification is one of the main strategies used in drug discovery and development. Despite the controversy of being identified for many years as a biologically hazardous functional group, the introduction of an epoxide function in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f3a5860d1e331192c66e78bbafd62d
https://doi.org/10.1016/j.ejmech.2020.112327
https://doi.org/10.1016/j.ejmech.2020.112327