Výsledky vyhledávání - "Fernanda I. Simplicio"

In vitro inhibition of linoleic acid peroxidation by primary S-nitrosothiols

Autor: Gabriela F. P. de Souza, Marcelo Ganzarolli de Oliveira, Fernanda I. Simplicio, Amedea B. Seabra

Publikováno v: Journal of the Brazilian Chemical Society v.21 n.10 2010
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 21, Issue: 10, Pages: 1885-1895, Published: 2010

Nitric oxide (•NO) is an effective chain-breaking antioxidant in the inhibition of lipid peroxidation and circulates in vivo mainly as primary S-nitrosothiols (RSNOs). In this work, the in vitro peroxidation of linoleic acid-SDS comicelles (LA-SDS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae058ca959781f1ef286bc3825aa9f13
https://doi.org/10.1590/s0103-50532010001000013

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Hepatic gene expression profile associated with non-alcoholic steatohepatitis protection by S-nitroso-N-acetylcysteine in ob/ob mice

Autor: Sandra Valéria de Sá, Evandro Sobrosa Mello, Maria Lúcia Corrêa-Giannella, Flair José Carrilho, V. M. R. Lima, Claudia P. Oliveira, Marcelo Ganzarolli de Oliveira, Daniel Giannella-Neto, Fernanda I. Simplicio, Francisco R.M. Laurindo, Venâncio Avancini Ferreira Alves, José Tadeu Stefano

Publikováno v: Journal of Hepatology. 45:725-733

Background/Aims To understand the molecular mechanisms underlying non-alcoholic steatohepatitis (NASH) prevention by S -nitroso- N -acetylcysteine (SNAC), an NO donor that inhibits lipid peroxidation, we examined hepatic differentially expressed gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacad7168a6a91550242f4f8444de49f
https://doi.org/10.1016/j.jhep.2006.05.017

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Prevention and reversion of nonalcoholic steatohepatitis in OB/OB mice by S-nitroso-N-acetylcysteine treatment

Autor: V. M. R. Lima, Marcelo Ganzarolli de Oliveira, Claudia P. Oliveira, Flair José Carrilho, Venâncio Avancini Ferreira Alves, Fernanda I. Simplicio, Heraldo Possolo de Souza, Francisco Garcia Soriano, Evandro Sobroza de Mello, Francisco R.M. Laurindo

Publikováno v: Journal of the American College of Nutrition. 27(2)

Objective: To evaluate the role oral administration of S-nitroso-N-acetylcysteine (SNAC), a NO donor drug, in the prevention and reversion of NASH in two different animal models.Methods: NASH was induced in male ob/ob mice by methionine-choline defic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5177abc0d030fc9ae8f680a10084fc
https://pubmed.ncbi.nlm.nih.gov/18689562

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Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats

Autor: V. M. R. Lima, Claudia P. M. S. Oliveira, Fernanda I. Simplicio, Venancio Avancini Ferreira Alves, Marcelo Ganzarolli de Oliveira, Katia Kioko Yuahasi, Francisco R.M. Laurindo, Fabio Pinatel Lopasso, Flair José Carrilho, Dulcinéia Saes Parra Abdalla

Publikováno v: World Journal of Gastroenterology. 12:1905

To evaluate the potential of S-nitroso-N-acetylcysteine (SNAC) in inhibition of lipid peroxidation and the effect of oral SNAC administration in the prevention of nonalcoholic fatty liver disease (NAFLD) in an animal model.NAFLD was induced in Wistar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f06cec2641f2fbcffed3f76e4a0ef7
https://doi.org/10.3748/wjg.v12.i12.1905

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Akademický článek

Small aggregates of benzoporphyrin molecules observed in waterorganic solvent mixtures.

Autor: Fernanda I. Simplicio, Florângela Maionchi, Ourides Santin Filho, Noboru Hioka

Publikováno v: Journal of Physical Organic Chemistry; Apr2004, Vol. 17 Issue 4, p325-331, 7p

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