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pro vyhledávání: '"Fernanda Cinque"'
Autor:
Fernanda Cinque, Boccazzi C, Alfredo Brusco, A. van Leeuwen, Angelo O. Carbonara, G. G. de Lange, M DeMarchi, Silvia Saviozzi
Publikováno v:
European Journal of Immunogenetics. 25:349-355
The molecular bases of classical serological immunoglobulin allotypes are progressively uncovered through detailed characterization of the relevant genes. Here we describe two isoallotypic determinants of the G4 gene. In the first, Leu 309, as in G1
Autor:
Angelo O. Carbonara, Boccazzi C, Fernanda Cinque, M DeMarchi, Silvia Saviozzi, Alfredo Brusco
Publikováno v:
Human Genetics. 100:84-89
The structure of the human immunoglobulin heavy chain constant region (IGHC), on chromosome 14q32, comprises nine CH genes and two pseudogenes, all originating from multiple duplication events. Continuing evolution of the region is demonstrated by th