Zobrazeno 1 - 10 of 92 pro vyhledávání: '"Fernanda C. V. Portaro"'
1
Akademický článek
Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism
Autor: Priscila Hess Lopes, Mário T. Murakami, Fernanda C. V. Portaro, Kerly Fernanda Mesquita Pasqualoto, Carmen van den Berg, Denise V. Tambourgi
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 310-321 (2019)
Loxosceles spiders’ venoms consist of a mixture of proteins, including the sphingomyelinases D (SMases D), which are the main toxic components responsible for local and systemic effects in human envenomation. Herein, based on the structural informa
Externí odkaz: https://doaj.org/article/71a641201d154ec4a2292fbac0c96f28
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2
Akademický článek
Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities
Autor: Ângela Alice Amadeu Megale, Fábio Carlos Magnoli, Alexandre Kazuo Kuniyoshi, Leo Kei Iwai, Denise V. Tambourgi, Fernanda C. V. Portaro, Wilmar Dias da Silva
Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-11 (2018)
Abstract Background Bitis arietans is a venomous snake found in sub-Saharan Africa and in parts of Morocco and Saudi Arabia. The envenomation is characterized by local and systemic reactions including pain, blistering, edema and tissue damage, beside
Externí odkaz: https://doaj.org/article/7c560881156748fda6edad6cf8d79181
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4
Novel Cysteine Protease Inhibitor Derived from the Haementeria vizottoi Leech: Recombinant Expression, Purification, and Characterization
Autor: Karla Fernanda Ferraz, Débora do Carmo Linhares, Roberto Tadashi Kodama, Dilza Trevisan-Silva, Fernanda C. V. Portaro, Adriane Michele Xavier Prado Amorim, Ana Marisa Chudzinski-Tavassi, Fernanda Faria
Publikováno v: Toxins, Vol 13, Iss 857, p 857 (2021)
Toxins; Volume 13; Issue 12; Pages: 857
Toxins
Cathepsin L (CatL) is a lysosomal cysteine protease primarily involved in the terminal degradation of intracellular and endocytosed proteins. More specifically, in humans, CatL has been implicated in cancer progression and metastasis, as well as coro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f76e3cc1220ded64e93f7545dbbc60f
https://lirias.kuleuven.be/handle/20.500.12942/710326
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5
Akademický článek
Tb II-I, a Fraction Isolated from Tityus bahiensis Scorpion Venom, Alters Cytokines’: Level and Induces Seizures When Intrahippocampally Injected in Rats
Autor: Emidio Beraldo Neto, Douglas O. C. Mariano, Lucas A. Freitas, Ana L. C. Dorce, Adriana N. Martins, Daniel C. Pimenta, Fernanda C. V. Portaro, Daniela Cajado-Carvalho, Valquiria A. C. Dorce, Ana L. A. Nencioni
Publikováno v: Toxins, Vol 10, Iss 6, p 250 (2018)
Scorpion venoms are composed of several substances with different pharmacological activities. Neurotoxins exert their effects by targeting ion channels resulting in toxic effects to mammals, insects and crustaceans. Tb II-I, a fraction isolated from
Externí odkaz: https://doaj.org/article/6c88b0195b4d4e42890cd3c56b4b0a11
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6
Akademický článek
Angiotensin-converting enzyme inhibitors of Bothrops jararaca snake venom affect the structure of mice seminiferous epithelium
Autor: Carlos Alberto-Silva, Joyce M Gilio, Fernanda C. V. Portaro, Samyr M. Querobino, Antonio C. M. Camargo
Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 21, Iss 0 (2015)
Background Considering the similarity between the testis-specific isoform of angiotensin-converting enzyme and the C-terminal catalytic domain of somatic ACE as well as the structural and functional variability of its natural inhibitors, known as bra
Externí odkaz: https://doaj.org/article/4d5473a951954eb2b350c96b03a7fc62
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7
Akademický článek
African adders: partial characterization of snake venoms from three Bitis species of medical importance and their neutralization by experimental equine antivenoms.
Autor: Danielle Paixão-Cavalcante, Alexandre K Kuniyoshi, Fernanda C V Portaro, Wilmar Dias da Silva, Denise V Tambourgi
Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 2, p e0003419 (2015)
BACKGROUND:An alarming number of fatal accidents involving snakes are annually reported in Africa and most of the victims suffer from permanent local tissue damage and chronic disabilities. Envenomation by snakes belonging to the genus Bitis, Viperid
Externí odkaz: https://doaj.org/article/48e5a801e59743a8ba3826071056e2fc
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8
Novel neuroprotective peptides in the venom of the solitary scoliid wasp Scolia decorata ventralis
Autor: Marisa Rangel, Ken-ichi Nihei, Halyne Queiroz Pantaleão, Roberto Tadashi Kodama, Fernanda C. V. Portaro, Carlos Alberto-Silva, Katsuhiro Konno
Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021)
The Journal of Venomous Animals and Toxins Including Tropical Diseases
Journal of Venomous Animals and Toxins including Tropical Diseases v.27 2021
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Background Solitary wasp venoms may be a rich source of neuroactive substances, since their venoms are used for paralyzing preys. We have been exploring bioactive constituents of solitary wasp venoms and, in this study, the component profile of the v
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c4a9e12975625e350f6d0c8ff26be4
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992021000100313&tlng=en
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9
Akademický článek
P-I snake venom metalloproteinase is able to activate the complement system by direct cleavage of central components of the cascade.
Autor: Giselle Pidde-Queiroz, Fábio Carlos Magnoli, Fernanda C V Portaro, Solange M T Serrano, Aline Soriano Lopes, Adriana Franco Paes Leme, Carmen W van den Berg, Denise V Tambourgi
Publikováno v: PLoS Neglected Tropical Diseases, Vol 7, Iss 10, p e2519 (2013)
BACKGROUND: Snake Venom Metalloproteinases (SVMPs) are amongst the key enzymes that contribute to the high toxicity of snake venom. We have recently shown that snake venoms from the Bothrops genus activate the Complement system (C) by promoting direc
Externí odkaz: https://doaj.org/article/b4fe14f815e5401d81604c45a5673115
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10
A Kunitz-type peptide from Dendroaspis polylepis venom as a simultaneous inhibitor of serine and cysteine proteases
Autor: Daniela Cajado-Carvalho, Wilmar Dias da Silva, Cristiane Castilho Fernandes da Silva, Roberto Tadashi Kodama, Douglas Oscar Ceolin Mariano, Bruno Duzzi, Fernanda C. V. Portaro, Daniel C. Pimenta, Alexandre Kazuo Kuniyoshi, Rafael J. Borges
Publikováno v: The Journal of Venomous Animals and Toxins Including Tropical Diseases
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Journal of Venomous Animals and Toxins including Tropical Diseases v.26 2020
The Journal of venomous animals and toxins including tropical diseases
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 26, Article number: e20200037, Published: 07 OCT 2020
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 26 (2020)
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3168b0ed1bfb91546c1b82625953c6
http://europepmc.org/articles/PMC7546081
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