Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Fernanda Bueno, Morrone"'
Autor:
Fernando Mendonça Diz, Wesley F. Monteiro, Iury Santos Silveira, Daniel Ruano, Eduardo Rosa Zotti, Rafael Diogo Weimer, Micael Nunes Melo, João Gabriel Schossler Lopes, Thamiris Becker Scheffel, Linda V. E. Caldas, Jaderson Costa da Costa, Fernanda Bueno Morrone, Rosane Angélica Ligabue
Publikováno v:
ACS Omega, Vol 9, Iss 27, Pp 29499-29515 (2024)
Externí odkaz:
https://doaj.org/article/ddf94d904a034ba28558002d9c7d0862
Autor:
Carla Fernanda Furtado Gardani, Fernando Mendonça Diz, Luísa Brandalise Dondé, Liliana Rockenbach, Stefan Laufer, Fernanda Bueno Morrone
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Purines and pyrimidines are signaling molecules in the tumor microenvironment that affect cancer immunity. The purinergic signaling pathways have been shown to play an important role in the development and progression of cancer. CD39 and CD73 are ect
Externí odkaz:
https://doaj.org/article/a212efaf8ba745b8ad62c31a4f892f44
Autor:
Júlia M. Scopel, Bruna Medeiros-Neves, Helder Ferreira Teixeira, Nathalya T. Brazil, Sérgio A. L. Bordignon, Fernando Mendonça Diz, Fernanda Bueno Morrone, Rafael N. Almeida, Eduardo Cassel, Gilsane L. von Poser, Rubem M. F. Vargas
Publikováno v:
Molecules, Vol 29, Iss 12, p 2741 (2024)
Pterocaulon polystachyum is a species of pharmacological interest for providing volatile and non-volatile extracts with antifungal and amebicidal properties. The biological activities of non-volatile extracts may be related to the presence of coumari
Externí odkaz:
https://doaj.org/article/032ffea9575c4facbbce65cdba9f0b20
Autor:
Carla Fernanda Furtado Gardani, Eduardo Luiz Pedrazza, Victória Santos Paz, Gabriele Goulart Zanirati, Jaderson Costa da Costa, Roberta Andrejew, Henning Ulrich, Juliete Nathali Scholl, Fabrício Figueiró, Liliana Rockenbach, Fernanda Bueno Morrone
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1619 (2023)
Prostate cancer (PC) is the most diagnosed tumor in males and ranks as the second leading cause of male mortality in the western world. The CD39 and CD73 enzymes play a crucial role in cancer regulation by degrading nucleotides and forming nucleoside
Externí odkaz:
https://doaj.org/article/0bb78c94db604bd69bc42c54eca9acfc
Autor:
Nathália Grave, Thamiris Becker Scheffel, Fernanda Fernandes Cruz, Liliana Rockenbach, Márcia Inês Goettert, Stefan Laufer, Fernanda Bueno Morrone
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Gliomas are extremely debilitating malignant brain tumors with very limited response to therapies. The initiation and progression of gliomas can be attributed to several molecular abnormalities, such as mutations in important regulatory networks. In
Externí odkaz:
https://doaj.org/article/9f9d0fbf2ae44aa2aab2855abada4425
Autor:
Thamiris Becker Scheffel, Nathália Grave, Pedro Vargas, Fernando Mendonça Diz, Liliana Rockenbach, Fernanda Bueno Morrone
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Glioblastoma is the most malignant and lethal subtype of glioma. Despite progress in therapeutic approaches, issues with the tumor immune landscape persist. Multiple immunosuppression pathways coexist in the tumor microenvironment, which can determin
Externí odkaz:
https://doaj.org/article/34122b11afcd4de39314cce4b865ee52
Publikováno v:
Molecules, Vol 26, Iss 20, p 6146 (2021)
Gliomas are the most common malignant brain tumors in adults, characterized by a high proliferation and invasion. The tumor microenvironment is rich in growth-promoting signals and immunomodulatory pathways, which increase the tumor’s aggressivenes
Externí odkaz:
https://doaj.org/article/9f798d62b3cf422a8047a5fadc2dfe97
Autor:
Pedro Vargas, Thamiris Becker Scheffel, Fernando Mendonça Diz, Liliana Rockenbach, Nathália Grave, Angélica Regina Cappellari, Luiza Wilges Kist, Maurício Reis Bogo, Marcos Paulo Thomé, Gabriel Fernandes Leal, Amanda de Fraga Dias, Fabrício Figueiró, Eduardo Cremonese Filippi-Chiela, Guido Lenz, Fernanda Bueno Morrone
Publikováno v:
Purinergic Signalling. 18:481-494
Autor:
Barbara Zanesco Moehlecke, Ana Paula Franco Lambert, Angélica Regina Cappellari, Carolina Aiko Moriguchi, Liliana Rockenbach, Daiana Renck, Fernanda Valente Gheler, Julia Brandt de Souza, Fernanda Bueno Morrone, Paula Engroff, Renan Oliveira de Melo
Publikováno v:
Molecular and Cellular Biochemistry. 476:3719-3727
Adenine nucleotides are important signaling molecules that mediate biological functions in many conditions, including cancer. The enzymes CD39 and CD73 produce adenosine in the extracellular milieu that has a very important role in tumor development.
Autor:
Pedro, Vargas, Thamiris Becker, Scheffel, Fernando Mendonça, Diz, Liliana, Rockenbach, Nathália, Grave, Angélica Regina, Cappellari, Luiza Wilges, Kist, Maurício Reis, Bogo, Marcos Paulo, Thomé, Gabriel Fernandes, Leal, Amanda, de Fraga Dias, Fabrício, Figueiró, Eduardo Cremonese, Filippi-Chiela, Guido, Lenz, Fernanda Bueno, Morrone
Publikováno v:
Purinergic Signal
Glioblastoma (GBM) is the most aggressive and lethal among the primary brain tumors, with a low survival rate and resistance to radio and chemotherapy. The P2Y(12) is an adenosine diphosphate (ADP) purinergic chemoreceptor, found mainly in platelets.