Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Fernanda Andreia Rosa"'
1
Akademický článek
Antiparasitic Behavior of Trifluoromethylated Pyrazole 2-Amino-1,3,4-thiadiazole Hybrids and Their Analogues: Synthesis and Structure-Activity Relationship
Autor: Jeniffer do Nascimento Ascencio Camargo, Karlos Eduardo Pianoski, Mariellen Guilherme dos Santos, Danielle Lazarin-Bidóia, Hélito Volpato, Sidnei Moura, Celso Vataru Nakamura, Fernanda Andreia Rosa
Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)
A series of trifluoromethylated pyrazole thiosemicarbazone, trifluromethylated pyrazole isothiosemicarbazone, and trifluoromethylated pyrazole 2-amino-1,3,4-thiadiazole hybrids were synthesized and evaluated in vitro against the promastigote form of
Externí odkaz: https://doaj.org/article/b75f662374724eaeaf97e4b9fe37fc07
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2
Akademický článek
Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles
Autor: Prof. Fernanda Andreia Rosa, Samara Mendes de Souza Melo, Dr. Karlos Eduardo Pianoski, Julia Poletto, Mariellen Guilherme dosSantos, Dr. Michael Jackson Vieira da Silva, Dr. Danielle Lazarin‐Bidóia, Dr. Hélito Volpato, Prof. Sidnei Moura, Prof. Celso Vataru Nakamura
Publikováno v: ChemistryOpen, Vol 10, Iss 10, Pp 931-938 (2021)
Abstract A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases lei
Externí odkaz: https://doaj.org/article/239afcbf39dd485eb5b702be69eab4d1
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6
Estudo estrutural comparativo das 20 CDKs humanas utilizando ferramentas de bioinformática
Autor: Kaique Dias Galera
Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP
As Quinases dependentes de Ciclinas (CDKs) são serina/treonina quinases, cuja atividade é modulada pela interação com ciclinas e sucessivas fosforilações que ocorrem no complexo. Com estudos desde 1980, já é claro que as CDKs atuam como uma d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e666c59ec250c3afa31d286289e1eda
https://doi.org/10.11606/d.75.2020.tde-16032021-155223
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7
Síntese, modelagem molecular e avaliação da atividade anticolinesterásica de N,N-dimetilcarbamatos de cicloexila 3-arilaminossubstituídos
Autor: Yamazaki, Diego Alberto dos Santos
Publikováno v: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Universidade Estadual de Maringá (UEM)
instacron:UEM
The carbamate group has great pharmacological importance as a cholinesterase inhibitor and in the treatment of Alzheimer's disease. The present study describes the synthesis, conformational analysis, assessment of the anticholinesterase activity and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::48d99fab80cdaf77694626e6588c6139
http://repositorio.uem.br:8080/jspui/handle/1/4648
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8
Reciclagem de poli (tereftalato de etileno) (PET) : aplicação tecnológica de etanol supercrítico catalisado por líquidos iônicos [Bmim][BF4] e [HMim][HSO4]
Autor: Nunes, Cátia Santos
Publikováno v: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Universidade Estadual de Maringá (UEM)
instacron:UEM
Poly(ethylene terephthalate) (PET) is a thermoplastic with excellent properties such as mechanical and chemical resistance, thermal stability. Despite its good qualities, PET is not biodegradable and its negligent disposal has been resulting in serio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::ba9066e30ed7e55e3d6345de009196d1
http://repositorio.uem.br:8080/jspui/handle/1/4738
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9
Synthesis and biological in vitro activity of tryptamines and β-carbolines derivatives containing the 4-thiazolidinone ring against human tumor cells and the Herpes simplex type 1 virus and, triazinos-indole for inhibition of DYRK1A related to Alzhei
Autor: Barbosa, Valeria Aquilino
Publikováno v: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Universidade Estadual de Maringá (UEM)
instacron:UEM
Despite the advances in the treatment of the cancer, many of available medicines are not capable to eradicate the cancerous cells without affecting normal tissues. Also, no vaccine or effective antiviral drugs are currently available for prevention/t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::ea618674c9cceeb2d7f36ade500037de
http://repositorio.uem.br:8080/jspui/handle/1/3932
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10
Síntese e avaliação da atividade antitumoral e antiprotozoária de 6-cantinonas contendo unidades arilideno-carboidrazida e alquil-carboxamida na posição-2
Autor: Silva, Camila Mareco Bento Leite
Publikováno v: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Universidade Estadual de Maringá (UEM)
instacron:UEM
The canthin-6-ones are characterized as a subclass of β-carboline alkaloids, with an additional D-ring. This class of compounds displayed important pharmacological activities, such as, antifungal antibacterial, trypanocide, leishmanicide, anti-ulcer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::8560d30517899fe50888dac7407a0211
http://repositorio.uem.br:8080/jspui/handle/1/3906
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