Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Fernanda, Pilataxi"'
Autor:
Koustubh Ranade, Ashok Gupta, Fernanda Pilataxi, Philip Z. Brohawn, Katie Streicher, Christopher A. Morehouse, Brandon W. Higgs
Supplemental Figure S4. Association of IFNγ mRNA signature status and survival in patients with TCGA UC (BLCA), NSCLC adenocarcinoma (LUAD), and squamous NSCLC (LUSC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3d6eeb5cb33fb1dbea3bbfdaeffe68
https://doi.org/10.1158/1078-0432.22474821.v1
https://doi.org/10.1158/1078-0432.22474821.v1
Autor:
Koustubh Ranade, Ashok Gupta, Fernanda Pilataxi, Philip Z. Brohawn, Katie Streicher, Christopher A. Morehouse, Brandon W. Higgs
Purpose: To identify a predictive biomarker for durvalumab, an anti–programmed death ligand 1 (PD-L1) mAb.Experimental Design: RNA sequencing of 97 advanced-stage non–small cell lung carcinoma (NSCLC) biopsies from a nonrandomized phase Ib/II cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bdd43d0fe078220380564fa904d0f02
https://doi.org/10.1158/1078-0432.c.6528918.v1
https://doi.org/10.1158/1078-0432.c.6528918.v1
Autor:
Koustubh Ranade, Ashok Gupta, Fernanda Pilataxi, Philip Z. Brohawn, Katie Streicher, Christopher A. Morehouse, Brandon W. Higgs
Supplemental Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b723bdca16b3ed6cd426b374902ad9f
https://doi.org/10.1158/1078-0432.22474833.v1
https://doi.org/10.1158/1078-0432.22474833.v1
Autor:
Koustubh Ranade, Ashok Gupta, Fernanda Pilataxi, Philip Z. Brohawn, Katie Streicher, Christopher A. Morehouse, Brandon W. Higgs
Supplemental Figure S1. Study design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a582b27d191f7741cb4279febe4d60
https://doi.org/10.1158/1078-0432.22474830.v1
https://doi.org/10.1158/1078-0432.22474830.v1
Autor:
Koustubh Ranade, Ashok Gupta, Fernanda Pilataxi, Philip Z. Brohawn, Katie Streicher, Christopher A. Morehouse, Brandon W. Higgs
Supplemental Figure S3. Association of IFNγ+ signature with OS and PFS at higher cutoffs in NSCLC (A) and UC (B) patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d689a359acd82bd8221a5ff87cf6bdc
https://doi.org/10.1158/1078-0432.22474824.v1
https://doi.org/10.1158/1078-0432.22474824.v1
Autor:
Michael Abadier, Emily Jennings, Jim Eyles, Philip Martin, Fernanda Pilataxi, Yuling Wu, Xiaoru Chen, Analia Azaro, Benjamin Ridgway, Marc Phillips, Benedito Carneiro, Omid Hamid, Thomas Marron, Dmitriy Zamarin, Eduardo Castañón, Sandip Patel, Elena Garralda, Vivek Subbiah, Anthony El-Khoueiry, Paula Fraenkel, Nicholas Durham
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Chih-Hang Anthony Tang, Kristin C. Hicks, Sergei I. Grivennikov, Chih-Chi Andrew Hu, Dmitry I. Gabrilovich, E. John Wherry, Fernanda Pilataxi, Shino Hanabuchi, Corinne Cayatte, Gozde Kar, Kathy Mulgrew, Aimee Landry, Evgenii N. Tcyganov, Brian Dougherty, Ayumi Hashimoto, Yulia Nefedova, David A Campbell, Susana Hayes, Wei Guo, Tim Slidel, Mohammed Alkhatim A. Ali, Jean Christophe Beltra
Publikováno v:
J Clin Invest
Myeloid-derived suppressor cells (MDSCs) are major negative regulators of immune responses in cancer and chronic infections. It remains unclear if regulation of MDSC activity in different conditions is controlled by similar mechanisms. We compared MD
Autor:
Lydia Greenlees, Li Cheng, Bilal Omar, Yelena Lazdun, Jixin Wang, Fernanda Pilataxi, Michael Kuziora, Zachary Cooper, Luis Vence, Katie Streicher
Publikováno v:
Cancer Research. 82:3197-3197
Pancreatic cancer (PDAC) has the highest mortality rate of all major cancers, with few treatment options that provide long-term benefit to patients. Cancer associated fibroblasts (CAFs), the primary cellular component of the pancreatic tumor stroma,
Autor:
Yelena Lazdun, Lydia Greenlees, Song Wu, Nicholas Holoweckyj, Fernanda Pilataxi, Susana Hayes, Brandon Higgs, Katie Streicher
Publikováno v:
Cancer Research. 82:5547-5547
Mutations in the tumor suppressor gene STK11 have been associated with innate resistance to immune checkpoint inhibitors in NSCLC. Although this resistance mechanism is not fully defined, previous work has suggested a role for increased infiltration
Autor:
Fernanda Pilataxi, Lydia Greenlees, Li Cheng, Sriram Sridhar, Todd Creasy, Luis Vence, Katie Streicher
Publikováno v:
Cancer immunology, immunotherapy : CII. 71(5)
The rapid development of immune checkpoint blockade (ICB) therapies has revolutionized the cancer treatment landscape and brightened the long-term forecast for many cancer patients. However, the specific genomic and proteomic changes in tumors treate