Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fernándo González‐Ortiz"'
Autor:
Julia K. Gundersen, Fernando Gonzalez-Ortiz, Thomas Karikari, Bjørn-Eivind Kirsebom, Katrin Mertes, Henrik Zetterberg, Hlin Kvartsberg, Ole Morten Rønning, Berglind Gísladóttir, Kaj Blennow, Tormod Fladby
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100291- (2024)
Introduction: Diagnosis of acute ischemic stroke (AIS) as based on clinical examination and neuroimaging has limitations in determining subgroup aetiology and subsequent long-term motor and cognitive impairment. Identification of high-risk patients e
Externí odkaz:
https://doaj.org/article/91cbf6f4238f40b4a713303257d1f3a9
Autor:
Przemyslaw Radoslaw Kac, Fernándo González‐Ortiz, Joel Simrén, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas K Karikari
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Marc Suárez‐Calvet, Nicholas J. Ashton, Albert Puig‐Pijoan, Marta Milà‐Alomà, Aida Fernández‐Lebrero, Greta García‐Escobar, Fernándo González‐Ortiz, Przemyslaw Radoslaw Kac, Wagner Scheeren Brum, Andréa Lessa Benedet, Juan Lantero Rodriguez, Theresa A. Day, Jeffrey L. Dage, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Gallen Triana‐Baltzer, Setareh Moughadam, Hartmuth C. Kolb, Paula Ortiz‐Romero, Thomas K Karikari, Carolina Minguillón, Juan José Hernández Sánchez, Irene Navalpotro‐Gómez, Oriol Grau‐Rivera, Rosa María Manero, Víctor Puente‐Periz, Rafael de la Torre, Jaume Roquer, Henrik Zetterberg, Kaj Blennow
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Nicholas J. Ashton, Shorena Janelidze, Niklas Mattsson-Carlgren, Alexa Pichet Binette, Olof Strandberg, Wagner S. Brum, Thomas K. Karikari, Fernándo González-Ortiz, Guglielmo Di Molfetta, Francisco J. Meda, Erin M. Jonaitis, Rebecca Langhough Koscik, Karly Cody, Tobey J. Betthauser, Yan Li, Eugeen Vanmechelen, Sebastian Palmqvist, Erik Stomrud, Randall J. Bateman, Henrik Zetterberg, Sterling C. Johnson, Kaj Blennow, Oskar Hansson
Publikováno v:
Nature medicine. 28(12)
Blood biomarkers indicative of Alzheimer’s disease (AD) pathology are altered in both preclinical and symptomatic stages of the disease. Distinctive biomarkers may be optimal for the identification of AD pathology or monitoring of disease progressi
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease
Autor:
Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E. Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M. Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M. Hughes, Marc Suárez-Calvet, Thomas K. Karikari, Tormod Fladby, Kaj Blennow
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates with Aβ patho
Externí odkaz:
https://doaj.org/article/b027901016fa4e8ba7386d92b8d8e45e
Autor:
Przemysław R. Kac, Fernando González-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay R. Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C. Troncoso, Tammaryn Lashley, Gunnar Brinkmalm, Susan M. Resnick, Barbara Mroczko, Hlin Kvartsberg, Milica Gregorič Kramberger, Jörg Hanrieder, Saša Čučnik, Peter Harrison, Henrik Zetterberg, Piotr Lewczuk, Madhav Thambisetty, Uroš Rot, Douglas Galasko, Kaj Blennow, Thomas K. Karikari
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Blood phosphorylated tau (p-tau) biomarkers, including p-tau217, show high associations with Alzheimer’s disease (AD) neuropathologic change and clinical stage. Certain plasma p-tau217 assays recognize tau forms phosphorylated additionally
Externí odkaz:
https://doaj.org/article/cd9a96562fae4bf787bc8b6e650f5603
Autor:
Fernando Gonzalez-Ortiz, Przemysław R. Kac, Wagner S. Brum, Henrik Zetterberg, Kaj Blennow, Thomas K. Karikari
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract As the leading cause of dementia, Alzheimer's disease (AD) is a major burden on affected individuals, their families and caregivers, and healthcare systems. Although AD can be identified and diagnosed by cerebrospinal fluid or neuroimaging b
Externí odkaz:
https://doaj.org/article/a8484e52130d45238e7de04870ee642e
Autor:
Laia Montoliu-Gaya, Daniel Alcolea, Nicholas J. Ashton, Jordi Pegueroles, Johannes Levin, Beatriz Bosch, Juan Lantero-Rodriguez, María Carmona-Iragui, Olivia Wagemann, Mircea Balasa, Przemyslaw Radoslaw Kac, Isabel Barroeta, Albert Lladó, Wagner S. Brum, Laura Videla, Fernando Gonzalez-Ortiz, Bessy Benejam, Javier José Arranz Martínez, Thomas K. Karikari, Georg Nübling, Alexandre Bejanin, Andrea L. Benedet, Rafael Blesa, Alberto Lleó, Kaj Blennow, Raquel Sánchez-Valle, Henrik Zetterberg, Juan Fortea
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104547- (2023)
Summary: Background: The diagnosis of symptomatic Alzheimer's disease is a clinical challenge in adults with Down syndrome. Blood biomarkers would be of particular clinical importance in this population. The astrocytic Glial Fibrillary Acidic Protein
Externí odkaz:
https://doaj.org/article/dad91128d4b14536afd8f3589a5bcde9
Autor:
Przemysław R. Kac, Fernando Gonzalez-Ortiz, Joel Simrén, Nele Dewit, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas K. Karikari
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Blood phosphorylated tau (p-tau) forms are promising Alzheimer’s disease (AD) biomarkers, but validation in matrices other than ethylenediaminetetraacetic acid (EDTA) plasma is limited. Firstly, we assessed the diagnostic potent
Externí odkaz:
https://doaj.org/article/7211e76069b54cb6a47725c40543144e