Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis.

Autor: Zheng K; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; 12 de Octubre Health Research Institute (imas12), Madrid, Spain.; Department of Anesthesiology, Nanjing Pukou District Hospital of Chinese Medicine Central Laboratory affiliated to Nanjing University of Chinese Medicine, Nanjing, China., Hao F; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; 12 de Octubre Health Research Institute (imas12), Madrid, Spain.; Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University, Shanghai, China., Medrano-Garcia S; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Chen C; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; Department of General Surgery, Wuxi Xishan People's Hospital, Wuxi, China.; Department of General Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China., Guo F; Department of Obstetrics and Gynaecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China., Morán-Blanco L; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain., Rodríguez-Perales S; Molecular Cytogenetics and Genome Editing Unit, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain., Torres-Ruiz R; Molecular Cytogenetics and Genome Editing Unit, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain., Peligros MI; Servicio de Anatomía Patológica Hospital General Universitario Gregorio Marañón, Madrid, Spain., Vaquero J; Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain., Bañares R; Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain., Gómez Del Moral M; 12 de Octubre Health Research Institute (imas12), Madrid, Spain.; Department of Cell Biology, Complutense University School of Medicine, Madrid, Spain., Regueiro JR; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Martínez-Naves E; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Mohamed MR; Department of Clinical Medicine III, University Hospital Aachen, UKA, Aachen, Germany., Gallego-Durán R; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Sevilla, Spain., Maya D; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Sevilla, Spain., Ampuero J; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Sevilla, Spain., Romero-Gómez M; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Sevilla, Spain., Gilbert-Ramos A; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Liver Vascular Biology, IDIBAPS Biomedical Research Institute, Barcelona, Spain., Guixé-Muntet S; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Liver Vascular Biology, IDIBAPS Biomedical Research Institute, Barcelona, Spain., Fernández-Iglesias A; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Liver Vascular Biology, IDIBAPS Biomedical Research Institute, Barcelona, Spain., Gracia-Sancho J; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Liver Vascular Biology, IDIBAPS Biomedical Research Institute, Barcelona, Spain.; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Coll M; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Laboratorio de Plasticidad de Células Hepáticas y Reparación de Tejidos, Institut d´Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Graupera I; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Laboratorio de Plasticidad de Células Hepáticas y Reparación de Tejidos, Institut d´Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Liver Unit, Hospital Clinic, Barcelona, Spain., Ginès P; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Liver Unit, Hospital Clinic, Barcelona, Spain., Ciudin A; Endocrinology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute for Research (VHIR), Barcelona, Spain., Rivera-Esteban J; Liver Unit, Internal Medicine Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute for Research (VHIR), Barcelona, Spain., Pericàs JM; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Liver Unit, Internal Medicine Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute for Research (VHIR), Barcelona, Spain., Frutos MD; Department of General and Digestive System Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain., Ramos Molina B; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Laboratorio de Obesidad y Metabolismo, Instituto de Investigación Biomédica de Murcia (IMIB-Arrixaca), Murcia, Spain., Herranz JM; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Hepatology Programme, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; IdiSNA, Navarra Institute for Health Research, Pamplona, Spain., Ávila MA; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Hepatology Programme, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; IdiSNA, Navarra Institute for Health Research, Pamplona, Spain., Nevzorova YA; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain., Fernández-Malavé E; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain.; 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Cubero FJ; Department of Immunology, Ophthalmology & ENT, Complutense University School of Medicine, Madrid, Spain. fcubero@ucm.es.; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain. fcubero@ucm.es.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain. fcubero@ucm.es.

Publikováno v: Cell death & disease [Cell Death Dis] 2023 Aug 10; Vol. 14 (8), pp. 514. Date of Electronic Publication: 2023 Aug 10.

HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape.

Autor: Medrano-Garcia S; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.; Institute for Lung Health (ILH), Justus Liebig University, 35305 Giessen, Germany.; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28040 Madrid, Spain., Morales-Cano D; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid and Instituto de Investigación Sanitaria Gregorio Marañón, Centro de Investigación Biomédica en Red Enfermedades Respiratorias, 28040 Madrid, Spain.; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28040 Madrid, Spain., Barreira B; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid and Instituto de Investigación Sanitaria Gregorio Marañón, Centro de Investigación Biomédica en Red Enfermedades Respiratorias, 28040 Madrid, Spain., Vera-Zambrano A; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid and Instituto de Investigación Sanitaria Gregorio Marañón, Centro de Investigación Biomédica en Red Enfermedades Respiratorias, 28040 Madrid, Spain., Kumar R; Department of Medicine, University of California, San Francisco, CA 94143, USA., Kosanovic D; Department of Pulmonology, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia., Schermuly RT; Department of internal Medicine, Justus-Liebig University, Member of the German Center for Lung Research (DZL), 35305 Giessen, Germany., Graham BB; Department of Medicine, University of California, San Francisco, CA 94143, USA., Perez-Vizcaino F; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid and Instituto de Investigación Sanitaria Gregorio Marañón, Centro de Investigación Biomédica en Red Enfermedades Respiratorias, 28040 Madrid, Spain., Mathie A; Medway School of Pharmacy, University of Kent and University of Greenwich, Chatham ME4 4BF, UK., Savai R; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.; Institute for Lung Health (ILH), Justus Liebig University, 35305 Giessen, Germany.; Department of internal Medicine, Justus-Liebig University, Member of the German Center for Lung Research (DZL), 35305 Giessen, Germany., Pullamseti S; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.; Institute for Lung Health (ILH), Justus Liebig University, 35305 Giessen, Germany.; Department of internal Medicine, Justus-Liebig University, Member of the German Center for Lung Research (DZL), 35305 Giessen, Germany., Butrous G; Medway School of Pharmacy, University of Kent and University of Greenwich, Chatham ME4 4BF, UK., Fernández-Malavé E; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28040 Madrid, Spain., Cogolludo A; Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid and Instituto de Investigación Sanitaria Gregorio Marañón, Centro de Investigación Biomédica en Red Enfermedades Respiratorias, 28040 Madrid, Spain.

Publikováno v: Cells [Cells] 2022 Aug 04; Vol. 11 (15). Date of Electronic Publication: 2022 Aug 04.

CD3G or CD3D Knockdown in Mature, but Not Immature, T Lymphocytes Similarly Cripples the Human TCRαβ Complex.

Autor: Garcillán B; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Fuentes P; Interaction with the Environment Program, Immune System Development and Function Unit, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain., Marin AV; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Megino RF; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Chacon-Arguedas D; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Mazariegos MS; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Jiménez-Reinoso A; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Muñoz-Ruiz M; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Laborda RG; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Cárdenas PP; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Fernández-Malavé E; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Toribio ML; Interaction with the Environment Program, Immune System Development and Function Unit, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain., Regueiro JR; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 Jun 25; Vol. 9, pp. 608490. Date of Electronic Publication: 2021 Jun 25 (Print Publication: 2021).

Human plasma C3 is essential for the development of memory B, but not T, lymphocytes.

Autor: Jiménez-Reinoso A; Department of Immunology, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Marin AV; Department of Immunology, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Subias M; Centro de Investigaciones Biológicas (CSIC), Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain., López-Lera A; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain; Immunology Unit, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain., Román-Ortiz E; Servicio de Nefrología Pediátrica, Hospital La Fe, Valencia, Spain., Payne K; Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, Australia., Ma CS; Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, Australia., Arbore G; MRC Centre for Transplantation, Division of Transplant Immunology and Mucosal Biology, King's, College London, London, United Kingdom., Kolev M; MRC Centre for Transplantation, Division of Transplant Immunology and Mucosal Biology, King's, College London, London, United Kingdom., Freeley SJ; MRC Centre for Transplantation, Division of Transplant Immunology and Mucosal Biology, King's, College London, London, United Kingdom., Kemper C; MRC Centre for Transplantation, Division of Transplant Immunology and Mucosal Biology, King's, College London, London, United Kingdom., Tangye SG; Immunology Research Program, Garvan Institute of Medical Research, Darlinghurst, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, Australia., Fernández-Malavé E; Department of Immunology, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain., Rodríguez de Córdoba S; Centro de Investigaciones Biológicas (CSIC), Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain., López-Trascasa M; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain; Immunology Unit, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain., Regueiro JR; Department of Immunology, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain. Electronic address: regueiro@med.ucm.es.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2018 Mar; Vol. 141 (3), pp. 1151-1154.e14. Date of Electronic Publication: 2017 Nov 04.

Human Invariant Natural Killer T Cells Respond to Antigen-Presenting Cells Exposed to Lipids from Olea europaea Pollen.

Autor: Abos Gracia B; Department of Immunology, Faculty of Medicine, and 12 de Octubre Health Research Institute (imas12), Complutense University, Madrid, Spain., López Relaño J, Revilla A, Castro L, Villalba M, Martín Adrados B, Regueiro JR, Fernández-Malavé E, Martínez Naves E, Gómez Del Moral M

Publikováno v: International archives of allergy and immunology [Int Arch Allergy Immunol] 2017; Vol. 173 (1), pp. 12-22. Date of Electronic Publication: 2017 May 10.