Výsledky vyhledávání - "Fernández Braña, Alfredo Javier"

The chromomycin CmmA acetyltransferase: a membrane‐bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

Autor: García Fernández, Beatriz, González Sabín, Javier, Menéndez Sánchez, Nuria, Fernández Braña, Alfredo Javier, Núñez González, Luz Elena, Morís Varas, Francisco, Salas Fernández, José Antonio, Méndez Fernández, María del Carmen

Publikováno v: Microbial Biotechnology
WILEY
RUO. Repositorio Institucional de la Universidad de Oviedo
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Summary Mithramycin and chromomycin A3 are two structurally related antitumour compounds, which differ in the glycosylation profiles and functional group substitutions of the sugars. Chromomycin contains two acetyl groups, which are incorporated duri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::07ecb83225e15366e2e7e7f945aab20e
http://europepmc.org/articles/PMC3818863

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Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055Cluster Analysis and Assignment of Functions

Autor: Olano Álvarez, Carlos, Wilkinson, Barrie M., Sánchez Reillo, César, Moss, Steven J., Sheridan, Rose M., Math, Vidya, Weston, Alison J., Fernández Braña, Alfredo Javier, Martin, Christine J., Oliynyk, Markiyan, Méndez Fernández, María del Carmen, Leadlay, Peter F., Salas Fernández, José Antonio

Publikováno v: Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname

The biosynthetic gene cluster for the angiogenesis inhibitor borrelidin has been cloned from Streptomyces parvulus Tü4055. Sequence analysis indicates that the macrolide ring of borrelidin is formed by a modular polyketide synthase (PKS) (borA1-A6),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc89364ec021bb14cc8a45346b6a6e1
https://doi.org/10.1016/s1074-5521(03)00297-7

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Myxococcus xanthus induces actinorhodin overproduction and aerial mycelium formation by Streptomyces coelicolor

Autor: Pérez, Juana, Muñoz-Dorado, José, Fernández Braña, Alfredo Javier, Shimkets, Lawrence J., Sevillano, Laura, Santamaría, Ramón

Publikováno v: WILEY
RUO. Repositorio Institucional de la Universidad de Oviedo
instname

This work has been supported by grants from Ministerio de Ciencia e Innovación (EUI2008-03631 to R.I.S.; BFU2009-07565/BMC, 70% funded by FEDER, and the programme CONSOLIDER-INGENIO 2010, CSD2009-00006, both to J.M.-D.), Spain. This material is base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c80873367dbe018dc6a2c82dc9b38f93
http://hdl.handle.net/10651/8567

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The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster

Autor: Lombó Brugos, Felipe, Fernández Braña, Alfredo Javier, Méndez Fernández, María del Carmen, Salas Fernández, José Antonio

Publikováno v: Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname

Research at the authors’ laboratory has been supported by grants from the Spanish Ministry of Education and Science (BMC2002-03599 and BIO2005-04115 to C. Méndez) and by a grant from the Plan Regional de Investigación del Principado de Asturias (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6c714237a5b640f44084d27f2f6fbd51
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032902411&partnerID=40&md5=7704384ecc256634420f824d4748cbef

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