Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Fernán, Agüero"'
Autor:
Nieves Martínez-Peinado, Juan Carlos Gabaldón-Figueira, Roberto Rodrigues Ferreira, María Carmen Thomas, Manuel Carlos López, Tania Cremonini Araújo-Jorge, Belkisyolé Alarcón de Noya, Soledad Berón, Janine Ramsey, Irene Losada Galván, Alejandro Gabriel Schijman, Adriana González Martínez, Andrés Mariano Ruiz, Gimena Rojas, Roberto Magalhães Saraiva, Oscar Noya-González, Andrea Gómez, Rosa A Maldonado, Jimmy Pinto, Faustino Torrico, Ivan Scandale, Fernán Agüero, María-Jesús Pinazo, Joaquim Gascón, Alejandro Marcel Hasslocher-Moreno, Julio Alonso-Padilla, NHEPACHA Network (New Tools for the Diagnosis and Evaluation of Chagas Disease)
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012166 (2024)
Chagas disease, caused by the parasite Trypanosoma cruzi, affects over 6 million people, mainly in Latin America. Two different clinical phases, acute and chronic, are recognised. Currently, 2 anti-parasitic drugs are available to treat the disease (
Externí odkaz:
https://doaj.org/article/542e8f3288c8497496fa6fd2380b1886
Autor:
Alejandro D. Ricci, Leonel Bracco, Emir Salas-Sarduy, Janine M. Ramsey, Melissa S. Nolan, M. Katie Lynn, Jaime Altcheh, Griselda E. Ballering, Faustino Torrico, Norival Kesper, Juan C. Villar, Iván S. Marcipar, Jorge D. Marco, Fernán Agüero
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
This work reveals the diversity and extent of human antibody specificities in Chagas disease and provides a wealth of well-defined antigenic markers for diagnosis and development of serological applications for this neglected infectious disease.
Externí odkaz:
https://doaj.org/article/ef44d0c123244e7894dd34b27c90789c
Autor:
Guadalupe Romer, Leonel A Bracco, Alejandro D Ricci, Virginia Balouz, Luisa Berná, Juan C Villar, Janine M Ramsey, Melissa S Nolan, Faustino Torrico, Norival Kesper, Jaime Altcheh, Carlos Robello, Carlos A Buscaglia, Fernán Agüero
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 8, p e0011542 (2023)
BackgroundTrypanosoma cruzi, the agent of Chagas disease, displays a highly structured population, with multiple strains that can be grouped into 6-7 evolutionary lineages showing variable eco-epidemiological traits and likely also distinct disease-a
Externí odkaz:
https://doaj.org/article/579e0e5b9dd54fdb88080b19cef82008
Autor:
Santiago José Martinez, Gonzalo Nicolás Nardella, Matías Exequiel Rodríguez, Cynthia Vanesa Rivero, Fernán Agüero, Patricia Silvia Romano
Publikováno v:
Current Research in Microbial Sciences, Vol 3, Iss , Pp 100152- (2022)
Trypanosoma cruzi, the etiologic agent of Chagas disease (CD) presents a wide genetic and phenotypic diversity that is classified into seven lineages or discrete typing units (DTU: TcI to TcVI and Tcbat). Although isolates and strains that belong to
Externí odkaz:
https://doaj.org/article/0bc72dce63dd459f8e3671d25bda4f32
Autor:
Alejandro D. Ricci, Mauricio Brunner, Diego Ramoa, Santiago J. Carmona, Morten Nielsen, Fernán Agüero
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Availability of highly parallelized immunoassays has renewed interest in the discovery of serology biomarkers for infectious diseases. Protein and peptide microarrays now provide a rapid, high-throughput platform for immunological testing and validat
Externí odkaz:
https://doaj.org/article/8624bb43e28f4d54ab53216e0ef67bf9
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Exploration and processing of FASTQ files are the first steps in state-of-the-art data analysis workflows of Next Generation Sequencing (NGS) platforms. The large amount of data generated by these technologies has put a challenge
Externí odkaz:
https://doaj.org/article/ce54e9a642994acfb2d95d6bd4e9e8f5
Autor:
Emir Salas-Sarduy, Lionel Urán Landaburu, Adriana K Carmona, Juan José Cazzulo, Fernán Agüero, Vanina E Alvarez, Gabriela T Niemirowicz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007560 (2019)
Enzymes of the M32 family are Zn-dependent metallocarboxypeptidases (MCPs) widely distributed among prokaryotic organisms and just a few eukaryotes including Trypanosoma brucei and Trypanosoma cruzi, the causative agents of sleeping sickness and Chag
Externí odkaz:
https://doaj.org/article/543d4537552f4bd390a287dae8164735
Autor:
Maite Lobo, Virginia Balouz, Luciano Melli, Giannina Carlevaro, María E Cortina, María de Los Milagros Cámara, Gaspar E Cánepa, Santiago J Carmona, Jaime Altcheh, Oscar Campetella, Andrés E Ciocchini, Fernán Agüero, Juan Mucci, Carlos A Buscaglia
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007245 (2019)
BACKGROUND:TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors. Preliminary biochemical studies indicated that TolT resolved in SDS-PAG
Externí odkaz:
https://doaj.org/article/084386b17edb44459ea0f1c8f4f44583
Publikováno v:
Biochemical Society transactions.
Trypanosomatids are protozoan parasites that cause human and animal neglected diseases. Despite global efforts, effective treatments are still much needed. Phenotypic screens have provided several chemical leads for drug discovery, but the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e379683cc360b88723f3a432f6002d52
https://pubmed.ncbi.nlm.nih.gov/36606702
https://pubmed.ncbi.nlm.nih.gov/36606702
Autor:
Juan Mucci, Santiago J Carmona, Romina Volcovich, Jaime Altcheh, Estefanía Bracamonte, Jorge D Marco, Morten Nielsen, Carlos A Buscaglia, Fernán Agüero
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0005972 (2017)
Chagas Disease, caused by the protozoan Trypanosoma cruzi, is a major health and economic problem in Latin America for which no vaccine or appropriate drugs for large-scale public health interventions are yet available. Accurate diagnosis is essentia
Externí odkaz:
https://doaj.org/article/05db6acf4bbe4db5976c14a785c4ac5a