Scratching the Surface Takes a Toll: Immune Recognition of Viral Proteins by Surface Toll-like Receptors

Autor: Alexis A. Hatton, Fermin E. Guerra

Publikováno v: Viruses, Vol 15, Iss 1, p 52 (2022)

Early innate viral recognition by the host is critical for the rapid response and subsequent clearance of an infection. Innate immune cells patrol sites of infection to detect and respond to invading microorganisms including viruses. Surface Toll-lik

Externí odkaz: https://doaj.org/article/7d1c5d0d4f9c46e0bb2ffe3e08e6c255

Aspartic Acid Residue 51 of SaeR Is Essential for Staphylococcus aureus Virulence

Autor: Tyler K. Nygaard, Timothy R. Borgogna, Eli W. Sward, Fermin E. Guerra, Jennifer G. Dankoff, Madison M. Collins, Kyler B. Pallister, Liang Chen, Barry N. Kreiswirth, Jovanka M. Voyich

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Staphylococcus aureus is a common Gram-positive bacteria that is a major cause of human morbidity and mortality. The SaeR/S two-component sensory system of S. aureus is important for virulence gene transcription and pathogenesis. However, the influen

Externí odkaz: https://doaj.org/article/a9ef3d4c0d7448a5ad008a054beeb343

The Accessory Gene saeP of the SaeR/S Two-Component Gene Regulatory System Impacts Staphylococcus aureus Virulence During Neutrophil Interaction

Autor: Tyler K. Nygaard, Jennifer G. Dankoff, Shaun R. Brinsmade, Brock Cone, Madison M. Collins, Tyler J. Evans, Jovanka M. Voyich, Willis Pullman, Owen Burroughs, Ranjan K. Behera, Caralyn E. Flack, Kyler B. Pallister, Fermin E. Guerra

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Staphylococcus aureus (S. aureus) causes a range of diseases ranging from superficial skin and soft-tissue infections to invasive and life-threatening conditions (Klevens et al., 2007; Kobayashi et al., 2015). S. aureus utilizes the Sae sensory syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d321c7aa8d545fce05de6bb04636f53c
https://www.frontiersin.org/article/10.3389/fmicb.2020.00561/full

The Accessory Gene

Autor: Madison M, Collins, Ranjan K, Behera, Kyler B, Pallister, Tyler J, Evans, Owen, Burroughs, Caralyn, Flack, Fermin E, Guerra, Willis, Pullman, Brock, Cone, Jennifer G, Dankoff, Tyler K, Nygaard, Shaun R, Brinsmade, Jovanka M, Voyich

Publikováno v: Frontiers in Microbiology

Staphylococcus aureus (S. aureus) causes a range of diseases ranging from superficial skin and soft-tissue infections to invasive and life-threatening conditions (Klevens et al., 2007; Kobayashi et al., 2015). S. aureus utilizes the Sae sensory syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::82be66af5700355540af8972b03b47f3
https://pubmed.ncbi.nlm.nih.gov/32390958

Immune evasion by a staphylococcal inhibitor of myeloperoxidase

Autor: Alex J. McCarthy, Nienke W.M. de Jong, Fermin E. Guerra, Kasra X. Ramyar, Pieter Jan Haas, Kok P. M. van Kessel, Cindy Fevre, Reindert Nijland, Jos A. G. van Strijp, Jovanka M. Voyich, Brian V. Geisbrecht, Brandon L. Garcia

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 114(35), 9439
Proceedings of the National Academy of Sciences of the United States of America, 114(35), 9439-9444
Proceedings of the National Academy of Sciences of the United States of America 114 (2017) 35

Staphylococcus aureus is highly adapted to its host and has evolved many strategies to resist opsonization and phagocytosis. Even after uptake by neutrophils, S. aureus shows resistance to killing, which suggests the presence of phagosomal immune eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df1c08bc4108083bf98d390f13eba13
https://doi.org/10.1073/pnas.1707032114