Bacterial stigmasterol degradation involving radical flavin delta-24 desaturase and molybdenum-dependent C26 hydroxylase.

Autor: Zhan T; Faculty of Biology, Department of Microbiology, University of Freiburg, Freiburg, Germany., Jacoby C; Faculty of Biology, Department of Microbiology, University of Freiburg, Freiburg, Germany., Jede M; Faculty of Biology, Department of Microbiology, University of Freiburg, Freiburg, Germany., Knapp B; Faculty of Biology, Department of Biochemistry and Functional Proteomics, University of Freiburg, Freiburg, Germany., Ferlaino S; Institute of Pharmaceutical Sciences, University of Freiburg, Freiburg, Germany., Günter A; Institute of Physical Chemistry, University of Freiburg, Freiburg, Germany., Drepper F; Faculty of Biology, Department of Biochemistry and Functional Proteomics, University of Freiburg, Freiburg, Germany., Müller M; Institute of Pharmaceutical Sciences, University of Freiburg, Freiburg, Germany., Weber S; Institute of Physical Chemistry, University of Freiburg, Freiburg, Germany., Boll M; Faculty of Biology, Department of Microbiology, University of Freiburg, Freiburg, Germany. Electronic address: matthias.boll@biologie.uni-freiburg.de.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 May; Vol. 300 (5), pp. 107243. Date of Electronic Publication: 2024 Mar 30.

Extended substrate range of thiamine diphosphate-dependent MenD enzyme by coupling of two C-C-bonding reactions.

Autor: Schapfl M; Institute of Microbiology, Universität Stuttgart, Allmandring 31, 70569, Stuttgart, Germany., Baier S; Institute of Microbiology, Universität Stuttgart, Allmandring 31, 70569, Stuttgart, Germany., Fries A; Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Ferlaino S; Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Waltzer S; Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Müller M; Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Sprenger GA; Institute of Microbiology, Universität Stuttgart, Allmandring 31, 70569, Stuttgart, Germany. Georg.sprenger@imb.uni-stuttgart.de.

Publikováno v: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2018 Oct; Vol. 102 (19), pp. 8359-8372. Date of Electronic Publication: 2018 Jul 31.

Extended Catalytic Scope of a Well-Known Enzyme: Asymmetric Reduction of Iminium Substrates by Glucose Dehydrogenase.

Autor: Roth S; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Präg A; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Wechsler C; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Marolt M; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Ferlaino S; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Lüdeke S; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany., Sandon N; Process Chemistry and Catalysis, F. Hoffmann-La Roche, Ltd., 4070, Basel, Switzerland., Wetzl D; Process Chemistry and Catalysis, F. Hoffmann-La Roche, Ltd., 4070, Basel, Switzerland., Iding H; Process Chemistry and Catalysis, F. Hoffmann-La Roche, Ltd., 4070, Basel, Switzerland., Wirz B; Process Chemistry and Catalysis, F. Hoffmann-La Roche, Ltd., 4070, Basel, Switzerland., Müller M; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104, Freiburg, Germany.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2017 Sep 05; Vol. 18 (17), pp. 1703-1706. Date of Electronic Publication: 2017 Jul 19.

Genome mining and biosynthetic pathways of marine-derived fungal bioactive natural products.

Autor: Han, Caihua, Song, Anjing, He, Yueying, Yang, Liu, Chen, Litong, Dai, Wei, Wu, Qilin, Yuan, Siwen

Publikováno v: Frontiers in Microbiology; 2024, p1-28, 28p

Tautomers of anthrahydroquinones: enzymatic reduction and implications for chrysophanol, monodictyphenone, and related xanthone biosyntheses.

Autor: Schätzle MA; Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104 Freiburg, Germany., Husain SM, Ferlaino S, Müller M

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2012 Sep 12; Vol. 134 (36), pp. 14742-5. Date of Electronic Publication: 2012 Aug 28.