Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ferguson Stephen SG"'
Autor:
Lorenzen Angela, Samosh Jonathan, Vandewark Kenneth, Anborgh Pieter H, Seah Claudia, Magalhaes Ana C, Cregan Sean P, Ferguson Stephen SG, Pasternak Stephen H
Publikováno v:
Molecular Brain, Vol 3, Iss 1, p 11 (2010)
Abstract Background A central feature of Alzheimer's disease is the cleavage of the amyloid precursor protein (APP) to form beta-amyloid peptide (Aβ) by the β-secretase and γ-secretase enzymes. Although this has been shown to occur after endocytos
Externí odkaz:
https://doaj.org/article/aec0b9aea70e4f7092a02b4732a07759
Pyk2 uncouples metabotropic glutamate receptor G protein signaling but facilitates ERK1/2 activation
Autor:
Nicodemo Alexander A, Pampillo Macarena, Ferreira Lucimar T, Dale Lianne B, Cregan Tamara, Ribeiro Fabiola M, Ferguson Stephen SG
Publikováno v:
Molecular Brain, Vol 3, Iss 1, p 4 (2010)
Abstract Group I metabotropic glutamate receptors (mGluRs) are coupled via Gαq/11 to the activation of phospholipase Cβ, which hydrolyzes membrane phospholipids to form inositol 1,4,5 trisphosphate and diacylglycerol. This results in the release of
Externí odkaz:
https://doaj.org/article/d60b2d0ee0714124857a072da49af26a
GPCRs represent the largest family of integral membrane proteins and were first identified as receptor proteins that couple via heterotrimeric G-proteins to regulate a vast variety of effector proteins to modulate cellular function. It is now recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56859d29dac922be51cbacd27305d6b8
https://europepmc.org/articles/PMC3372825/
https://europepmc.org/articles/PMC3372825/
Autor:
Guimaraes IM; Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901, Brazil. pandoraufmg@gmail.com., Carvalho TG; Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901, Brazil. toniana_gc@hotmail.com., Ferguson SS; J. Allyn Taylor Centre for Cell Biology, Robarts Research Institute, University of Western Ontario, London, Ontario, N6A 5 K8, Canada. ferguson@robarts.ca., Pereira GS; Nucleo de Neurociencias, Departamento de Fisiologia e Biofisica, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901, Brazil. graceschenatto@gmail.com., Ribeiro FM; Departamento de Bioquimica e Imunologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901, Brazil. fmribeiro@icb.ufmg.br.
Publikováno v:
Molecular brain [Mol Brain] 2015 Apr 10; Vol. 8, pp. 24. Date of Electronic Publication: 2015 Apr 10.
Autor:
Ribeiro FM; Universidade Federal de Minas Gerais, Departamento de Bioquimica e Imunologia, ICB , Belo Horizonte 31270-901 , Brazil rfabiola26@hotmail.com., Hamilton A, Doria JG, Guimaraes IM, Cregan SP, Ferguson SS
Publikováno v:
Expert opinion on therapeutic targets [Expert Opin Ther Targets] 2014 Nov; Vol. 18 (11), pp. 1293-304. Date of Electronic Publication: 2014 Aug 14.
Autor:
Magalhaes AC; J. Allyn Taylor Centre for Cell Biology, Molecular Brain Research Group, Robarts Research Institute, London, ON, CanadaThe Department of Physiology & Pharmacology, the University of Western Ontario, London, ON, Canada., Dunn H; J. Allyn Taylor Centre for Cell Biology, Molecular Brain Research Group, Robarts Research Institute, London, ON, CanadaThe Department of Physiology & Pharmacology, the University of Western Ontario, London, ON, Canada., Ferguson SS; J. Allyn Taylor Centre for Cell Biology, Molecular Brain Research Group, Robarts Research Institute, London, ON, CanadaThe Department of Physiology & Pharmacology, the University of Western Ontario, London, ON, Canada.
Publikováno v:
British journal of pharmacology [Br J Pharmacol] 2012 Mar; Vol. 165 (6), pp. 1717-1736.