Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fergus W Hamilton"'
Autor:
Fergus W Hamilton, Matt Thomas, David Arnold, Tom Palmer, Ed Moran, Alexander J Mentzer, Nick Maskell, Kenneth Baillie, Charlotte Summers, Aroon Hingorani, Alasdair MacGowan, Golam M Khandaker, Ruth Mitchell, George Davey Smith, Peter Ghazal, Nicholas J Timpson
Publikováno v:
PLoS Medicine, Vol 20, Iss 1, p e1004174 (2023)
BackgroundSepsis is characterised by dysregulated, life-threatening immune responses, which are thought to be driven by cytokines such as interleukin 6 (IL-6). Genetic variants in IL6R known to down-regulate IL-6 signalling are associated with improv
Externí odkaz:
https://doaj.org/article/2608ebec05cb45ed9c68e5978c195d71
Autor:
Tom Dudding, Sadiyah Sheikh, Florence Gregson, Jennifer Haworth, Simon Haworth, Barry G Main, Andrew J Shrimpton, Fergus W Hamilton, AERATOR group, Anthony J Ireland, Nick A Maskell, Jonathan P Reid, Bryan R Bzdek, Mark Gormley
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265076 (2022)
Aerosol generating procedures (AGPs) are defined as any procedure releasing airborne particles
Externí odkaz:
https://doaj.org/article/10429ec4dd1b4c9a912d4a5765d0e4a9
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0267399 (2022)
IntroductionHeme-oxygenase 1 (HMOX1) is a critical stress response gene that catalyzes the multistep oxidation of heme. A GT(n) repeat of variable length in the promoter in has been associated with a wide range of human diseases, including infections
Externí odkaz:
https://doaj.org/article/4af1142a787b4459a87a7e89b2b9ecce
Autor:
Frances Edwards, Fergus W Hamilton
Publikováno v:
Edwards, F & Hamilton, F W 2023, ' Impact of covid-19 vaccination on long covid ', BMJ Medicine, vol. 2, no. 1, e000470 . https://doi.org/10.1136/bmjmed-2022-000470
[No abstract]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8827c41a548082abb17490dc4b91e1e8
https://research-information.bris.ac.uk/en/publications/b527cfda-1d99-441f-8e5f-c6e91edcb4b1
https://research-information.bris.ac.uk/en/publications/b527cfda-1d99-441f-8e5f-c6e91edcb4b1
Autor:
Fergus W. Hamilton, Matt Thomas, David Arnold, Tom Palmer, Ed Moran, Alexander J. Mentzer, Nick Maskell, Kenneth Baillie, Charlotte Summers, Aroon Hingorani, Alasdair MacGowan, Golam M. Khandaker, Ruth Mitchell, George Davey Smith, Peter Ghazal, Nicholas J. Timpson
Publikováno v:
Hamilton, F W, Thomas, M, Arnold, D, Palmer, T, Moran, E, Mentzer, A J, Maskell, N, Baillie, K, Summers, C, Hingorani, A, MacGowan, A, Khandaker, G M, Mitchell, R, Davey Smith, G, Ghazal, P & Timpson, N J 2023, ' Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death : A mendelian randomisation study ', PLoS Medicine, vol. 20, no. 1, e1004174 . https://doi.org/10.1371/journal.pmed.1004174
Funder: Oxford Biomedical Research Centre
Funder: EU-ERDF
Funder: Wellcome Trust; funder-id: http://dx.doi.org/10.13039/100010269
Funder: GlaxoSmithKline; funder-id: http://dx.doi.org/10.13039/100004330
Funder: Sepsis Research
Funder: EU-ERDF
Funder: Wellcome Trust; funder-id: http://dx.doi.org/10.13039/100010269
Funder: GlaxoSmithKline; funder-id: http://dx.doi.org/10.13039/100004330
Funder: Sepsis Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f42432e8c6ea2ae4f9de78a1e1360c1
Autor:
Tosti J. Mankelow, Allison Blair, David T. Arnold, Fergus W. Hamilton, Kathleen M. Gillespie, David J. Anstee, Ashley M. Toye
Publikováno v:
Mankelow, T J, Blair, A, Arnold, D T, Hamilton, F W, Gillespie, K M, Anstee, D J & Toye, A M 2022, ' Higher levels of von Willebrand Factor in hospitalised patient plasma provides an explanation for the association of ABO blood group and secretor status with COVID19 severity ', Transfusion Medicine, vol. 32, no. 3, pp. 261-262 . https://doi.org/10.1111/tme.12860
[No abstract]
IntroductionDexamethasone has been shown to reduce mortality for patients hospitalised with acute COVID-19 pneumonia. However, a significant proportion of patients suffer persistent symptoms following COVID-19 and little is known about the longer-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdddc210134305dae75023c312f9614
https://doi.org/10.1101/2021.11.17.21266392
https://doi.org/10.1101/2021.11.17.21266392
Autor:
Tom, Dudding, Sadiyah, Sheikh, Florence, Gregson, Jennifer, Haworth, Simon, Haworth, Barry G, Main, Andrew J, Shrimpton, Fergus W, Hamilton, Anthony J, Ireland, Nick A, Maskell, Jonathan P, Reid, Bryan R, Bzdek, Mark, Gormley
Publikováno v:
Dudding, T, Sheikh, S, Gregson, F K A, Haworth, J A, Haworth, S J, Main, B G J, Shrimpton, A J, Hamilton, F W, Ireland, A J, Maskell, N A, Reid, J P, Bzdek, B R & Gormley, M 2022, ' A clinical observational analysis of aerosol emissions from dental procedures ', PLoS ONE, vol. 17, no. 3, e0265076 . https://doi.org/10.1371/journal.pone.0265076
Aerosol generating procedures (AGPs) are defined as any procedure releasing airborne particles σ)) and peak positions (DP,C)). The aerosol size distribution provided a robust fingerprint of aerosol emission from a source. 41 patients underwent fifte
Publikováno v:
Hamilton, F W, Evans, R N, Ghazal, P & Macgowan, A P 2021, ' Time-to-positivity in bloodstream infection is not a prognostic marker for mortality : analysis of a prospective multicentre randomized control trial ', Clinical Microbiology and Infection, vol. 28, no. 1, pp. 136.e7-136.e13 . https://doi.org/10.1016/j.cmi.2021.05.043
Objectives Time to positivity (TTP), calculated automatically in modern blood culture systems, is considered a proxy for microbial load and has been suggested as a potential prognostic marker in bloodstream infections. In this large, multicentre, pro