Zobrazeno 1 - 10
of 899
pro vyhledávání: '"Fergus, Shanahan"'
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Irritable bowel syndrome (IBS) is a prevalent disorder of gut‐brain interaction without a reliable cure. Evidence suggests that an alteration of the gut microbiome may contribute to IBS pathogenesis, motivating the development of microbiom
Externí odkaz:
https://doaj.org/article/c7f310bd542f4080801b29a4749a9d6a
Autor:
Raminder Singh, Valerio Rossini, Stephen R. Stockdale, Gonzalo Saiz-Gonzalo, Naomi Hanrahan, Tanya D’ Souza, Adam Clooney, Lorraine A. Draper, Colin Hill, Ken Nally, Fergus Shanahan, Stefan Andersson-Engels, Silvia Melgar
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTConflicting evidence exists on the association between consumption of non-steroidal anti-inflammatory drugs (NSAIDs) and symptomatic worsening of inflammatory bowel disease (IBD). We hypothesized that the heterogeneous prevalence of pathobion
Externí odkaz:
https://doaj.org/article/2d0d405171d54900a09f61fb483c042d
Autor:
Conor Feehily, Ian J. O’Neill, Calum J. Walsh, Rebecca L. Moore, Sarah Louise Killeen, Aisling A. Geraghty, Elaine M. Lawton, David Byrne, Rocio Sanchez-Gallardo, Sai Ravi Chandra Nori, Ida Busch Nielsen, Esther Wortmann, Elizabeth Matthews, Roisin O’Flaherty, Pauline M. Rudd, David Groeger, Fergus Shanahan, Radka Saldova, Fionnuala M. McAuliffe, Douwe Van Sinderen, Paul D. Cotter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract A significant proportion of the infant gut microbiome is considered to be acquired from the mother during and after birth. Thus begins a lifelong and dynamic relationship with microbes that has an enduring impact on host health. Based on a c
Externí odkaz:
https://doaj.org/article/26650c16de684337b8c9307fea1f8d0c
Autor:
Peter Cronin, Siobhan McCarthy, Cian Hurley, Tarini Shankar Ghosh, Jakki C. Cooney, Ann-Marie Tobin, Michelle Murphy, Eibhlís M. O’Connor, Fergus Shanahan, Paul W. O’Toole
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionThe chronic inflammatory skin disease Hidradenitis suppurativa (HS) is strongly associated with Crohn’s Disease (CD). HS and CD share clinical similarities and similar inflammatory pathways are upregulated in both conditions. Increased
Externí odkaz:
https://doaj.org/article/f6100021721f40fab2505dee5913ea94
Autor:
Stephen R. Stockdale, Andrey N. Shkoporov, Ekaterina V. Khokhlova, Karen M. Daly, Siobhan A. McDonnell, Orla O’ Regan, James A. Nolan, Thomas D. S. Sutton, Adam G. Clooney, Feargal J. Ryan, Donal Sheehan, Aonghus Lavelle, Lorraine A. Draper, Fergus Shanahan, R. Paul Ross, Colin Hill
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
A longitudinal analysis of unamplified fecal virome of healthy controls and IBD patients reveals interpersonal variability is a factor that limits our ability to identify associations between the virome composition and IBD.
Externí odkaz:
https://doaj.org/article/8da71355cc6f4f01bd869790a35b2b7f
Autor:
Jerzy A. Woznicki, Nisha Saini, Peter Flood, Subhasree Rajaram, Ciaran M. Lee, Panagiota Stamou, Agnieszka Skowyra, Milan Bustamante-Garrido, Karine Regazzoni, Nyree Crawford, Simon S. McDade, Daniel B. Longley, Pedro Aza-Blanc, Fergus Shanahan, Syed A. Zulquernain, Jane McCarthy, Silvia Melgar, Bradford L. McRae, Ken Nally
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-15 (2021)
Abstract Rewiring of host cytokine networks is a key feature of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD). Th1-type cytokines—IFN-γ and TNF-α—occupy critical nodes within these networks and both are associated with disrup
Externí odkaz:
https://doaj.org/article/3fd851ad37fa451687518ec09ff3247a
Autor:
Nicole R. Narayan, Thomas Weinmaier, Emilio J. Laserna-Mendieta, Marcus J. Claesson, Fergus Shanahan, Karim Dabbagh, Shoko Iwai, Todd Z. DeSantis
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Shotgun metagenomic sequencing reveals the potential in microbial communities. However, lower-cost 16S ribosomal RNA (rRNA) gene sequencing provides taxonomic, not functional, observations. To remedy this, we previously introduced
Externí odkaz:
https://doaj.org/article/2e6b4f969df745a19bcc593256e0fb44
Autor:
Simone Bihl, Marcus de Goffau, Daniel Podlesny, Nicola Segata, Fergus Shanahan, Jens Walter, W. Florian Fricke
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
There is an ongoing controversy around the existence of a prenatal, fetal microbiome in humans, livestock, and other animals. The ‘in utero microbial colonization’ hypothesis challenges the clinical paradigm of the ‘sterile womb’ but has been
Externí odkaz:
https://doaj.org/article/fadafadc052d4e03b39aaf2a61c825aa
Autor:
Julia Eckenberger, James C. Butler, Charles N. Bernstein, Fergus Shanahan, Marcus J. Claesson
Publikováno v:
Microorganisms, Vol 10, Iss 10, p 1963 (2022)
In view of the increasing evidence that commonly prescribed, non-antibiotic drugs interact with the gut microbiome, we re-examined the microbiota variance in inflammatory bowel disease (IBD) to determine the degree to which medication and supplement
Externí odkaz:
https://doaj.org/article/c25d372f8a2c4f759a059fa1b4bede55
Autor:
Eyal Klang, Uri Kopylov, Brynjulf Mortensen, Anders Damholt, Shelly Soffer, Yiftach Barash, Eli Konen, Ana Grinman, Reuma Margalit Yehuda, Martin Buckley, Fergus Shanahan, Rami Eliakim, Shomron Ben-Horin
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background and Study Aims: Deep learning (DL) for video capsule endoscopy (VCE) is an emerging research field. It has shown high accuracy for the detection of Crohn's disease (CD) ulcers. Non-steroidal anti-inflammatory drugs (NSAIDS) are commonly us
Externí odkaz:
https://doaj.org/article/d7ab1502af6d4e7793f9a02800a7392f