Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Fergus, Hamilton"'
Autor:
Sabrina E. Wang, Vivian Viallon, Matthew Lee, Niki Dimou, Fergus Hamilton, Carine Biessy, Tracy O'Mara, Maria Kyrgiou, Emma J. Crosbie, Therese Truong, Gianluca Severi, Rudolf Kaaks, Renée Turzanski Fortner, Matthias B. Schulze, Benedetta Bendinelli, Sieri Sabina, Rosario Tumino, Carlotta Sacerdote, Salvatore Panico, Marta Crous-Bou, Maria-Jose Sánchez, Amaia Aizpurua, Daniel Rodriguez Palacios, Marcela Guevara, Ruth C. Travis, Konstantinos K. Tsilidis, Alicia Heath, James Yarmolinsky, Sabina Rinaldi, Marc J. Gunter, Laure Dossus
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105341- (2024)
Summary: Background: Inflammation and immune dysregulation are hypothesized contributors to endometrial carcinogenesis; however, the precise underlying mechanisms remain unclear. Methods: We measured pre-diagnostically 152 plasma protein biomarkers i
Externí odkaz:
https://doaj.org/article/141e8b2518434ea088f93b8aa644b8af
Autor:
Victoria Hamilton, Sadiyah Sheikh, Alicja Szczepanska, Nick Maskell, Fergus Hamilton, Jonathan P. Reid, Bryan R. Bzdek, James R. D. Murray
Publikováno v:
Bone & Joint Research, Vol 12, Iss 10, Pp 636-643 (2023)
Aims: Orthopaedic surgery uses many varied instruments with high-speed, high-impact, thermal energy and sometimes heavy instruments, all of which potentially result in aerosolization of contaminated blood, tissue, and bone, raising concerns for clini
Externí odkaz:
https://doaj.org/article/29f11511e96740369ea205aae822a03e
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-4 (2023)
Abstract In this commentary, we discuss a recent article in Trials that raised concerns about the number of poorly performed randomised trials in the medical literature and discuss the trials literature more widely. Although we all aim for higher met
Externí odkaz:
https://doaj.org/article/4114b3e335044f34b6ebb6738fd4a354
Autor:
Rory Taylor, Chengyuan Zhang, Deslit George, Sarah Kotecha, Mariam Abdelghaffar, Thorsten Forster, Patricia Dos Santos Rodrigues, Alexander C. Reisinger, Daniel White, Fergus Hamilton, W. John Watkins, David M. Griffith, Peter Ghazal
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104981- (2024)
Summary: Background: Mechanistic studies have established a biological role of sterol metabolism in infection and immunity with clinical data linking deranged cholesterol metabolism during sepsis with poorer outcomes. In this systematic review we ass
Externí odkaz:
https://doaj.org/article/c4ca1ee0b24e424d8cba2b2e11ad2989
Autor:
Fergus Hamilton, Ruth E Mitchell, Andrei Constantinescu, David Hughes, Aubrey Cunnington, Peter Ghazal, Nicholas J. Timpson
Publikováno v:
International Journal of Infectious Diseases, Vol 129, Iss , Pp 251-259 (2023)
Objectives: Severe malaria remains a deadly disease for many young children in low- and middle-income countries. Levels of interleukin (IL)-6 have been shown to identify cases of severe malaria and associate with severity, but it is unknown if this a
Externí odkaz:
https://doaj.org/article/47fdac61a56042b782fee2679b26b6cd
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/820cd3f8f76743a7bb6b7ddf69cf620a
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Iron deficiency is associated with a substantial burden of morbidity. However, supplementation of iron has been linked to increased rates of serious infection in randomised trials of children in sub-Saharan Africa. Randomised trials in other
Externí odkaz:
https://doaj.org/article/fb4bccd8ff134e8aa66500cce794d02c
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-9 (2022)
Abstract Background Inducible expression of heme oxygenase-1 (encoded by the gene HMOX1) may determine protection from heme released during malaria infections. A variable length, short tandem GT(n) repeat (STR) in HMOX1 that may influence gene expres
Externí odkaz:
https://doaj.org/article/28a15e8699944bce87982a38a63192e5
Autor:
Marianna Santopaolo, Michaela Gregorova, Fergus Hamilton, David Arnold, Anna Long, Aurora Lacey, Elizabeth Oliver, Alice Halliday, Holly Baum, Kristy Hamilton, Rachel Milligan, Olivia Pearce, Lea Knezevic, Begonia Morales Aza, Alice Milne, Emily Milodowski, Eben Jones, Rajeka Lazarus, Anu Goenka, Adam Finn, Nicholas Maskell, Andrew D Davidson, Kathleen Gillespie, Linda Wooldridge, Laura Rivino
Publikováno v:
eLife, Vol 12 (2023)
Coronavirus disease-19 (COVID-19) causes immune perturbations which may persist long term, and patients frequently report ongoing symptoms for months after recovery. We assessed immune activation at 3–12 months post hospital admission in 187 sample
Externí odkaz:
https://doaj.org/article/ac5579a825a64cf5b124986504c91cb6
Autor:
Alice Halliday, Anna E. Long, Holly E. Baum, Amy C. Thomas, Kathryn L. Shelley, Elizabeth Oliver, Kapil Gupta, Ore Francis, Maia Kavanagh Williamson, Natalie Di Bartolo, Matthew J. Randell, Yassin Ben-Khoud, Ilana Kelland, Georgina Mortimer, Olivia Ball, Charlie Plumptre, Kyla Chandler, Ulrike Obst, Massimiliano Secchi, Lorenzo Piemonti, Vito Lampasona, Joyce Smith, Michaela Gregorova, Lea Knezevic, Jane Metz, Rachael Barr, Begonia Morales-Aza, Jennifer Oliver, Lucy Collingwood, Benjamin Hitchings, Susan Ring, Linda Wooldridge, Laura Rivino, Nicholas Timpson, Jorgen McKernon, Peter Muir, Fergus Hamilton, David Arnold, Derek N. Woolfson, Anu Goenka, Andrew D. Davidson, Ashley M. Toye, Imre Berger, Mick Bailey, Kathleen M. Gillespie, Alistair J. K. Williams, Adam Finn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Low-volume antibody assays can be used to track SARS-CoV-2 infection rates in settings where active testing for virus is limited and remote sampling is optimal. We developed 12 ELISAs detecting total or antibody isotypes to SARS-CoV-2 nucleocapsid, s
Externí odkaz:
https://doaj.org/article/305a69f5b981428bab7c739f99a8b141