Deficiency in PHD2-mediated hydroxylation of HIF2α underlies Pacak-Zhuang syndrome.

Autor: Ferens FG; Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.; Department of Biochemistry, Faculty of Medicine, University of Toronto, 661 University Avenue, Toronto, ON, M5G 1M1, Canada., Taber CC; Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Stuart S; Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.; Department of Biochemistry, Faculty of Medicine, University of Toronto, 661 University Avenue, Toronto, ON, M5G 1M1, Canada., Hubert M; Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Tarade D; Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Lee JE; Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada., Ohh M; Department of Laboratory Medicine & Pathobiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada. michael.ohh@utoronto.ca.; Department of Biochemistry, Faculty of Medicine, University of Toronto, 661 University Avenue, Toronto, ON, M5G 1M1, Canada. michael.ohh@utoronto.ca.

Publikováno v: Communications biology [Commun Biol] 2024 Feb 28; Vol. 7 (1), pp. 240. Date of Electronic Publication: 2024 Feb 28.

A C-Terminally Truncated Variant of Neurospora crassa VDAC Assembles Into a Partially Functional Form in the Mitochondrial Outer Membrane and Forms Multimers in vitro .

Autor: Ferens FG; Department of Microbiology, University of Manitoba, Winnipeg, MB, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Summers WAT; Department of Microbiology, University of Manitoba, Winnipeg, MB, Canada., Bharaj A; Department of Microbiology, University of Manitoba, Winnipeg, MB, Canada., Stetefeld J; Department of Chemistry, University of Manitoba, Winnipeg, MB, Canada., Court DA; Department of Microbiology, University of Manitoba, Winnipeg, MB, Canada.

Publikováno v: Frontiers in physiology [Front Physiol] 2021 Sep 17; Vol. 12, pp. 739001. Date of Electronic Publication: 2021 Sep 17 (Print Publication: 2021).

A Cholesterol Analog Induces an Oligomeric Reorganization of VDAC.

Autor: Ferens FG; Departments of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada; Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada., Patel TR; Alberta RNA Research and Training Institute, Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, Canada; Li Ka Shing Institute of Virology and Discovery Lab, University of Alberta, Edmonton, Alberta, Canada; Department of Microbiology, Immunology & Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Oriss G; Departments of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada., Court DA; Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada., Stetefeld J; Departments of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada; Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: jorg.stetefeld@umanitoba.ca.

Publikováno v: Biophysical journal [Biophys J] 2019 Mar 05; Vol. 116 (5), pp. 847-859. Date of Electronic Publication: 2019 Feb 01.

A deletion variant partially complements a porin-less strain of Neurospora crassa.

Autor: Ferens FG; a Department of Microbiology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Spicer V; b Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Krokhin OV; c Department of Internal Medicine & Manitoba Centre for Proteomics and Systems Biology, University of Manitoba, Winnipeg, MB R3E 3P4, Canada., Motnenko A; a Department of Microbiology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Summers WA; a Department of Microbiology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Court DA; a Department of Microbiology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.

Publikováno v: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2017 Apr; Vol. 95 (2), pp. 318-327. Date of Electronic Publication: 2016 Nov 02.

Glucose deprivation impairs hypoxia-inducible factor-1α synthesis.

Autor: Hubert, Mia, Stuart, Sarah, Ohh, Michael

Publikováno v: Discover Oncology; 10/28/2024, Vol. 15 Issue 1, p1-14, 14p